(57 nodes) Pentose phosphate pathway, and Glycolysis network (Poecilia reticulata)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	mycbpap	Mycbp associated protein. (773 aa)
	LOC103465753	Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (254 aa)
	TKT	Transketolase. (629 aa)
	LOC103472843	Glyceraldehyde-3-phosphate dehydrogenase. (334 aa)
	rpe	Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (252 aa)
	LOC103472836	Enolase 2. (465 aa)
	LOC103472835	Triosephosphate isomerase. (248 aa)
	aldob	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
	h6pd	Hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase). (791 aa)
	LOC103461260	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (363 aa)
	rbm45	RNA binding motif protein 45. (461 aa)
	taldo1	Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (339 aa)
	rbks	Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (312 aa)
	pgls	6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (257 aa)
	LOC103462680	Pyruvate kinase; Belongs to the pyruvate kinase family. (607 aa)
	parp6	Poly [ADP-ribose] polymerase. (642 aa)
	pgk1	Phosphoglycerate kinase. (417 aa)
	LOC103482255	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (820 aa)
	LOC103467627	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (552 aa)
	LOC103473575	Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (239 aa)
	rpia	Ribose 5-phosphate isomerase A (ribose 5-phosphate epimerase). (284 aa)
	pgm2	Phosphoglucomutase 2. (611 aa)
	LOC103478109	Pyruvate kinase; Belongs to the pyruvate kinase family. (526 aa)
	LOC103465119	Transketolase a. (652 aa)
	bpgm	Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (258 aa)
	pfkl	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (780 aa)
	gck	Phosphotransferase. (433 aa)
	pck1	Phosphoenolpyruvate carboxykinase 1 (soluble). (624 aa)
	LOC103462836	ADP-dependent glucokinase 2. (489 aa)
	gapdh	Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
	eno2	Uncharacterized protein. (434 aa)
	Tpi1	Triosephosphate isomerase. (312 aa)
	gapdhs	Glyceraldehyde-3-phosphate dehydrogenase. (335 aa)
	adpgk	ADP-dependent glucokinase. (510 aa)
	eno1	Enolase 1a, (alpha). (432 aa)
	LOC103466422	Pyruvate kinase; Belongs to the pyruvate kinase family. (530 aa)
	LOC103466421	Poly (ADP-ribose) polymerase family, member 6b. (492 aa)
	pgd	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (483 aa)
	LOC103470739	Fructose-1,6-bisphosphatase 1a; Belongs to the FBPase class 1 family. (338 aa)
	LOC103470743	Fructose-1,6-bisphosphatase 2; Belongs to the FBPase class 1 family. (333 aa)
	LOC103465370	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (761 aa)
	aldoc	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (363 aa)
	LOC103466381	Glucose-6-phosphate isomerase; Belongs to the GPI family. (547 aa)
	dera	Deoxyribose-phosphate aldolase (putative). (397 aa)
	ENSPREP00000027592	Enolase 4. (546 aa)
	pfkp	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (789 aa)
	pgam1	Uncharacterized protein. (178 aa)
	ENSPREP00000028385	Uncharacterized protein. (62 aa)
	LOC103467440	Transketolase b. (626 aa)
	LOC103478624	Si:dkey-12j5.1. (361 aa)
	LOC103473350	Fructose-bisphosphatase 1; Belongs to the FBPase class 1 family. (337 aa)
	pgm1	Phosphoglucomutase 1; Belongs to the phosphohexose mutase family. (561 aa)
	LOC103467320	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (501 aa)
	LOC103465589	Enolase 1b, (alpha). (434 aa)
	LOC103467300	6-phosphofructokinase; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily. (754 aa)
	LOC103459301	TP53 induced glycolysis regulatory phosphatase b. (247 aa)
	LOC103481404	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (363 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000027592	ENSPREP00000028385	ENSPREP00000027592	ENSPREP00000028385	Enolase 4.	Uncharacterized protein.	0.646
ENSPREP00000027592	LOC103459301	ENSPREP00000027592	ENSPREP00000033754	Enolase 4.	TP53 induced glycolysis regulatory phosphatase b.	0.646
ENSPREP00000027592	LOC103461260	ENSPREP00000027592	ENSPREP00000006384	Enolase 4.	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	0.509
ENSPREP00000027592	LOC103462680	ENSPREP00000027592	ENSPREP00000008398	Enolase 4.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.692
ENSPREP00000027592	LOC103465119	ENSPREP00000027592	ENSPREP00000011752	Enolase 4.	Transketolase a.	0.517
ENSPREP00000027592	LOC103465370	ENSPREP00000027592	ENSPREP00000024264	Enolase 4.	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.	0.631
ENSPREP00000027592	LOC103465589	ENSPREP00000027592	ENSPREP00000033177	Enolase 4.	Enolase 1b, (alpha).	0.535
ENSPREP00000027592	LOC103465753	ENSPREP00000027592	ENSPREP00000000536	Enolase 4.	Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.	0.646
ENSPREP00000027592	LOC103466381	ENSPREP00000027592	ENSPREP00000024990	Enolase 4.	Glucose-6-phosphate isomerase; Belongs to the GPI family.	0.727
ENSPREP00000027592	LOC103466421	ENSPREP00000027592	ENSPREP00000023597	Enolase 4.	Poly (ADP-ribose) polymerase family, member 6b.	0.692
ENSPREP00000027592	LOC103466422	ENSPREP00000027592	ENSPREP00000023533	Enolase 4.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.692
ENSPREP00000027592	LOC103467300	ENSPREP00000027592	ENSPREP00000033359	Enolase 4.	6-phosphofructokinase; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.	0.631
ENSPREP00000027592	LOC103467440	ENSPREP00000027592	ENSPREP00000028494	Enolase 4.	Transketolase b.	0.517
ENSPREP00000027592	LOC103470739	ENSPREP00000027592	ENSPREP00000023806	Enolase 4.	Fructose-1,6-bisphosphatase 1a; Belongs to the FBPase class 1 family.	0.413
ENSPREP00000027592	LOC103470743	ENSPREP00000027592	ENSPREP00000023859	Enolase 4.	Fructose-1,6-bisphosphatase 2; Belongs to the FBPase class 1 family.	0.413
ENSPREP00000027592	LOC103472835	ENSPREP00000027592	ENSPREP00000001953	Enolase 4.	Triosephosphate isomerase.	0.835
ENSPREP00000027592	LOC103472836	ENSPREP00000027592	ENSPREP00000001896	Enolase 4.	Enolase 2.	0.536
ENSPREP00000027592	LOC103472843	ENSPREP00000027592	ENSPREP00000001538	Enolase 4.	Glyceraldehyde-3-phosphate dehydrogenase.	0.733
ENSPREP00000027592	LOC103473350	ENSPREP00000027592	ENSPREP00000030296	Enolase 4.	Fructose-bisphosphatase 1; Belongs to the FBPase class 1 family.	0.413
ENSPREP00000027592	LOC103473575	ENSPREP00000027592	ENSPREP00000009569	Enolase 4.	Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.	0.646