STRINGSTRING
orc1 orc1 cdca7l cdca7l cdca7 cdca7 topbp1 topbp1 ticrr ticrr cdt1 cdt1 tipin tipin ZNF830 ZNF830 dna2 dna2 CLSPN CLSPN hus1 hus1 rad17 rad17 timeless timeless rad9b rad9b rad9a rad9a cdc6 cdc6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
orc1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (629 aa)
cdca7lCell division cycle associated 7b. (397 aa)
cdca7Cell division cycle associated 7a. (403 aa)
topbp1DNA topoisomerase II binding protein 1. (1453 aa)
ticrrTreslin_N domain-containing protein. (1692 aa)
cdt1Chromatin licensing and DNA replication factor 1. (620 aa)
tipinTIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (254 aa)
ZNF830Zinc finger protein 830. (333 aa)
dna2Uncharacterized protein. (1328 aa)
CLSPNClaspin. (1239 aa)
hus1Checkpoint protein; Belongs to the HUS1 family. (245 aa)
rad17RAD17 checkpoint clamp loader component. (705 aa)
timelessTimeless circadian clock. (1173 aa)
rad9bRAD9 checkpoint clamp component B. (442 aa)
rad9aCell cycle checkpoint control protein; Belongs to the rad9 family. (387 aa)
cdc6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (586 aa)
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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