(11 nodes) Mixed, incl. Polycystin domain, and NFACT, RNA-binding domain network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	pkd1	Polycystic kidney disease 1a. (4592 aa)
	ppm1k	Protein phosphatase, Mg2+/Mn2+ dependent, 1K. (383 aa)
	pkd2	Polycystic kidney disease 2. (893 aa)
	LOC103477109	Polycystic kidney disease 2-like 1. (756 aa)
	pkhd1l1	Si:ch211-244a23.1. (2524 aa)
	ENSPREP00000022073	Uncharacterized protein. (213 aa)
	pkd1l1	Uncharacterized protein. (2056 aa)
	LOC103460357	Uncharacterized protein. (1583 aa)
	ccdc25	Coiled-coil domain containing 25. (209 aa)
	ENSPREP00000034211	C-type lectin domain-containing protein. (163 aa)
	ENSPREP00000034215	Uncharacterized protein. (147 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000022073	pkd1	ENSPREP00000022073	ENSPREP00000000547	Uncharacterized protein.	Polycystic kidney disease 1a.	0.428
ENSPREP00000034211	ENSPREP00000034215	ENSPREP00000034211	ENSPREP00000034215	C-type lectin domain-containing protein.	Uncharacterized protein.	0.906
ENSPREP00000034211	LOC103460357	ENSPREP00000034211	ENSPREP00000023960	C-type lectin domain-containing protein.	Uncharacterized protein.	0.923
ENSPREP00000034215	ENSPREP00000034211	ENSPREP00000034215	ENSPREP00000034211	Uncharacterized protein.	C-type lectin domain-containing protein.	0.906
LOC103460357	ENSPREP00000034211	ENSPREP00000023960	ENSPREP00000034211	Uncharacterized protein.	C-type lectin domain-containing protein.	0.923
LOC103460357	LOC103477109	ENSPREP00000023960	ENSPREP00000003780	Uncharacterized protein.	Polycystic kidney disease 2-like 1.	0.754
LOC103460357	pkd1	ENSPREP00000023960	ENSPREP00000000547	Uncharacterized protein.	Polycystic kidney disease 1a.	0.401
LOC103460357	pkd2	ENSPREP00000023960	ENSPREP00000002383	Uncharacterized protein.	Polycystic kidney disease 2.	0.754
LOC103477109	LOC103460357	ENSPREP00000003780	ENSPREP00000023960	Polycystic kidney disease 2-like 1.	Uncharacterized protein.	0.754
LOC103477109	pkd1	ENSPREP00000003780	ENSPREP00000000547	Polycystic kidney disease 2-like 1.	Polycystic kidney disease 1a.	0.930
LOC103477109	ppm1k	ENSPREP00000003780	ENSPREP00000002227	Polycystic kidney disease 2-like 1.	Protein phosphatase, Mg2+/Mn2+ dependent, 1K.	0.550
pkd1	ENSPREP00000022073	ENSPREP00000000547	ENSPREP00000022073	Polycystic kidney disease 1a.	Uncharacterized protein.	0.428
pkd1	LOC103460357	ENSPREP00000000547	ENSPREP00000023960	Polycystic kidney disease 1a.	Uncharacterized protein.	0.401
pkd1	LOC103477109	ENSPREP00000000547	ENSPREP00000003780	Polycystic kidney disease 1a.	Polycystic kidney disease 2-like 1.	0.930
pkd1	pkd2	ENSPREP00000000547	ENSPREP00000002383	Polycystic kidney disease 1a.	Polycystic kidney disease 2.	0.931
pkd1	pkhd1l1	ENSPREP00000000547	ENSPREP00000021125	Polycystic kidney disease 1a.	Si:ch211-244a23.1.	0.542
pkd2	LOC103460357	ENSPREP00000002383	ENSPREP00000023960	Polycystic kidney disease 2.	Uncharacterized protein.	0.754
pkd2	pkd1	ENSPREP00000002383	ENSPREP00000000547	Polycystic kidney disease 2.	Polycystic kidney disease 1a.	0.931
pkhd1l1	pkd1	ENSPREP00000021125	ENSPREP00000000547	Si:ch211-244a23.1.	Polycystic kidney disease 1a.	0.542
ppm1k	LOC103477109	ENSPREP00000002227	ENSPREP00000003780	Protein phosphatase, Mg2+/Mn2+ dependent, 1K.	Polycystic kidney disease 2-like 1.	0.550