(11 nodes) D-Glutamine and D-glutamate metabolism, and GPR domain network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103481426	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. (770 aa)
	ENSPREP00000001718	Uncharacterized protein. (156 aa)
	LOC103481537	Glutamate dehydrogenase 1b; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (542 aa)
	dglucy	D-glutamate cyclase. (627 aa)
	gls2	Glutaminase 2a (liver, mitochondrial). (600 aa)
	ALDH18A1	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. (779 aa)
	glud1	Glutamate dehydrogenase 1a; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (541 aa)
	LOC103463995	Glutamine synthetase. (373 aa)
	LOC103464825	Glutaminase 2b (liver, mitochondrial). (514 aa)
	l2hgdh	L-2-hydroxyglutarate dehydrogenase. (447 aa)
	LOC103457187	Glutaminase a. (617 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALDH18A1	ENSPREP00000001718	ENSPREP00000013516	ENSPREP00000001718	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	Uncharacterized protein.	0.971
ALDH18A1	LOC103457187	ENSPREP00000013516	ENSPREP00000031504	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	Glutaminase a.	0.971
ALDH18A1	LOC103463995	ENSPREP00000013516	ENSPREP00000020471	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	Glutamine synthetase.	0.937
ALDH18A1	LOC103464825	ENSPREP00000013516	ENSPREP00000023517	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	Glutaminase 2b (liver, mitochondrial).	0.971
ALDH18A1	LOC103481426	ENSPREP00000013516	ENSPREP00000000843	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	0.999
ALDH18A1	LOC103481537	ENSPREP00000013516	ENSPREP00000007110	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	Glutamate dehydrogenase 1b; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.989
ALDH18A1	gls2	ENSPREP00000013516	ENSPREP00000009351	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	Glutaminase 2a (liver, mitochondrial).	0.971
ALDH18A1	glud1	ENSPREP00000013516	ENSPREP00000018700	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	Glutamate dehydrogenase 1a; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.989
ENSPREP00000001718	ALDH18A1	ENSPREP00000001718	ENSPREP00000013516	Uncharacterized protein.	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	0.971
ENSPREP00000001718	LOC103463995	ENSPREP00000001718	ENSPREP00000020471	Uncharacterized protein.	Glutamine synthetase.	0.945
ENSPREP00000001718	LOC103481426	ENSPREP00000001718	ENSPREP00000000843	Uncharacterized protein.	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	0.971
ENSPREP00000001718	LOC103481537	ENSPREP00000001718	ENSPREP00000007110	Uncharacterized protein.	Glutamate dehydrogenase 1b; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.953
ENSPREP00000001718	dglucy	ENSPREP00000001718	ENSPREP00000008185	Uncharacterized protein.	D-glutamate cyclase.	0.900
ENSPREP00000001718	glud1	ENSPREP00000001718	ENSPREP00000018700	Uncharacterized protein.	Glutamate dehydrogenase 1a; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.953
ENSPREP00000001718	l2hgdh	ENSPREP00000001718	ENSPREP00000026561	Uncharacterized protein.	L-2-hydroxyglutarate dehydrogenase.	0.800
LOC103457187	ALDH18A1	ENSPREP00000031504	ENSPREP00000013516	Glutaminase a.	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	0.971
LOC103457187	LOC103463995	ENSPREP00000031504	ENSPREP00000020471	Glutaminase a.	Glutamine synthetase.	0.945
LOC103457187	LOC103481426	ENSPREP00000031504	ENSPREP00000000843	Glutaminase a.	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	0.971
LOC103457187	LOC103481537	ENSPREP00000031504	ENSPREP00000007110	Glutaminase a.	Glutamate dehydrogenase 1b; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.953
LOC103457187	dglucy	ENSPREP00000031504	ENSPREP00000008185	Glutaminase a.	D-glutamate cyclase.	0.900