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Dctpp1 Dctpp1 LOC103456889 LOC103456889 LOC103465407 LOC103465407 nt5c2 nt5c2 itpa itpa LOC103478583 LOC103478583 cant1 cant1 LOC103466890 LOC103466890 LOC103465759 LOC103465759 LOC103459907 LOC103459907 AMPD2 AMPD2 LOC103479018 LOC103479018 ENSPREP00000007515 ENSPREP00000007515 entpd1 entpd1 entpd4 entpd4 ak2 ak2 LOC103468725 LOC103468725 pde1b pde1b guk1 guk1 aprt aprt LOC103457410 LOC103457410 LOC103476686 LOC103476686 LOC103457375 LOC103457375 tpmt tpmt LOC103473675 LOC103473675 entpd5 entpd5 NT5C3B NT5C3B LOC103457335 LOC103457335 ak6 ak6 ampd1 ampd1 nt5e nt5e LOC103478359 LOC103478359 ak7 ak7 ENSPREP00000017807 ENSPREP00000017807 impdh2 impdh2 entpd6 entpd6 LOC103466012 LOC103466012 LOC103467180 LOC103467180 LOC103457894 LOC103457894 LOC103464121 LOC103464121 LOC103479836 LOC103479836 ak1 ak1 LOC103472033 LOC103472033 gmps gmps pde4d pde4d ak5 ak5 adsl adsl nt5c3a nt5c3a pde7a pde7a atic atic LOC103476524 LOC103476524 ak4 ak4 dck dck pde1a pde1a LOC103458543 LOC103458543 NT5M NT5M LOC103476980 LOC103476980 LOC103458579 LOC103458579 pde3b pde3b ampd3 ampd3 pde10a pde10a
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
Predicted Interactions
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gene co-occurrence
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Dctpp1dCTP pyrophosphatase 1; Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism. (160 aa)
LOC103456889Phosphodiesterase. (874 aa)
LOC103465407Calcium activated nucleotidase 1b. (408 aa)
nt5c25'-nucleotidase, cytosolic IIb. (558 aa)
itpaInosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. (195 aa)
LOC103478583Phosphodiesterase. (849 aa)
cant1Calcium activated nucleotidase 1a. (425 aa)
LOC103466890Zgc:103759. (252 aa)
LOC103465759AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (641 aa)
LOC103459907Zgc:110540. (260 aa)
AMPD2AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (943 aa)
LOC103479018Phosphodiesterase. (758 aa)
ENSPREP00000007515Uncharacterized protein. (63 aa)
entpd1Ectonucleoside triphosphate diphosphohydrolase 1; Belongs to the GDA1/CD39 NTPase family. (498 aa)
entpd4Ectonucleoside triphosphate diphosphohydrolase 4; Belongs to the GDA1/CD39 NTPase family. (618 aa)
ak2Adenylate kinase 2, mitochondrial; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis. (243 aa)
LOC103468725Phosphodiesterase. (746 aa)
pde1bPhosphodiesterase. (519 aa)
guk1Guanylate kinase 1a. (211 aa)
aprtAdenine phosphoribosyltransferase. (180 aa)
LOC103457410Ectonucleotide pyrophosphatase/phosphodiesterase 1. (834 aa)
LOC103476686Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (457 aa)
LOC1034573755'-nucleotidase, cytosolic IB b. (367 aa)
tpmtThiopurine S-methyltransferase, tandem duplicate 1. (234 aa)
LOC1034736755'-nucleotidase, cytosolic II, like 1. (505 aa)
entpd5Ectonucleoside triphosphate diphosphohydrolase 5a; Belongs to the GDA1/CD39 NTPase family. (496 aa)
NT5C3B5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family. (280 aa)
LOC103457335Uncharacterized protein. (715 aa)
ak6Adenylate kinase isoenzyme 6; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation; Belongs to the adenylate kinase family. AK6 subfamily. (173 aa)
ampd1AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (726 aa)
nt5e5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. (647 aa)
LOC103478359Ectonucleoside triphosphate diphosphohydrolase 3; Belongs to the GDA1/CD39 NTPase family. (480 aa)
ak7Adenylate kinase 7b. (699 aa)
ENSPREP00000017807Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (233 aa)
impdh2Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (521 aa)
entpd6Ectonucleoside triphosphate diphosphohydrolase 6; Belongs to the GDA1/CD39 NTPase family. (429 aa)
LOC103466012Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (626 aa)
LOC103467180AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (835 aa)
LOC103457894Ectonucleoside triphosphate diphosphohydrolase 5b; Belongs to the GDA1/CD39 NTPase family. (427 aa)
LOC103464121Guanylate kinase 1b. (233 aa)
LOC103479836Phosphodiesterase. (636 aa)
ak1Adenylate kinase isoenzyme 1; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. (200 aa)
LOC1034720335'-nucleotidase, cytosolic IAa. (387 aa)
gmpsGuanine monophosphate synthase. (690 aa)
pde4dPhosphodiesterase. (787 aa)
ak5Adenylate kinase 5; Belongs to the adenylate kinase family. (562 aa)
adslAdenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (481 aa)
nt5c3a5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family. (331 aa)
pde7aPhosphodiesterase. (506 aa)
atic5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. (591 aa)
LOC1034765245'-nucleotidase, cytosolic IIa. (573 aa)
ak4Adenylate kinase 4; Belongs to the adenylate kinase family. (190 aa)
dckDeoxycytidine kinase. (263 aa)
pde1aPhosphodiesterase. (691 aa)
LOC103458543Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (466 aa)
NT5M5',3'-nucleotidase, mitochondrial. (230 aa)
LOC103476980Adenosine kinase a. (371 aa)
LOC1034585795'-nucleotidase, cytosolic IAb. (366 aa)
pde3bPhosphodiesterase. (1096 aa)
ampd3Adenosine monophosphate deaminase 3a. (617 aa)
pde10aPhosphodiesterase. (807 aa)
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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