(11 nodes) UTP metabolic process, and UMP kinase activity network (Poecilia reticulata)

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Your Input:
	RRM1	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (795 aa)
	LOC103482172	Nucleoside diphosphate kinase. (153 aa)
	cmpk1	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (216 aa)
	ak3	GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (223 aa)
	rrm2b	Ribonucleotide reductase M2 b. (354 aa)
	LOC103469013	NDK domain-containing protein; Belongs to the NDK family. (149 aa)
	LOC103469615	Ectonucleoside triphosphate diphosphohydrolase 2a, tandem duplicate 2; Belongs to the GDA1/CD39 NTPase family. (493 aa)
	nme3	Nucleoside diphosphate kinase. (180 aa)
	LOC103469155	Nucleoside diphosphate kinase. (236 aa)
	nme7	Nucleoside diphosphate kinase 7; Belongs to the NDK family. (379 aa)
	cmpk2	Cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial. (417 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC103469013	LOC103469155	ENSPREP00000017608	ENSPREP00000024280	NDK domain-containing protein; Belongs to the NDK family.	Nucleoside diphosphate kinase.	0.929
LOC103469013	LOC103469615	ENSPREP00000017608	ENSPREP00000019751	NDK domain-containing protein; Belongs to the NDK family.	Ectonucleoside triphosphate diphosphohydrolase 2a, tandem duplicate 2; Belongs to the GDA1/CD39 NTPase family.	0.902
LOC103469013	LOC103482172	ENSPREP00000017608	ENSPREP00000006159	NDK domain-containing protein; Belongs to the NDK family.	Nucleoside diphosphate kinase.	0.901
LOC103469013	RRM1	ENSPREP00000017608	ENSPREP00000000958	NDK domain-containing protein; Belongs to the NDK family.	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	0.945
LOC103469013	ak3	ENSPREP00000017608	ENSPREP00000011839	NDK domain-containing protein; Belongs to the NDK family.	GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.	0.941
LOC103469013	cmpk1	ENSPREP00000017608	ENSPREP00000010242	NDK domain-containing protein; Belongs to the NDK family.	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	0.939
LOC103469013	cmpk2	ENSPREP00000017608	ENSPREP00000031600	NDK domain-containing protein; Belongs to the NDK family.	Cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial.	0.947
LOC103469013	nme3	ENSPREP00000017608	ENSPREP00000022314	NDK domain-containing protein; Belongs to the NDK family.	Nucleoside diphosphate kinase.	0.902
LOC103469013	nme7	ENSPREP00000017608	ENSPREP00000025049	NDK domain-containing protein; Belongs to the NDK family.	Nucleoside diphosphate kinase 7; Belongs to the NDK family.	0.910
LOC103469013	rrm2b	ENSPREP00000017608	ENSPREP00000012575	NDK domain-containing protein; Belongs to the NDK family.	Ribonucleotide reductase M2 b.	0.938
LOC103469155	LOC103469013	ENSPREP00000024280	ENSPREP00000017608	Nucleoside diphosphate kinase.	NDK domain-containing protein; Belongs to the NDK family.	0.929
LOC103469155	LOC103469615	ENSPREP00000024280	ENSPREP00000019751	Nucleoside diphosphate kinase.	Ectonucleoside triphosphate diphosphohydrolase 2a, tandem duplicate 2; Belongs to the GDA1/CD39 NTPase family.	0.904
LOC103469155	LOC103482172	ENSPREP00000024280	ENSPREP00000006159	Nucleoside diphosphate kinase.	Nucleoside diphosphate kinase.	0.929
LOC103469155	RRM1	ENSPREP00000024280	ENSPREP00000000958	Nucleoside diphosphate kinase.	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	0.945
LOC103469155	ak3	ENSPREP00000024280	ENSPREP00000011839	Nucleoside diphosphate kinase.	GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.	0.954
LOC103469155	cmpk1	ENSPREP00000024280	ENSPREP00000010242	Nucleoside diphosphate kinase.	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	0.953
LOC103469155	cmpk2	ENSPREP00000024280	ENSPREP00000031600	Nucleoside diphosphate kinase.	Cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial.	0.952
LOC103469155	nme3	ENSPREP00000024280	ENSPREP00000022314	Nucleoside diphosphate kinase.	Nucleoside diphosphate kinase.	0.929
LOC103469155	nme7	ENSPREP00000024280	ENSPREP00000025049	Nucleoside diphosphate kinase.	Nucleoside diphosphate kinase 7; Belongs to the NDK family.	0.917
LOC103469155	rrm2b	ENSPREP00000024280	ENSPREP00000012575	Nucleoside diphosphate kinase.	Ribonucleotide reductase M2 b.	0.938