node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SMARCAL1 | hmces | ENSPREP00000014201 | ENSPREP00000026243 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1. | Abasic site processing protein HMCES; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA. The HMCES DNA-protein cross- link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endon [...] | 0.531 |
SMARCAL1 | primpol | ENSPREP00000014201 | ENSPREP00000007724 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1. | Primase and polymerase (DNA-directed). | 0.978 |
SMARCAL1 | rfwd3 | ENSPREP00000014201 | ENSPREP00000002352 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1. | Ring finger and WD repeat domain 3. | 0.654 |
SMARCAL1 | zranb3 | ENSPREP00000014201 | ENSPREP00000012031 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1. | Zinc finger, RAN-binding domain containing 3. | 0.568 |
hmces | SMARCAL1 | ENSPREP00000026243 | ENSPREP00000014201 | Abasic site processing protein HMCES; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA. The HMCES DNA-protein cross- link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endon [...] | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1. | 0.531 |
hmces | rfwd3 | ENSPREP00000026243 | ENSPREP00000002352 | Abasic site processing protein HMCES; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA. The HMCES DNA-protein cross- link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endon [...] | Ring finger and WD repeat domain 3. | 0.549 |
primpol | SMARCAL1 | ENSPREP00000007724 | ENSPREP00000014201 | Primase and polymerase (DNA-directed). | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1. | 0.978 |
primpol | rfwd3 | ENSPREP00000007724 | ENSPREP00000002352 | Primase and polymerase (DNA-directed). | Ring finger and WD repeat domain 3. | 0.937 |
primpol | zranb3 | ENSPREP00000007724 | ENSPREP00000012031 | Primase and polymerase (DNA-directed). | Zinc finger, RAN-binding domain containing 3. | 0.898 |
rfwd3 | SMARCAL1 | ENSPREP00000002352 | ENSPREP00000014201 | Ring finger and WD repeat domain 3. | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1. | 0.654 |
rfwd3 | hmces | ENSPREP00000002352 | ENSPREP00000026243 | Ring finger and WD repeat domain 3. | Abasic site processing protein HMCES; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA. The HMCES DNA-protein cross- link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endon [...] | 0.549 |
rfwd3 | primpol | ENSPREP00000002352 | ENSPREP00000007724 | Ring finger and WD repeat domain 3. | Primase and polymerase (DNA-directed). | 0.937 |
rfwd3 | zranb3 | ENSPREP00000002352 | ENSPREP00000012031 | Ring finger and WD repeat domain 3. | Zinc finger, RAN-binding domain containing 3. | 0.423 |
zranb3 | SMARCAL1 | ENSPREP00000012031 | ENSPREP00000014201 | Zinc finger, RAN-binding domain containing 3. | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1. | 0.568 |
zranb3 | primpol | ENSPREP00000012031 | ENSPREP00000007724 | Zinc finger, RAN-binding domain containing 3. | Primase and polymerase (DNA-directed). | 0.898 |
zranb3 | rfwd3 | ENSPREP00000012031 | ENSPREP00000002352 | Zinc finger, RAN-binding domain containing 3. | Ring finger and WD repeat domain 3. | 0.423 |