STRINGSTRING
tat tat LOC103481426 LOC103481426 acy1 acy1 ENSPREP00000001718 ENSPREP00000001718 SHMT2 SHMT2 hacl1 hacl1 grhpr grhpr LOC103460525 LOC103460525 LOC103458637 LOC103458637 mtr mtr ENSPREP00000004578 ENSPREP00000004578 LOC103472253 LOC103472253 LOC103479587 LOC103479587 LOC103461226 LOC103461226 phgdh phgdh amt amt mthfd1l mthfd1l phykpl phykpl mat2b mat2b AHCYL1 AHCYL1 pdpr pdpr ENSPREP00000006862 ENSPREP00000006862 LOC103481537 LOC103481537 glyctk glyctk ilvbl ilvbl dglucy dglucy LOC103460681 LOC103460681 cth cth LOC103461416 LOC103461416 LOC103466594 LOC103466594 gls2 gls2 gart gart oat oat hykk hykk thnsl2 thnsl2 alas1 alas1 aass aass fpgs fpgs iba57 iba57 tyms tyms fdx1 fdx1 LOC103459528 LOC103459528 SDS SDS gldc gldc FADS6 FADS6 ENSPREP00000012474 ENSPREP00000012474 sardh sardh shmt2 shmt2 LOC103472444 LOC103472444 isoc2 isoc2 psat1 psat1 ALDH18A1 ALDH18A1 mthfr mthfr arg2 arg2 LOC103469985 LOC103469985 carnmt1 carnmt1 otc otc LOC103481118 LOC103481118 LOC103473691 LOC103473691 LOC103477344 LOC103477344 LOC103465877 LOC103465877 hao1 hao1 LOC103468992 LOC103468992 nags nags ENSPREP00000017739 ENSPREP00000017739 mthfs mthfs dhfr dhfr cndp2 cndp2 LOC103472482 LOC103472482 cps1 cps1 LOC103465980 LOC103465980 glud1 glud1 LOC103470081 LOC103470081 LOC103470080 LOC103470080 LOC103474492 LOC103474492 LOC103459585 LOC103459585 LOC103463995 LOC103463995 ahcyl1 ahcyl1 LOC103463960 LOC103463960 pipox pipox aldh7a1 aldh7a1 ENSPREP00000022276 ENSPREP00000022276 ASS1 ASS1 pgp pgp LOC103464825 LOC103464825 ENSPREP00000023632 ENSPREP00000023632 LOC103481893 LOC103481893 HLCS HLCS LOC103459710 LOC103459710 LOC103463929 LOC103463929 iah1 iah1 LOC103466078 LOC103466078 l2hgdh l2hgdh hddc3 hddc3 LOC103473263 LOC103473263 shmt1 shmt1 LOC103457821 LOC103457821 LOC103476873 LOC103476873 Cad Cad hdc hdc LOC103457629 LOC103457629 dmgdh dmgdh LOC103473309 LOC103473309 fdxr fdxr hao2 hao2 ppat ppat LOC103463823 LOC103463823 impact impact LOC103465496 LOC103465496 RIDA RIDA LOC103466197 LOC103466197 hoga1 hoga1 ENSPREP00000031431 ENSPREP00000031431 mthfd2 mthfd2 LOC103457187 LOC103457187 LOC103470277 LOC103470277 lgsn lgsn mthfd1 mthfd1 psph psph mtfmt mtfmt LOC103459803 LOC103459803 LOC103468004 LOC103468004 THNSL1 THNSL1 gcsh gcsh
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
tatTyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. (449 aa)
LOC103481426Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. (770 aa)
acy1Aminoacylase 1. (419 aa)
ENSPREP00000001718Uncharacterized protein. (156 aa)
SHMT2Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (530 aa)
hacl12-hydroxyacyl-CoA lyase 1; Belongs to the TPP enzyme family. (568 aa)
grhprGlyoxylate reductase/hydroxypyruvate reductase a; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (329 aa)
LOC103460525Serine palmitoyltransferase, long chain base subunit 2a. (565 aa)
LOC103458637L-threonine dehydrogenase 2. (308 aa)
mtrMethionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1275 aa)
ENSPREP00000004578CN hydrolase domain-containing protein. (404 aa)
LOC103472253Biotinidase. (368 aa)
LOC103479587Glutamine synthetase. (406 aa)
LOC103461226Trimethyllysine hydroxylase, epsilon. (407 aa)
phgdhD-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (527 aa)
amtAminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. (415 aa)
mthfd1lMethylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like. (695 aa)
phykpl5-phosphohydroxy-L-lysine phospho-lyase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (437 aa)
mat2bMethionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. (325 aa)
AHCYL1Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. (550 aa)
pdprPyruvate dehydrogenase phosphatase regulatory subunit. (892 aa)
ENSPREP00000006862Uncharacterized protein. (144 aa)
LOC103481537Glutamate dehydrogenase 1b; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (542 aa)
glyctkGlycerate kinase. (524 aa)
ilvblIlvB (bacterial acetolactate synthase)-like; Belongs to the TPP enzyme family. (625 aa)
dglucyD-glutamate cyclase. (627 aa)
LOC103460681Serine dehydratase-like. (313 aa)
cthCystathionase (cystathionine gamma-lyase), like. (441 aa)
LOC103461416Serine--pyruvate aminotransferase. (360 aa)
LOC103466594Glyoxylate reductase/hydroxypyruvate reductase b; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (359 aa)
gls2Glutaminase 2a (liver, mitochondrial). (600 aa)
gartTrifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. (1010 aa)
oatOrnithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (478 aa)
hykkHydroxylysine kinase, tandem duplicate 1. (367 aa)
thnsl2Threonine synthase-like 2. (401 aa)
alas15-aminolevulinate synthase. (623 aa)
aassAminoadipate-semialdehyde synthase. (931 aa)
fpgsFolylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (576 aa)
iba57Iron-sulfur cluster assembly factor IBA57. (366 aa)
tymsThymidylate synthetase. (322 aa)
fdx12Fe-2S ferredoxin-type domain-containing protein. (165 aa)
LOC103459528Si:ch73-263o4.3. (313 aa)
SDSSerine dehydratase. (346 aa)
gldcGlycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (1043 aa)
FADS6Fatty acid desaturase 6. (352 aa)
ENSPREP00000012474Lyase_1 domain-containing protein. (94 aa)
sardhSarcosine dehydrogenase. (916 aa)
shmt2Serine hydroxymethyltransferase 2 (mitochondrial). (515 aa)
LOC103472444Zgc:136493; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (326 aa)
isoc2Isochorismatase domain containing 2. (209 aa)
psat1Phosphoserine aminotransferase. (369 aa)
ALDH18A1Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. (779 aa)
mthfrMethylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (645 aa)
arg2Arginase. (346 aa)
LOC103469985Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like. (398 aa)
carnmt1Carnosine N-methyltransferase 1. (408 aa)
otcOrnithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (319 aa)
LOC103481118Formimidoyltransferase cyclodeaminase. (539 aa)
LOC103473691S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (396 aa)
LOC103477344PALP domain-containing protein. (529 aa)
LOC103465877Zgc:114181. (494 aa)
hao1Hydroxyacid oxidase (glycolate oxidase) 1. (373 aa)
LOC103468992Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (426 aa)
nagsN-acetylglutamate synthase. (568 aa)
ENSPREP00000017739Uncharacterized protein. (65 aa)
mthfs5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (199 aa)
dhfrDihydrofolate reductase. (187 aa)
cndp2M20_dimer domain-containing protein. (529 aa)
LOC103472482Carnosine dipeptidase 2. (505 aa)
cps1Carbamoyl-phosphate synthase 1, mitochondrial. (1505 aa)
LOC103465980Uncharacterized protein. (353 aa)
glud1Glutamate dehydrogenase 1a; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (541 aa)
LOC103470081Hcy-binding domain-containing protein. (435 aa)
LOC103470080Hcy-binding domain-containing protein; Involved in the regulation of homocysteine metabolism. (397 aa)
LOC103474492Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (582 aa)
LOC103459585Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (362 aa)
LOC103463995Glutamine synthetase. (373 aa)
ahcyl1Adenosylhomocysteinase-like 1; Belongs to the adenosylhomocysteinase family. (555 aa)
LOC103463960Serine--pyruvate aminotransferase. (434 aa)
pipoxPipecolic acid oxidase. (388 aa)
aldh7a1Aldehyde dehydrogenase 7 family, member A1; Belongs to the aldehyde dehydrogenase family. (542 aa)
ENSPREP00000022276Uncharacterized protein. (107 aa)
ASS1Argininosuccinate synthase 1. (483 aa)
pgpPhosphoglycolate phosphatase; Belongs to the HAD-like hydrolase superfamily. (312 aa)
LOC103464825Glutaminase 2b (liver, mitochondrial). (514 aa)
ENSPREP000000236322-Hacid_dh_C domain-containing protein. (103 aa)
LOC103481893Arginase. (371 aa)
HLCSHolocarboxylase synthetase. (912 aa)
LOC10345971010-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. (923 aa)
LOC103463929Zgc:172121. (369 aa)
iah1Isoamyl acetate hydrolyzing esterase 1 (putative). (242 aa)
LOC103466078AdoHcyase_NAD domain-containing protein; Belongs to the adenosylhomocysteinase family. (578 aa)
l2hgdhL-2-hydroxyglutarate dehydrogenase. (447 aa)
hddc3HD domain containing 3. (189 aa)
LOC103473263S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (390 aa)
shmt1Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (442 aa)
LOC103457821Serine palmitoyltransferase, long chain base subunit 2b. (564 aa)
LOC103476873S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (395 aa)
CadGlutamine amidotransferase type-1 domain-containing protein. (273 aa)
hdcHistidine decarboxylase. (670 aa)
LOC103457629L-threonine dehydrogenase. (374 aa)
dmgdhDimethylglycine dehydrogenase. (870 aa)
LOC103473309Betaine-homocysteine methyltransferase; Involved in the regulation of homocysteine metabolism. (397 aa)
fdxrNADPH:adrenodoxin oxidoreductase, mitochondrial. (462 aa)
hao2Hydroxyacid oxidase 2 (long chain). (392 aa)
ppatAmidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (502 aa)
LOC103463823AIRC domain-containing protein. (1012 aa)
impactImpact RWD domain protein. (320 aa)
LOC10346549610-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. (902 aa)
RIDAReactive intermediate imine deaminase A homolog. (136 aa)
LOC103466197Zgc:153031. (198 aa)
hoga14-hydroxy-2-oxoglutarate aldolase 1; Belongs to the DapA family. (323 aa)
ENSPREP00000031431Glutamine synthetase. (345 aa)
mthfd2Uncharacterized protein. (338 aa)
LOC103457187Glutaminase a. (617 aa)
LOC103470277S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (362 aa)
lgsnLengsin, lens protein with glutamine synthetase domain; Belongs to the glutamine synthetase family. (682 aa)
mthfd1Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b. (934 aa)
psphPhosphoserine phosphatase. (244 aa)
mtfmtMitochondrial methionyl-tRNA formyltransferase. (374 aa)
LOC103459803Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (587 aa)
LOC1034680045-aminolevulinate synthase. (615 aa)
THNSL1Threonine synthase like 1. (723 aa)
gcshGlycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (174 aa)
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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