(12 nodes) Uniplex complex, and Prohibitin network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103467247	Mitochondrial calcium uptake family, member 3a. (526 aa)
	afg3l2	AFG3-like AAA ATPase 2. (946 aa)
	MCUB	Mitochondrial calcium uniporter dominant negative beta subunit. (336 aa)
	ENSPREP00000006614	Prohibitin. (84 aa)
	phb	Prohibitin. (271 aa)
	micu2	Mitochondrial calcium uptake 2. (391 aa)
	LOC103468189	Single-pass membrane protein with aspartate-rich tail 1b. (99 aa)
	LOC103468431	Single-pass membrane protein with aspartate-rich tail 1a. (98 aa)
	LOC103470958	Mitochondrial calcium uptake family, member 3b. (460 aa)
	spg7	SPG7 matrix AAA peptidase subunit, paraplegin. (819 aa)
	mcu	Mitochondrial calcium uniporter. (376 aa)
	micu1	Mitochondrial calcium uptake 1. (484 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000006614	LOC103467247	ENSPREP00000006614	ENSPREP00000000360	Prohibitin.	Mitochondrial calcium uptake family, member 3a.	0.498
ENSPREP00000006614	LOC103468189	ENSPREP00000006614	ENSPREP00000022984	Prohibitin.	Single-pass membrane protein with aspartate-rich tail 1b.	0.539
ENSPREP00000006614	LOC103468431	ENSPREP00000006614	ENSPREP00000024495	Prohibitin.	Single-pass membrane protein with aspartate-rich tail 1a.	0.539
ENSPREP00000006614	LOC103470958	ENSPREP00000006614	ENSPREP00000032715	Prohibitin.	Mitochondrial calcium uptake family, member 3b.	0.498
ENSPREP00000006614	MCUB	ENSPREP00000006614	ENSPREP00000003445	Prohibitin.	Mitochondrial calcium uniporter dominant negative beta subunit.	0.604
ENSPREP00000006614	afg3l2	ENSPREP00000006614	ENSPREP00000002025	Prohibitin.	AFG3-like AAA ATPase 2.	0.764
ENSPREP00000006614	mcu	ENSPREP00000006614	ENSPREP00000034221	Prohibitin.	Mitochondrial calcium uniporter.	0.604
ENSPREP00000006614	micu1	ENSPREP00000006614	ENSPREP00000034234	Prohibitin.	Mitochondrial calcium uptake 1.	0.803
ENSPREP00000006614	micu2	ENSPREP00000006614	ENSPREP00000017334	Prohibitin.	Mitochondrial calcium uptake 2.	0.777
ENSPREP00000006614	phb	ENSPREP00000006614	ENSPREP00000012361	Prohibitin.	Prohibitin.	0.995
ENSPREP00000006614	spg7	ENSPREP00000006614	ENSPREP00000033343	Prohibitin.	SPG7 matrix AAA peptidase subunit, paraplegin.	0.843
LOC103467247	ENSPREP00000006614	ENSPREP00000000360	ENSPREP00000006614	Mitochondrial calcium uptake family, member 3a.	Prohibitin.	0.498
LOC103467247	LOC103468189	ENSPREP00000000360	ENSPREP00000022984	Mitochondrial calcium uptake family, member 3a.	Single-pass membrane protein with aspartate-rich tail 1b.	0.714
LOC103467247	LOC103468431	ENSPREP00000000360	ENSPREP00000024495	Mitochondrial calcium uptake family, member 3a.	Single-pass membrane protein with aspartate-rich tail 1a.	0.714
LOC103467247	MCUB	ENSPREP00000000360	ENSPREP00000003445	Mitochondrial calcium uptake family, member 3a.	Mitochondrial calcium uniporter dominant negative beta subunit.	0.695
LOC103467247	afg3l2	ENSPREP00000000360	ENSPREP00000002025	Mitochondrial calcium uptake family, member 3a.	AFG3-like AAA ATPase 2.	0.422
LOC103467247	mcu	ENSPREP00000000360	ENSPREP00000034221	Mitochondrial calcium uptake family, member 3a.	Mitochondrial calcium uniporter.	0.695
LOC103467247	micu1	ENSPREP00000000360	ENSPREP00000034234	Mitochondrial calcium uptake family, member 3a.	Mitochondrial calcium uptake 1.	0.853
LOC103467247	micu2	ENSPREP00000000360	ENSPREP00000017334	Mitochondrial calcium uptake family, member 3a.	Mitochondrial calcium uptake 2.	0.697
LOC103467247	phb	ENSPREP00000000360	ENSPREP00000012361	Mitochondrial calcium uptake family, member 3a.	Prohibitin.	0.597