STRINGSTRING
SHMT2 SHMT2 amt amt mthfd1l mthfd1l gart gart fpgs fpgs iba57 iba57 tyms tyms gldc gldc shmt2 shmt2 LOC103469985 LOC103469985 LOC103481118 LOC103481118 mthfs mthfs dhfr dhfr LOC103466197 LOC103466197 mthfd2 mthfd2 mthfd1 mthfd1 mtfmt mtfmt gcsh gcsh
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SHMT2Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (530 aa)
amtAminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. (415 aa)
mthfd1lMethylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like. (695 aa)
gartTrifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. (1010 aa)
fpgsFolylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (576 aa)
iba57Iron-sulfur cluster assembly factor IBA57. (366 aa)
tymsThymidylate synthetase. (322 aa)
gldcGlycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (1043 aa)
shmt2Serine hydroxymethyltransferase 2 (mitochondrial). (515 aa)
LOC103469985Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like. (398 aa)
LOC103481118Formimidoyltransferase cyclodeaminase. (539 aa)
mthfs5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (199 aa)
dhfrDihydrofolate reductase. (187 aa)
LOC103466197Zgc:153031. (198 aa)
mthfd2Uncharacterized protein. (338 aa)
mthfd1Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b. (934 aa)
mtfmtMitochondrial methionyl-tRNA formyltransferase. (374 aa)
gcshGlycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (174 aa)
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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