(11 nodes) Flotillin, and Caveola assembly network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Cav1	Uncharacterized protein. (84 aa)
	cav2	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (177 aa)
	LOC103482185	Caveolae associated protein 1b. (397 aa)
	flot2	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (434 aa)
	LOC103472976	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (350 aa)
	cav3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (163 aa)
	LOC103465217	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (159 aa)
	LOC103469402	Caveolae associated protein 1a. (393 aa)
	flot1	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (427 aa)
	LOC103465345	Low density lipoprotein receptor-related protein 1Aa. (4383 aa)
	LOC103475233	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (428 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cav1	LOC103469402	ENSPREP00000003891	ENSPREP00000014515	Uncharacterized protein.	Caveolae associated protein 1a.	0.697
Cav1	LOC103472976	ENSPREP00000003891	ENSPREP00000011522	Uncharacterized protein.	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.	0.466
Cav1	LOC103475233	ENSPREP00000003891	ENSPREP00000030737	Uncharacterized protein.	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.	0.466
Cav1	LOC103482185	ENSPREP00000003891	ENSPREP00000005200	Uncharacterized protein.	Caveolae associated protein 1b.	0.697
Cav1	cav2	ENSPREP00000003891	ENSPREP00000003908	Uncharacterized protein.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.974
Cav1	cav3	ENSPREP00000003891	ENSPREP00000013872	Uncharacterized protein.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.544
Cav1	flot1	ENSPREP00000003891	ENSPREP00000019284	Uncharacterized protein.	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.	0.466
Cav1	flot2	ENSPREP00000003891	ENSPREP00000010234	Uncharacterized protein.	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.	0.466
LOC103465217	LOC103469402	ENSPREP00000013910	ENSPREP00000014515	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolae associated protein 1a.	0.645
LOC103465217	LOC103472976	ENSPREP00000013910	ENSPREP00000011522	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.	0.624
LOC103465217	LOC103475233	ENSPREP00000013910	ENSPREP00000030737	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.	0.466
LOC103465217	LOC103482185	ENSPREP00000013910	ENSPREP00000005200	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolae associated protein 1b.	0.645
LOC103465217	cav2	ENSPREP00000013910	ENSPREP00000003908	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.925
LOC103465217	cav3	ENSPREP00000013910	ENSPREP00000013872	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.955
LOC103465217	flot1	ENSPREP00000013910	ENSPREP00000019284	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.	0.619
LOC103465217	flot2	ENSPREP00000013910	ENSPREP00000010234	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.	0.466
LOC103465345	cav2	ENSPREP00000022504	ENSPREP00000003908	Low density lipoprotein receptor-related protein 1Aa.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.531
LOC103465345	cav3	ENSPREP00000022504	ENSPREP00000013872	Low density lipoprotein receptor-related protein 1Aa.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.578
LOC103465345	flot1	ENSPREP00000022504	ENSPREP00000019284	Low density lipoprotein receptor-related protein 1Aa.	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.	0.457
LOC103465345	flot2	ENSPREP00000022504	ENSPREP00000010234	Low density lipoprotein receptor-related protein 1Aa.	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.	0.457