(8 nodes) Optic vesicle morphogenesis network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	epha4	Eph receptor A4, like. (979 aa)
	LOC103479267	Uncharacterized protein. (1084 aa)
	six6	SIX homeobox 6a. (245 aa)
	efnb2	Ephrin-B2a; Belongs to the ephrin family. (313 aa)
	LOC103475931	SIX homeobox 7. (260 aa)
	Six3	SIX homeobox 3a. (341 aa)
	ENSPREP00000005246	Protein kinase domain-containing protein. (250 aa)
	LOC103481539	SIX homeobox 3b. (277 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000005246	efnb2	ENSPREP00000005246	ENSPREP00000028109	Protein kinase domain-containing protein.	Ephrin-B2a; Belongs to the ephrin family.	0.574
LOC103479267	efnb2	ENSPREP00000019054	ENSPREP00000028109	Uncharacterized protein.	Ephrin-B2a; Belongs to the ephrin family.	0.574
efnb2	ENSPREP00000005246	ENSPREP00000028109	ENSPREP00000005246	Ephrin-B2a; Belongs to the ephrin family.	Protein kinase domain-containing protein.	0.574
efnb2	LOC103479267	ENSPREP00000028109	ENSPREP00000019054	Ephrin-B2a; Belongs to the ephrin family.	Uncharacterized protein.	0.574
efnb2	epha4	ENSPREP00000028109	ENSPREP00000015956	Ephrin-B2a; Belongs to the ephrin family.	Eph receptor A4, like.	0.574
epha4	efnb2	ENSPREP00000015956	ENSPREP00000028109	Eph receptor A4, like.	Ephrin-B2a; Belongs to the ephrin family.	0.574