(18 nodes) UTP metabolic process, and Ribonucleoside-diphosphate reductase activity network (Poecilia reticulata)

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Your Input:
	RRM1	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (795 aa)
	LOC103482172	Nucleoside diphosphate kinase. (153 aa)
	cmpk1	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (216 aa)
	ak3	GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (223 aa)
	rrm2b	Ribonucleotide reductase M2 b. (354 aa)
	glrx2	Glutaredoxin 2. (169 aa)
	LOC103469013	NDK domain-containing protein; Belongs to the NDK family. (149 aa)
	LOC103469615	Ectonucleoside triphosphate diphosphohydrolase 2a, tandem duplicate 2; Belongs to the GDA1/CD39 NTPase family. (493 aa)
	ctps1	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (588 aa)
	rrm2	Ribonucleotide reductase M2 polypeptide. (386 aa)
	nme3	Nucleoside diphosphate kinase. (180 aa)
	LOC103469155	Nucleoside diphosphate kinase. (236 aa)
	nme7	Nucleoside diphosphate kinase 7; Belongs to the NDK family. (379 aa)
	nme6	Nucleoside diphosphate kinase. (182 aa)
	glrx	Glutaredoxin (thioltransferase). (106 aa)
	nudt2	Nudix (nucleoside diphosphate linked moiety X)-type motif 2. (147 aa)
	cmpk2	Cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial. (417 aa)
	ENSPREP00000032789	RIBORED_LARGE domain-containing protein. (82 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000032789	LOC103469013	ENSPREP00000032789	ENSPREP00000017608	RIBORED_LARGE domain-containing protein.	NDK domain-containing protein; Belongs to the NDK family.	0.945
ENSPREP00000032789	LOC103469155	ENSPREP00000032789	ENSPREP00000024280	RIBORED_LARGE domain-containing protein.	Nucleoside diphosphate kinase.	0.945
ENSPREP00000032789	LOC103469615	ENSPREP00000032789	ENSPREP00000019751	RIBORED_LARGE domain-containing protein.	Ectonucleoside triphosphate diphosphohydrolase 2a, tandem duplicate 2; Belongs to the GDA1/CD39 NTPase family.	0.922
ENSPREP00000032789	LOC103482172	ENSPREP00000032789	ENSPREP00000006159	RIBORED_LARGE domain-containing protein.	Nucleoside diphosphate kinase.	0.945
ENSPREP00000032789	RRM1	ENSPREP00000032789	ENSPREP00000000958	RIBORED_LARGE domain-containing protein.	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	0.907
ENSPREP00000032789	ak3	ENSPREP00000032789	ENSPREP00000011839	RIBORED_LARGE domain-containing protein.	GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.	0.949
ENSPREP00000032789	cmpk1	ENSPREP00000032789	ENSPREP00000010242	RIBORED_LARGE domain-containing protein.	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	0.950
ENSPREP00000032789	cmpk2	ENSPREP00000032789	ENSPREP00000031600	RIBORED_LARGE domain-containing protein.	Cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial.	0.957
ENSPREP00000032789	ctps1	ENSPREP00000032789	ENSPREP00000020542	RIBORED_LARGE domain-containing protein.	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	0.418
ENSPREP00000032789	glrx	ENSPREP00000032789	ENSPREP00000030794	RIBORED_LARGE domain-containing protein.	Glutaredoxin (thioltransferase).	0.905
ENSPREP00000032789	glrx2	ENSPREP00000032789	ENSPREP00000015740	RIBORED_LARGE domain-containing protein.	Glutaredoxin 2.	0.898
ENSPREP00000032789	nme3	ENSPREP00000032789	ENSPREP00000022314	RIBORED_LARGE domain-containing protein.	Nucleoside diphosphate kinase.	0.945
ENSPREP00000032789	nme6	ENSPREP00000032789	ENSPREP00000028503	RIBORED_LARGE domain-containing protein.	Nucleoside diphosphate kinase.	0.945
ENSPREP00000032789	nme7	ENSPREP00000032789	ENSPREP00000025049	RIBORED_LARGE domain-containing protein.	Nucleoside diphosphate kinase 7; Belongs to the NDK family.	0.945
ENSPREP00000032789	rrm2	ENSPREP00000032789	ENSPREP00000021751	RIBORED_LARGE domain-containing protein.	Ribonucleotide reductase M2 polypeptide.	0.989
ENSPREP00000032789	rrm2b	ENSPREP00000032789	ENSPREP00000012575	RIBORED_LARGE domain-containing protein.	Ribonucleotide reductase M2 b.	0.997
LOC103469013	ENSPREP00000032789	ENSPREP00000017608	ENSPREP00000032789	NDK domain-containing protein; Belongs to the NDK family.	RIBORED_LARGE domain-containing protein.	0.945
LOC103469013	LOC103469155	ENSPREP00000017608	ENSPREP00000024280	NDK domain-containing protein; Belongs to the NDK family.	Nucleoside diphosphate kinase.	0.929
LOC103469013	LOC103469615	ENSPREP00000017608	ENSPREP00000019751	NDK domain-containing protein; Belongs to the NDK family.	Ectonucleoside triphosphate diphosphohydrolase 2a, tandem duplicate 2; Belongs to the GDA1/CD39 NTPase family.	0.902
LOC103469013	LOC103482172	ENSPREP00000017608	ENSPREP00000006159	NDK domain-containing protein; Belongs to the NDK family.	Nucleoside diphosphate kinase.	0.901