STRINGSTRING
LOC103477783 LOC103477783 Lin28a Lin28a zc3h12a zc3h12a psma4 psma4 CNOT2 CNOT2 LOC103477773 LOC103477773 LOC103477771 LOC103477771 noct noct LOC103468198 LOC103468198 Wtip Wtip kiaa0355 kiaa0355 cnot3 cnot3 lsm14a lsm14a LOC103474855 LOC103474855 psma6 psma6 ENSPREP00000013186 ENSPREP00000013186 rc3h2 rc3h2 aicda aicda LOC103473053 LOC103473053 LIMD1 LIMD1 igf2bp2 igf2bp2 lsm1 lsm1 ENSPREP00000014507 ENSPREP00000014507 LOC103479258 LOC103479258 ago4 ago4 samd4b samd4b UPF1 UPF1 lsm4 lsm4 sqstm1 sqstm1 LOC103464680 LOC103464680 dcp2 dcp2 carhsp1 carhsp1 cnot8 cnot8 psmc2 psmc2 psma2 psma2 LOC103468018 LOC103468018 edc3 edc3 ddx6 ddx6 caprin1 caprin1 lsm2 lsm2 polr2g polr2g LOC103466382 LOC103466382 RBPMS RBPMS ybx1 ybx1 LOC103481147 LOC103481147 tnrc6b tnrc6b mex3a mex3a rc3h1 rc3h1 YTHDF1 YTHDF1 btbd2 btbd2 trim71 trim71 Top1 Top1 LOC103457804 LOC103457804 samd4a samd4a cnot1 cnot1 BTBD1 BTBD1 tnrc6a tnrc6a ythdf2 ythdf2 pan3 pan3 ythdf3 ythdf3 LOC103481169 LOC103481169 hax1 hax1 mov10 mov10 ENSPREP00000030212 ENSPREP00000030212 csdc2 csdc2 LOC103466190 LOC103466190 xrn1 xrn1 edc4 edc4 polr2d polr2d LOC103470954 LOC103470954 ENSPREP00000032886 ENSPREP00000032886 lsm3 lsm3 LOC103462434 LOC103462434 patl2 patl2 lsm6 lsm6 nanos3 nanos3 dcp1a dcp1a LOC103472876 LOC103472876 ENSPREP00000000983 ENSPREP00000000983 cnot9 cnot9 pan2 pan2 clg13h19orf54 clg13h19orf54 LOC103463886 LOC103463886 LOC103469285 LOC103469285 LOC103472224 LOC103472224 LOC103472230 LOC103472230 LOC103467732 LOC103467732 EIF4ENIF1 EIF4ENIF1 c9orf72 c9orf72 dis3l2 dis3l2 dcps dcps patl1 patl1 dcp1b dcp1b LOC103475990 LOC103475990
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC103477783Proline-rich nuclear receptor coactivator 2. (155 aa)
Lin28aCCHC-type domain-containing protein. (202 aa)
zc3h12aZinc finger CCCH-type containing 12A. (623 aa)
psma4Proteasome subunit alpha type. (261 aa)
CNOT2CCR4-NOT transcription complex subunit 2. (522 aa)
LOC103477773Argonaute RISC component 1; Belongs to the argonaute family. (858 aa)
LOC103477771Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily. (867 aa)
noctNocturnin. (445 aa)
LOC103468198Insulin-like growth factor 2 mRNA binding protein 1. (601 aa)
WtipWT1 interacting protein. (624 aa)
kiaa0355Si:ch211-79l17.1. (1091 aa)
cnot3CCR4-NOT transcription complex, subunit 3a. (894 aa)
lsm14aLSM14A mRNA processing body assembly factor b. (463 aa)
LOC103474855Proteasome endopeptidase complex. (248 aa)
psma6Proteasome subunit alpha type. (254 aa)
ENSPREP00000013186Uncharacterized protein. (199 aa)
rc3h2Ring finger and CCCH-type domains 2. (1110 aa)
aicdaActivation-induced cytidine deaminase. (211 aa)
LOC103473053Uncharacterized protein; Belongs to the argonaute family. (695 aa)
LIMD1LIM domains containing 1. (540 aa)
igf2bp2Insulin-like growth factor 2 mRNA binding protein 2a. (613 aa)
lsm1U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs. (133 aa)
ENSPREP00000014507UBA_6 domain-containing protein. (200 aa)
LOC103479258Uncharacterized protein. (1109 aa)
ago4Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily. (913 aa)
samd4bSterile alpha motif domain containing 4B. (673 aa)
UPF1UPF1 RNA helicase and ATPase. (1097 aa)
lsm4U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (188 aa)
sqstm1Sequestosome 1. (500 aa)
LOC103464680Mov10 RISC complex RNA helicase a. (992 aa)
dcp2Decapping mRNA 2. (398 aa)
carhsp1Calcium regulated heat stable protein 1. (158 aa)
cnot8CCR4-NOT transcription complex, subunit 8. (285 aa)
psmc2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (438 aa)
psma2Proteasome endopeptidase complex. (164 aa)
LOC103468018Trinucleotide repeat containing adaptor 6C2. (1547 aa)
edc3Enhancer of mRNA decapping 3 homolog (S. cerevisiae). (478 aa)
ddx6DEAD (Asp-Glu-Ala-Asp) box helicase 6; Belongs to the DEAD box helicase family. (482 aa)
caprin1Cell cycle associated protein 1b. (686 aa)
lsm2U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (93 aa)
polr2gPolymerase (RNA) II (DNA directed) polypeptide G-like. (172 aa)
LOC103466382LSM14A mRNA processing body assembly factor a. (480 aa)
RBPMSRNA binding protein, mRNA processing factor. (267 aa)
ybx1Y box binding protein 1. (299 aa)
LOC103481147TNRC6-PABC_bdg domain-containing protein. (1685 aa)
tnrc6bSi:dkey-46g23.1. (2000 aa)
mex3aRING-type domain-containing protein. (527 aa)
rc3h1Ring finger and CCCH-type domains 1b. (1119 aa)
YTHDF1YTH N6-methyladenosine RNA binding protein 1. (610 aa)
btbd2BTB (POZ) domain containing 2b. (577 aa)
trim71Tripartite motif containing 71, E3 ubiquitin protein ligase. (831 aa)
Top1DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (606 aa)
LOC103457804Proteasome subunit alpha type. (246 aa)
samd4aSterile alpha motif domain containing 4A. (774 aa)
cnot1CCR4-NOT transcription complex, subunit 1. (2246 aa)
BTBD1BTB domain containing 1. (484 aa)
tnrc6aTrinucleotide repeat containing adaptor 6A. (1659 aa)
ythdf2YTH N(6)-methyladenosine RNA binding protein 2. (639 aa)
pan3PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...] (792 aa)
ythdf3YTH N(6)-methyladenosine RNA binding protein 3. (604 aa)
LOC103481169DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (597 aa)
hax1HCLS1 associated protein X-1. (288 aa)
mov10Moloney leukemia virus 10b, tandem duplicate 1. (1011 aa)
ENSPREP00000030212Nanos homolog 2; Belongs to the nanos family. (116 aa)
csdc2Cold shock domain containing C2, RNA binding a. (157 aa)
LOC103466190CCR4-NOT transcription complex, subunit 2. (660 aa)
xrn15'-3' exoribonuclease 1. (1705 aa)
edc4Enhancer of mRNA decapping 4. (1333 aa)
polr2dPolymerase (RNA) II (DNA directed) polypeptide D. (104 aa)
LOC103470954CCR4-NOT transcription complex, subunit 7. (286 aa)
ENSPREP00000032886DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (573 aa)
lsm3U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (102 aa)
LOC103462434Cell cycle associated protein 1a. (637 aa)
patl2PAT1 homolog 2. (593 aa)
lsm6LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated. (80 aa)
nanos3Nanos homolog 3; Belongs to the nanos family. (209 aa)
dcp1aDecapping mRNA 1A. (491 aa)
LOC103472876CCR4-NOT transcription complex, subunit 3b. (938 aa)
ENSPREP00000000983Not3 domain-containing protein. (459 aa)
cnot9CCR4-NOT transcription complex subunit 9. (299 aa)
pan2PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent [...] (1211 aa)
clg13h19orf54Zgc:153119. (295 aa)
LOC103463886Nocturnin. (385 aa)
LOC103469285Trinucleotide repeat containing adaptor 6C1. (1769 aa)
LOC103472224Insulin-like growth factor 2 mRNA binding protein 3. (608 aa)
LOC103472230Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (894 aa)
LOC103467732YTH N(6)-methyladenosine RNA binding protein 1. (609 aa)
EIF4ENIF1Eukaryotic translation initiation factor 4E nuclear import factor 1. (953 aa)
c9orf72Zgc:100846. (298 aa)
dis3l2DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily. (1060 aa)
dcpsDecapping enzyme, scavenger. (330 aa)
patl1PAT1 homolog 1, processing body mRNA decay factor. (734 aa)
dcp1bDecapping mRNA 1B. (631 aa)
LOC103475990Ajuba LIM protein. (658 aa)
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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