(36 nodes) Mixed, incl. Homeobox protein SIX1, N-terminal SD domain, and Eyes absent family network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103465135	Solute carrier family 2 member 15b; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (513 aa)
	LOC103474648	SIX homeobox 5. (902 aa)
	LOC103474650	SIX homeobox 9. (227 aa)
	foxe1	Forkhead box E1. (369 aa)
	six2	SIX homeobox 2a. (290 aa)
	Six3	SIX homeobox 3a. (341 aa)
	rp9	RP9 pre-mRNA splicing factor. (223 aa)
	dlx3	Distal-less homeobox 3b. (281 aa)
	LOC103482157	Distal-less homeobox 4b. (259 aa)
	LOC103481539	SIX homeobox 3b. (277 aa)
	ENSPREP00000008912	Dachshund d. (187 aa)
	ENSPREP00000011029	Uncharacterized protein. (146 aa)
	LOC103469371	Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. (257 aa)
	ENSPREP00000014560	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (483 aa)
	eya4	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (613 aa)
	LOC103463564	Forkhead box E3. (418 aa)
	tgfbi	Transforming growth factor, beta-induced. (628 aa)
	ENSPREP00000018414	Ski_Sno domain-containing protein. (274 aa)
	ENSPREP00000018546	Homeobox domain-containing protein. (298 aa)
	LOC103479785	Retinal homeobox gene 2. (325 aa)
	gbx2	Gastrulation brain homeobox 2. (339 aa)
	pax6	Paired box 6b. (431 aa)
	ENSPREP00000020629	COesterase domain-containing protein. (457 aa)
	pax8	Paired box 8. (495 aa)
	six6	SIX homeobox 6a. (245 aa)
	six1	SIX homeobox 1a. (284 aa)
	six4	SIX homeobox 4a. (587 aa)
	LOC103464861	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (493 aa)
	LOC103476847	Paired box 2a. (322 aa)
	LOC103468456	TEF transcription factor, PAR bZIP family member b. (375 aa)
	shroom2	Uncharacterized protein. (1621 aa)
	eya1	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (621 aa)
	vax1	Ventral anterior homeobox 1. (285 aa)
	LOC103481982	Membrane protein, palmitoylated 2b (MAGUK p55 subfamily member 2); Belongs to the MAGUK family. (429 aa)
	LOC103476496	Orthodenticle homeobox 1. (331 aa)
	galns	Galactosamine (N-acetyl)-6-sulfatase. (497 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000008912	ENSPREP00000014560	ENSPREP00000008912	ENSPREP00000014560	Dachshund d.	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.473
ENSPREP00000008912	LOC103464861	ENSPREP00000008912	ENSPREP00000023889	Dachshund d.	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.473
ENSPREP00000008912	LOC103474648	ENSPREP00000008912	ENSPREP00000000857	Dachshund d.	SIX homeobox 5.	0.481
ENSPREP00000008912	LOC103476496	ENSPREP00000008912	ENSPREP00000031507	Dachshund d.	Orthodenticle homeobox 1.	0.475
ENSPREP00000008912	eya1	ENSPREP00000008912	ENSPREP00000026719	Dachshund d.	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.473
ENSPREP00000008912	eya4	ENSPREP00000008912	ENSPREP00000016347	Dachshund d.	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.473
ENSPREP00000008912	six6	ENSPREP00000008912	ENSPREP00000022893	Dachshund d.	SIX homeobox 6a.	0.488
ENSPREP00000011029	LOC103482157	ENSPREP00000011029	ENSPREP00000006782	Uncharacterized protein.	Distal-less homeobox 4b.	0.556
ENSPREP00000011029	dlx3	ENSPREP00000011029	ENSPREP00000006756	Uncharacterized protein.	Distal-less homeobox 3b.	0.632
ENSPREP00000011029	gbx2	ENSPREP00000011029	ENSPREP00000019725	Uncharacterized protein.	Gastrulation brain homeobox 2.	0.517
ENSPREP00000011029	pax8	ENSPREP00000011029	ENSPREP00000021891	Uncharacterized protein.	Paired box 8.	0.645
ENSPREP00000014560	ENSPREP00000008912	ENSPREP00000014560	ENSPREP00000008912	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Dachshund d.	0.473
ENSPREP00000014560	ENSPREP00000018414	ENSPREP00000014560	ENSPREP00000018414	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Ski_Sno domain-containing protein.	0.473
ENSPREP00000014560	LOC103464861	ENSPREP00000014560	ENSPREP00000023889	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.499
ENSPREP00000014560	LOC103468456	ENSPREP00000014560	ENSPREP00000026119	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	TEF transcription factor, PAR bZIP family member b.	0.652
ENSPREP00000014560	LOC103474648	ENSPREP00000014560	ENSPREP00000000857	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	SIX homeobox 5.	0.553
ENSPREP00000014560	LOC103474650	ENSPREP00000014560	ENSPREP00000000883	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	SIX homeobox 9.	0.553
ENSPREP00000014560	LOC103481539	ENSPREP00000014560	ENSPREP00000007219	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	SIX homeobox 3b.	0.489
ENSPREP00000014560	Six3	ENSPREP00000014560	ENSPREP00000004886	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	SIX homeobox 3a.	0.489
ENSPREP00000014560	eya1	ENSPREP00000014560	ENSPREP00000026719	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.492