STRINGSTRING
ldlr ldlr MYO6 MYO6 fnbp1 fnbp1 LOC103463058 LOC103463058 fcho2 fcho2 adcy8 adcy8 ENSPREP00000030224 ENSPREP00000030224 LOC103464192 LOC103464192 eps15 eps15 ENSPREP00000026258 ENSPREP00000026258 LOC103461763 LOC103461763 ENSPREP00000024292 ENSPREP00000024292 LOC103482389 LOC103482389 ENSPREP00000015917 ENSPREP00000015917 ENSPREP00000015870 ENSPREP00000015870 ENSPREP00000015831 ENSPREP00000015831 LOC103481184 LOC103481184 LOC103459482 LOC103459482 sgip1 sgip1 itsn2 itsn2 LOC103480389 LOC103480389 cltc cltc rab35 rab35 snap91 snap91 LOC103468275 LOC103468275 LOC103457333 LOC103457333 ap2m1 ap2m1 bmpr2 bmpr2 LOC103457710 LOC103457710 LOC103479878 LOC103479878 LOC103457562 LOC103457562 LOC103459367 LOC103459367 vldlr vldlr LOC103481437 LOC103481437 ENSPREP00000002746 ENSPREP00000002746 inpp5f inpp5f LOC103462258 LOC103462258 amn amn LOC103464892 LOC103464892 LOC103474743 LOC103474743 LOC103478999 LOC103478999 lrp8 lrp8 ENSPREP00000007450 ENSPREP00000007450 LOC103460653 LOC103460653 ENSPREP00000008107 ENSPREP00000008107 LOC103471122 LOC103471122 LOC103468143 LOC103468143 LOC103470511 LOC103470511 LOC103475391 LOC103475391 aak1 aak1 DNM1L DNM1L fcho1 fcho1 atat1 atat1 cltcl1 cltcl1 LOC103473710 LOC103473710 picalm picalm LOC103457075 LOC103457075 clta clta ENSPREP00000034066 ENSPREP00000034066 ap2s1 ap2s1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ldlrLow density lipoprotein receptor a. (811 aa)
MYO6Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1214 aa)
fnbp1Formin binding protein 1b. (691 aa)
LOC103463058Low density lipoprotein receptor-related protein 8, apolipoprotein e receptor. (861 aa)
fcho2FCH domain only 2. (763 aa)
adcy8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1239 aa)
ENSPREP00000030224PID domain-containing protein. (124 aa)
LOC103464192Uncharacterized protein. (975 aa)
eps15Epidermal growth factor receptor pathway substrate 15. (1105 aa)
ENSPREP00000026258Solute carrier family 18 member 3a. (511 aa)
LOC103461763Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (871 aa)
ENSPREP00000024292SH3 domain-containing protein. (300 aa)
LOC103482389SH3-domain binding protein 4. (962 aa)
ENSPREP00000015917EH domain-containing protein. (133 aa)
ENSPREP00000015870Uncharacterized protein. (860 aa)
ENSPREP00000015831Uncharacterized protein. (499 aa)
LOC103481184Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1181 aa)
LOC103459482Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (661 aa)
sgip1SH3-domain GRB2-like (endophilin) interacting protein 1a. (938 aa)
itsn2Intersectin 2a. (1606 aa)
LOC103480389Si:ch211-200p22.4. (642 aa)
cltcClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1700 aa)
rab35RAB35, member RAS oncogene family b. (184 aa)
snap91Synaptosome associated protein 91a. (969 aa)
LOC103468275Low density lipoprotein receptor b. (906 aa)
LOC103457333SH3-domain binding protein 4a. (960 aa)
ap2m1AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (358 aa)
bmpr2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1042 aa)
LOC103457710Synaptosome associated protein 91b. (720 aa)
LOC103479878Epidermal growth factor receptor pathway substrate 15 like 1. (599 aa)
LOC103457562Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1185 aa)
LOC103459367Atypical chemokine receptor 3a; Belongs to the G-protein coupled receptor 1 family. (406 aa)
vldlrVery low density lipoprotein receptor. (830 aa)
LOC103481437Solute carrier family 18 member A3. (518 aa)
ENSPREP00000002746Sortilin. (632 aa)
inpp5fInositol polyphosphate-5-phosphatase F. (1159 aa)
LOC103462258AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (956 aa)
amnAmnion associated transmembrane protein. (498 aa)
LOC103464892Sortilin. (808 aa)
LOC103474743Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1685 aa)
LOC103478999MHD domain-containing protein. (895 aa)
lrp8Uncharacterized protein. (937 aa)
ENSPREP00000007450Uncharacterized protein. (511 aa)
LOC103460653Si:dkey-16l2.16. (209 aa)
ENSPREP00000008107Intersectin 1 (SH3 domain protein). (1107 aa)
LOC103471122Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (200 aa)
LOC103468143AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (938 aa)
LOC103470511Si:dkey-32e23.4; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (673 aa)
LOC103475391ENTH domain-containing protein. (593 aa)
aak1AP2 associated kinase 1a. (1055 aa)
DNM1LDynamin 1-like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (731 aa)
fcho1FCH domain only 1. (1193 aa)
atat1Alpha-tubulin N-acetyltransferase 1; Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dyn [...] (430 aa)
cltcl1Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1696 aa)
LOC103473710AP2 associated kinase 1b. (1079 aa)
picalmPhosphatidylinositol binding clathrin assembly protein b. (588 aa)
LOC103457075Myosin VIa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (955 aa)
cltaClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (220 aa)
ENSPREP00000034066Stonin-1; May be involved in the endocytic machinery. (659 aa)
ap2s1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (141 aa)
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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