(25 nodes) Proteasome network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	psmd12	Proteasome 26S subunit, non-ATPase 12. (456 aa)
	psmc6	Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (389 aa)
	psma5	Proteasome subunit alpha type. (253 aa)
	psmb3	Proteasome subunit beta. (202 aa)
	psma3	Proteasome subunit alpha type. (253 aa)
	psma1	Proteasome endopeptidase complex. (276 aa)
	LOC103479568	Proteasome subunit alpha type. (251 aa)
	psma4	Proteasome subunit alpha type. (261 aa)
	psmd1	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (952 aa)
	usp14	Ubiquitin carboxyl-terminal hydrolase. (416 aa)
	psmc3	Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (427 aa)
	psmb1	Proteasome subunit beta. (241 aa)
	psmb2	Proteasome subunit beta. (199 aa)
	psmd2	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (906 aa)
	psmd3	Proteasome 26S subunit, non-ATPase 3. (527 aa)
	psmc2	Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (438 aa)
	psma2	Proteasome endopeptidase complex. (164 aa)
	psmd7	Proteasome 26S subunit, non-ATPase 7. (330 aa)
	psmd8	Proteasome 26S subunit, non-ATPase 8. (278 aa)
	psmc4	Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (421 aa)
	psmd13	Proteasome 26S subunit, non-ATPase 13. (258 aa)
	psmc1	Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family. (440 aa)
	psmd6	Proteasome 26S subunit, non-ATPase 6. (369 aa)
	psmd14	Proteasome 26S subunit, non-ATPase 14. (310 aa)
	psmc5	Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (408 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC103479568	psma1	ENSPREP00000006668	ENSPREP00000006260	Proteasome subunit alpha type.	Proteasome endopeptidase complex.	0.999
LOC103479568	psma2	ENSPREP00000006668	ENSPREP00000020614	Proteasome subunit alpha type.	Proteasome endopeptidase complex.	0.999
LOC103479568	psma3	ENSPREP00000006668	ENSPREP00000005555	Proteasome subunit alpha type.	Proteasome subunit alpha type.	0.999
LOC103479568	psma4	ENSPREP00000006668	ENSPREP00000008662	Proteasome subunit alpha type.	Proteasome subunit alpha type.	0.999
LOC103479568	psma5	ENSPREP00000006668	ENSPREP00000004553	Proteasome subunit alpha type.	Proteasome subunit alpha type.	0.999
LOC103479568	psmb1	ENSPREP00000006668	ENSPREP00000014978	Proteasome subunit alpha type.	Proteasome subunit beta.	0.999
LOC103479568	psmb2	ENSPREP00000006668	ENSPREP00000015105	Proteasome subunit alpha type.	Proteasome subunit beta.	0.999
LOC103479568	psmb3	ENSPREP00000006668	ENSPREP00000004897	Proteasome subunit alpha type.	Proteasome subunit beta.	0.999
LOC103479568	psmc1	ENSPREP00000006668	ENSPREP00000027392	Proteasome subunit alpha type.	Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family.	0.999
LOC103479568	psmc2	ENSPREP00000006668	ENSPREP00000020024	Proteasome subunit alpha type.	Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family.	0.998
LOC103479568	psmc3	ENSPREP00000006668	ENSPREP00000014953	Proteasome subunit alpha type.	Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family.	0.994
LOC103479568	psmc4	ENSPREP00000006668	ENSPREP00000024497	Proteasome subunit alpha type.	Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family.	0.998
LOC103479568	psmc5	ENSPREP00000006668	ENSPREP00000033872	Proteasome subunit alpha type.	Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family.	0.992
LOC103479568	psmc6	ENSPREP00000006668	ENSPREP00000001014	Proteasome subunit alpha type.	Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family.	0.997
LOC103479568	psmd1	ENSPREP00000006668	ENSPREP00000009654	Proteasome subunit alpha type.	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.	0.994
LOC103479568	psmd12	ENSPREP00000006668	ENSPREP00000000315	Proteasome subunit alpha type.	Proteasome 26S subunit, non-ATPase 12.	0.997
LOC103479568	psmd13	ENSPREP00000006668	ENSPREP00000025101	Proteasome subunit alpha type.	Proteasome 26S subunit, non-ATPase 13.	0.994
LOC103479568	psmd14	ENSPREP00000006668	ENSPREP00000029743	Proteasome subunit alpha type.	Proteasome 26S subunit, non-ATPase 14.	0.997
LOC103479568	psmd2	ENSPREP00000006668	ENSPREP00000015350	Proteasome subunit alpha type.	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.	0.995
LOC103479568	psmd3	ENSPREP00000006668	ENSPREP00000017310	Proteasome subunit alpha type.	Proteasome 26S subunit, non-ATPase 3.	0.981