(16 nodes) Mixed, incl. Rho guanine nucleotide exchange factor 10/17, and Ephexin-like network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103461318	Uncharacterized protein. (625 aa)
	LOC103461319	Pleckstrin homology domain-containing family G member 3-like. (625 aa)
	Plekhg1	DH domain-containing protein. (270 aa)
	ENSPREP00000012697	Uncharacterized protein. (532 aa)
	LOC103467571	FYVE, RhoGEF and PH domain containing 3. (621 aa)
	ENSPREP00000014835	SH3 domain-containing protein. (133 aa)
	ENSPREP00000014850	DH domain-containing protein. (196 aa)
	arhgef19	Rho guanine nucleotide exchange factor (GEF) 19. (972 aa)
	LOC103470008	Rho guanine nucleotide exchange factor 28. (1467 aa)
	ENSPREP00000019580	Si:ch73-212j7.3. (455 aa)
	arhgef10l	Rho guanine nucleotide exchange factor (GEF) 10-like a. (997 aa)
	Arhgef28	Phorbol-ester/DAG-type domain-containing protein. (99 aa)
	fgd4	FYVE, RhoGEF and PH domain containing 4. (690 aa)
	ENSPREP00000031204	Uncharacterized protein. (754 aa)
	ENSPREP00000031222	DH domain-containing protein. (231 aa)
	arhgef10	Rho guanine nucleotide exchange factor (GEF) 10. (1441 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000012697	ENSPREP00000031204	ENSPREP00000012697	ENSPREP00000031204	Uncharacterized protein.	Uncharacterized protein.	0.888
ENSPREP00000012697	Plekhg1	ENSPREP00000012697	ENSPREP00000008405	Uncharacterized protein.	DH domain-containing protein.	0.408
ENSPREP00000019580	LOC103461318	ENSPREP00000019580	ENSPREP00000007357	Si:ch73-212j7.3.	Uncharacterized protein.	0.892
ENSPREP00000019580	LOC103461319	ENSPREP00000019580	ENSPREP00000007387	Si:ch73-212j7.3.	Pleckstrin homology domain-containing family G member 3-like.	0.892
ENSPREP00000031204	ENSPREP00000012697	ENSPREP00000031204	ENSPREP00000012697	Uncharacterized protein.	Uncharacterized protein.	0.888
ENSPREP00000031204	ENSPREP00000031222	ENSPREP00000031204	ENSPREP00000031222	Uncharacterized protein.	DH domain-containing protein.	0.879
ENSPREP00000031222	ENSPREP00000031204	ENSPREP00000031222	ENSPREP00000031204	DH domain-containing protein.	Uncharacterized protein.	0.879
LOC103461318	ENSPREP00000019580	ENSPREP00000007357	ENSPREP00000019580	Uncharacterized protein.	Si:ch73-212j7.3.	0.892
LOC103461318	Plekhg1	ENSPREP00000007357	ENSPREP00000008405	Uncharacterized protein.	DH domain-containing protein.	0.766
LOC103461319	ENSPREP00000019580	ENSPREP00000007387	ENSPREP00000019580	Pleckstrin homology domain-containing family G member 3-like.	Si:ch73-212j7.3.	0.892
LOC103461319	Plekhg1	ENSPREP00000007387	ENSPREP00000008405	Pleckstrin homology domain-containing family G member 3-like.	DH domain-containing protein.	0.766
Plekhg1	ENSPREP00000012697	ENSPREP00000008405	ENSPREP00000012697	DH domain-containing protein.	Uncharacterized protein.	0.408
Plekhg1	LOC103461318	ENSPREP00000008405	ENSPREP00000007357	DH domain-containing protein.	Uncharacterized protein.	0.766
Plekhg1	LOC103461319	ENSPREP00000008405	ENSPREP00000007387	DH domain-containing protein.	Pleckstrin homology domain-containing family G member 3-like.	0.766