STRINGSTRING
PLK1 PLK1 mad1l1 mad1l1 ska3 ska3 ENSPREP00000001121 ENSPREP00000001121 anapc13 anapc13 LOC103464955 LOC103464955 ENSPREP00000001592 ENSPREP00000001592 ENSPREP00000001633 ENSPREP00000001633 LOC103466812 LOC103466812 anapc16 anapc16 ccnd1 ccnd1 kif2c kif2c smc4 smc4 anapc1 anapc1 fbxo5 fbxo5 LOC103477709 LOC103477709 shcbp1 shcbp1 anapc10 anapc10 ccne1 ccne1 cdc20 cdc20 cdk6 cdk6 kif2a kif2a ccnj ccnj intu intu anapc11 anapc11 fam72a fam72a ENSPREP00000005245 ENSPREP00000005245 kif21a kif21a wee1 wee1 ccnjl ccnjl LOC103465183 LOC103465183 cdk17 cdk17 Ccnd3 Ccnd3 dlgap5 dlgap5 ENSPREP00000007590 ENSPREP00000007590 LOC103479019 LOC103479019 ccng1 ccng1 anapc2 anapc2 cdc16 cdc16 LOC103474790 LOC103474790 cdkn2b cdkn2b skp2 skp2 LOC103471520 LOC103471520 ska1 ska1 melk melk LOC103460746 LOC103460746 CDC25B CDC25B cdk1 cdk1 ccna2 ccna2 bub3 bub3 kank2 kank2 nek2 nek2 ENSPREP00000011364 ENSPREP00000011364 KIF21A KIF21A KIF23 KIF23 CCNG2 CCNG2 ube2s ube2s ncapg ncapg ncapg2 ncapg2 aurka aurka tpx2 tpx2 LOC103482274 LOC103482274 LOC103469340 LOC103469340 CCNO CCNO bicral bicral ENSPREP00000013852 ENSPREP00000013852 kif19 kif19 LOC103459498 LOC103459498 cdca8 cdca8 eml5 eml5 ccnb3 ccnb3 ENSPREP00000015401 ENSPREP00000015401 zwilch zwilch cdk14 cdk14 ENSPREP00000015823 ENSPREP00000015823 cul1 cul1 ncapd2 ncapd2 LOC103479248 LOC103479248 LOC103466529 LOC103466529 LOC103469079 LOC103469079 clg4h1orf112 clg4h1orf112 bora bora ccna1 ccna1 LOC103463560 LOC103463560 LOC103465909 LOC103465909 kank3 kank3 smc2 smc2 kif11 kif11 incenp incenp pttg1 pttg1 LOC103465931 LOC103465931 cdca3 cdca3 cdc27 cdc27 ect2 ect2 LOC103470687 LOC103470687 LOC103460235 LOC103460235 ube2e1 ube2e1 LOC103471961 LOC103471961 ENSPREP00000020403 ENSPREP00000020403 Kif17 Kif17 cdkn2d cdkn2d LOC103471497 LOC103471497 Bub1 Bub1 ENSPREP00000021048 ENSPREP00000021048 cdk2 cdk2 LOC103466461 LOC103466461 kifbp kifbp ENSPREP00000021805 ENSPREP00000021805 cdk4 cdk4 ENSPREP00000022311 ENSPREP00000022311 ENSPREP00000022362 ENSPREP00000022362 ENSPREP00000022428 ENSPREP00000022428 ttk ttk ncaph ncaph ube2c ube2c LOC103459684 LOC103459684 ENSPREP00000023746 ENSPREP00000023746 anapc7 anapc7 bicra bicra eml1 eml1 espl1 espl1 ENSPREP00000024188 ENSPREP00000024188 pbk pbk Ska2 Ska2 cdc26 cdc26 CKS2 CKS2 fam89a fam89a chek1 chek1 LOC103460459 LOC103460459 FZR1 FZR1 cdkn3 cdkn3 LOC103473261 LOC103473261 LOC103465434 LOC103465434 ccne2 ccne2 ENSPREP00000027387 ENSPREP00000027387 anapc4 anapc4 LOC103467457 LOC103467457 nusap1 nusap1 LOC103475145 LOC103475145 LOC103464190 LOC103464190 anapc15 anapc15 ENSPREP00000028777 ENSPREP00000028777 cks1b cks1b LOC103473919 LOC103473919 ENSPREP00000029492 ENSPREP00000029492 LOC103481969 LOC103481969 ccnb1 ccnb1 pclaf pclaf ncapd3 ncapd3 anapc5 anapc5 wee2 wee2 kntc1 kntc1 mad2l1 mad2l1 bub1b bub1b foxm1 foxm1 racgap1 racgap1 KIF18A KIF18A cep55 cep55 LOC103463131 LOC103463131 LOC103459164 LOC103459164 kif22 kif22 cdc23 cdc23 kif20a kif20a
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PLK1Serine/threonine-protein kinase PLK. (581 aa)
mad1l1Mitotic arrest deficient 1 like 1. (719 aa)
ska3Spindle and kinetochore associated complex subunit 3. (523 aa)
ENSPREP00000001121Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (364 aa)
anapc13Anaphase promoting complex subunit 13. (74 aa)
LOC103464955Uncharacterized protein. (628 aa)
ENSPREP00000001592Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (188 aa)
ENSPREP00000001633Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (164 aa)
LOC103466812Cyclin D2, a; Belongs to the cyclin family. (355 aa)
anapc16Anaphase promoting complex subunit 16. (108 aa)
ccnd1Cyclin D1; Belongs to the cyclin family. (292 aa)
kif2cKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (711 aa)
smc4Structural maintenance of chromosomes 4. (1155 aa)
anapc1Anaphase promoting complex subunit 1. (1878 aa)
fbxo5F-box protein 5. (376 aa)
LOC103477709Ubiquitin-conjugating enzyme E2E 2; Belongs to the ubiquitin-conjugating enzyme family. (201 aa)
shcbp1SHC SH2-domain binding protein 1. (685 aa)
anapc10Anaphase promoting complex subunit 10. (184 aa)
ccne1Cyclin E1; Belongs to the cyclin family. (434 aa)
cdc20Cell division cycle 20 homolog. (555 aa)
cdk6Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. (325 aa)
kif2aKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (755 aa)
ccnjCyclin J; Belongs to the cyclin family. (354 aa)
intuInturned planar cell polarity protein. (962 aa)
anapc11APC11 anaphase promoting complex subunit 11 homolog (yeast). (84 aa)
fam72aFamily with sequence similarity 72 member B. (149 aa)
ENSPREP00000005245Uncharacterized protein. (189 aa)
kif21aKinesin family member 21A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1588 aa)
wee1Wee1-like protein kinase. (620 aa)
ccnjlCyclin J-like; Belongs to the cyclin family. (422 aa)
LOC103465183Cyclin-dependent kinase inhibitor 1A. (156 aa)
cdk17Cyclin dependent kinase 17. (521 aa)
Ccnd3Cyclin D3; Belongs to the cyclin family. (198 aa)
dlgap5Discs, large (Drosophila) homolog-associated protein 5. (827 aa)
ENSPREP00000007590Cyclin I family, member 2; Belongs to the cyclin family. (339 aa)
LOC103479019Fizzy/cell division cycle 20 related 1b. (396 aa)
ccng1CYCLIN domain-containing protein; Belongs to the cyclin family. (297 aa)
anapc2Anaphase promoting complex subunit 2; Belongs to the cullin family. (742 aa)
cdc16Cell division cycle 16 homolog (S. cerevisiae). (618 aa)
LOC103474790Cyclin N-terminal domain containing 2; Belongs to the cyclin family. (355 aa)
cdkn2bCyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4). (126 aa)
skp2F-box domain-containing protein. (426 aa)
LOC103471520Cyclin-dependent kinase 15. (515 aa)
ska1Uncharacterized protein. (242 aa)
melkNon-specific serine/threonine protein kinase. (601 aa)
LOC103460746Si:ch1073-416j23.1. (674 aa)
CDC25BCell division cycle 25B. (383 aa)
cdk1Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (308 aa)
ccna2Cyclin A2; Belongs to the cyclin family. (434 aa)
bub3BUB3 mitotic checkpoint protein. (326 aa)
kank2KN motif and ankyrin repeat domains 2. (1003 aa)
nek2NIMA-related kinase 2. (352 aa)
ENSPREP00000011364Kinesin family member 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1074 aa)
KIF21AKinesin family member 21A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1596 aa)
KIF23Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (854 aa)
CCNG2Cyclin G2; Belongs to the cyclin family. (331 aa)
ube2sUbiquitin-conjugating enzyme E2S; Belongs to the ubiquitin-conjugating enzyme family. (203 aa)
ncapgNon-SMC condensin I complex, subunit G. (1013 aa)
ncapg2Non-SMC condensin II complex, subunit G2. (1075 aa)
aurkaAurora kinase A; Belongs to the protein kinase superfamily. (427 aa)
tpx2TPX2 microtubule nucleation factor. (657 aa)
LOC103482274Zgc:56231; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (531 aa)
LOC103469340Cyclin-dependent kinase 21; Belongs to the protein kinase superfamily. (289 aa)
CCNOCyclin O; Belongs to the cyclin family. (301 aa)
bicralBRD4 interacting chromatin remodeling complex associated protein like. (779 aa)
ENSPREP00000013852Uncharacterized protein. (148 aa)
kif19Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (848 aa)
LOC103459498Cyclin-dependent kinase inhibitor 1D. (179 aa)
cdca8Cell division cycle associated 8. (234 aa)
eml5EMAP like 5. (1941 aa)
ccnb3Cyclin B3; Belongs to the cyclin family. (475 aa)
ENSPREP00000015401CENP-F_N domain-containing protein. (75 aa)
zwilchZwilch kinetochore protein. (594 aa)
cdk14Cyclin-dependent kinase 14; Belongs to the protein kinase superfamily. (423 aa)
ENSPREP00000015823Rho-GAP domain-containing protein. (307 aa)
cul1Cullin 1b; Belongs to the cullin family. (776 aa)
ncapd2Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. (1369 aa)
LOC103479248Uncharacterized protein. (537 aa)
LOC103466529Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (894 aa)
LOC103469079Cyclin Dx; Belongs to the cyclin family. (295 aa)
clg4h1orf112Si:dkey-97o5.1. (921 aa)
boraBora aurora kinase A activator. (556 aa)
ccna1Cyclin A1; Belongs to the cyclin family. (402 aa)
LOC103463560Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (76 aa)
LOC103465909Cyclin-dependent kinase inhibitor 1Bb. (194 aa)
kank3KN motif and ankyrin repeat domains 3. (988 aa)
smc2Structural maintenance of chromosomes protein. (1200 aa)
kif11Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (945 aa)
incenpUncharacterized protein. (755 aa)
pttg1Uncharacterized protein. (177 aa)
LOC103465931Cyclin-dependent kinase inhibitor 1Cb. (217 aa)
cdca3Si:ch211-69g19.2. (419 aa)
cdc27Cell division cycle 27. (803 aa)
ect2Epithelial cell transforming 2. (1097 aa)
LOC103470687Cytoskeleton associated protein 2-like. (742 aa)
LOC103460235Cyclin-dependent kinase 16; Belongs to the protein kinase superfamily. (392 aa)
ube2e1Ubiquitin-conjugating enzyme E2E 1; Belongs to the ubiquitin-conjugating enzyme family. (195 aa)
LOC103471961UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (206 aa)
ENSPREP00000020403Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (157 aa)
Kif17Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (241 aa)
cdkn2dCyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4). (164 aa)
LOC103471497Aurora kinase B; Belongs to the protein kinase superfamily. (350 aa)
Bub1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (210 aa)
ENSPREP00000021048BUB1 N-terminal domain-containing protein. (264 aa)
cdk2Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa)
LOC103466461Protein regulator of cytokinesis 1a. (595 aa)
kifbpKif1 binding protein. (639 aa)
ENSPREP00000021805Protein kinase domain-containing protein. (70 aa)
cdk4Cyclin-dependent kinase 4. (228 aa)
ENSPREP00000022311Transforming, acidic coiled-coil containing protein 3. (781 aa)
ENSPREP00000022362Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (287 aa)
ENSPREP00000022428HMMR_C domain-containing protein. (656 aa)
ttkTtk protein kinase. (996 aa)
ncaphCondensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. (696 aa)
ube2cUbiquitin-conjugating enzyme E2C; Belongs to the ubiquitin-conjugating enzyme family. (183 aa)
LOC103459684Cyclin dependent kinase 17. (528 aa)
ENSPREP00000023746Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (323 aa)
anapc7Anaphase promoting complex subunit 7. (565 aa)
bicraBRD4 interacting chromatin remodeling complex associated protein. (1687 aa)
eml1EMAP like 1. (640 aa)
espl1Extra spindle pole bodies like 1, separase. (2165 aa)
ENSPREP00000024188Uncharacterized protein. (108 aa)
pbkPDZ binding kinase. (340 aa)
Ska2SKA2 domain-containing protein. (148 aa)
cdc26Uncharacterized protein. (62 aa)
CKS2Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (76 aa)
fam89aFamily with sequence similarity 89 member A. (177 aa)
chek1Checkpoint kinase 1; Belongs to the protein kinase superfamily. (478 aa)
LOC103460459Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (932 aa)
FZR1Fizzy/cell division cycle 20 related 1a. (470 aa)
cdkn3Cyclin-dependent kinase inhibitor 3; May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues. (197 aa)
LOC103473261Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (730 aa)
LOC103465434Cyclin dependent kinase 18; Belongs to the protein kinase superfamily. (493 aa)
ccne2Cyclin E2; Belongs to the cyclin family. (394 aa)
ENSPREP00000027387PP1-binding domain-containing protein. (588 aa)
anapc4Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (802 aa)
LOC103467457Protein kinase domain-containing protein. (548 aa)
nusap1Nucleolar and spindle associated protein 1. (434 aa)
LOC103475145EMAP like 2. (623 aa)
LOC103464190ANK_REP_REGION domain-containing protein. (161 aa)
anapc15Anaphase promoting complex subunit 15. (122 aa)
ENSPREP00000028777Non-SMC condensin II complex, subunit H2. (419 aa)
cks1bCyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (78 aa)
LOC103473919Cyclin G2; Belongs to the cyclin family. (330 aa)
ENSPREP00000029492ANK_REP_REGION domain-containing protein. (376 aa)
LOC103481969Baculoviral IAP repeat containing 5a. (157 aa)
ccnb1Cyclin B1; Belongs to the cyclin family. (401 aa)
pclafPCNA clamp associated factor. (115 aa)
ncapd3Condensin-2 complex subunit D3; Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis. (1311 aa)
anapc5Anaphase promoting complex subunit 5. (773 aa)
wee2Wee1-like protein kinase. (527 aa)
kntc1Kinetochore associated 1. (2067 aa)
mad2l1MAD2 mitotic arrest deficient-like 1 (yeast). (202 aa)
bub1bBUB1 mitotic checkpoint serine/threonine kinase Bb. (427 aa)
foxm1Forkhead box M1. (659 aa)
racgap1Rac GTPase activating protein 1. (630 aa)
KIF18AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (909 aa)
cep55Centrosomal protein 55 like. (500 aa)
LOC103463131Abnormal spindle microtubule assembly. (2866 aa)
LOC103459164Cyclin D2, b; Belongs to the cyclin family. (294 aa)
kif22Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (626 aa)
cdc23CDC23 (cell division cycle 23, yeast, homolog). (575 aa)
kif20aKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (885 aa)
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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