(13 nodes) Protein deneddylation, and Cul4A-RING E3 ubiquitin ligase complex network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ddb1	Damage-specific DNA binding protein 1. (1102 aa)
	gps1	G protein pathway suppressor 1. (486 aa)
	cops2	COP9 signalosome subunit 2. (448 aa)
	ddb2	Damage-specific DNA binding protein 2. (490 aa)
	cops7a	COP9 constitutive photomorphogenic homolog subunit 7A. (268 aa)
	COPS6	COP9 signalosome subunit 6. (316 aa)
	ENSPREP00000020872	Uncharacterized protein. (76 aa)
	ercc8	Excision repair cross-complementation group 8. (401 aa)
	cops4	COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis). (406 aa)
	ppp1r42	Protein phosphatase 1, regulatory subunit 42. (291 aa)
	cops5	COP9 signalosome subunit 5. (338 aa)
	cul4a	Cullin 4A; Belongs to the cullin family. (591 aa)
	cops3	COP9 signalosome subunit 3. (423 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
COPS6	ENSPREP00000020872	ENSPREP00000020740	ENSPREP00000020872	COP9 signalosome subunit 6.	Uncharacterized protein.	0.997
COPS6	cops2	ENSPREP00000020740	ENSPREP00000012728	COP9 signalosome subunit 6.	COP9 signalosome subunit 2.	0.999
COPS6	cops3	ENSPREP00000020740	ENSPREP00000032020	COP9 signalosome subunit 6.	COP9 signalosome subunit 3.	0.999
COPS6	cops4	ENSPREP00000020740	ENSPREP00000026999	COP9 signalosome subunit 6.	COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis).	0.999
COPS6	cops5	ENSPREP00000020740	ENSPREP00000029721	COP9 signalosome subunit 6.	COP9 signalosome subunit 5.	0.998
COPS6	cops7a	ENSPREP00000020740	ENSPREP00000018791	COP9 signalosome subunit 6.	COP9 constitutive photomorphogenic homolog subunit 7A.	0.996
COPS6	cul4a	ENSPREP00000020740	ENSPREP00000031714	COP9 signalosome subunit 6.	Cullin 4A; Belongs to the cullin family.	0.898
COPS6	ddb1	ENSPREP00000020740	ENSPREP00000006475	COP9 signalosome subunit 6.	Damage-specific DNA binding protein 1.	0.902
COPS6	ddb2	ENSPREP00000020740	ENSPREP00000016461	COP9 signalosome subunit 6.	Damage-specific DNA binding protein 2.	0.880
COPS6	ercc8	ENSPREP00000020740	ENSPREP00000026087	COP9 signalosome subunit 6.	Excision repair cross-complementation group 8.	0.768
COPS6	gps1	ENSPREP00000020740	ENSPREP00000008916	COP9 signalosome subunit 6.	G protein pathway suppressor 1.	0.999
COPS6	ppp1r42	ENSPREP00000020740	ENSPREP00000029694	COP9 signalosome subunit 6.	Protein phosphatase 1, regulatory subunit 42.	0.982
ENSPREP00000020872	COPS6	ENSPREP00000020872	ENSPREP00000020740	Uncharacterized protein.	COP9 signalosome subunit 6.	0.997
ENSPREP00000020872	cops2	ENSPREP00000020872	ENSPREP00000012728	Uncharacterized protein.	COP9 signalosome subunit 2.	0.999
ENSPREP00000020872	cops3	ENSPREP00000020872	ENSPREP00000032020	Uncharacterized protein.	COP9 signalosome subunit 3.	0.999
ENSPREP00000020872	cops4	ENSPREP00000020872	ENSPREP00000026999	Uncharacterized protein.	COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis).	0.999
ENSPREP00000020872	cops5	ENSPREP00000020872	ENSPREP00000029721	Uncharacterized protein.	COP9 signalosome subunit 5.	0.994
ENSPREP00000020872	cops7a	ENSPREP00000020872	ENSPREP00000018791	Uncharacterized protein.	COP9 constitutive photomorphogenic homolog subunit 7A.	0.985
ENSPREP00000020872	cul4a	ENSPREP00000020872	ENSPREP00000031714	Uncharacterized protein.	Cullin 4A; Belongs to the cullin family.	0.890
ENSPREP00000020872	ddb1	ENSPREP00000020872	ENSPREP00000006475	Uncharacterized protein.	Damage-specific DNA binding protein 1.	0.881