(33 nodes) NADP metabolic process network (Poecilia reticulata)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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proteins of unknown 3D structure

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Predicted Interactions

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Your Input:
	LOC103463764	Dimethylaniline monooxygenase [N-oxide-forming]. (552 aa)
	LOC103467320	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (501 aa)
	LOC103465496	10-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. (902 aa)
	pc	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1180 aa)
	LOC103467440	Transketolase b. (626 aa)
	nudt12	Nudix (nucleoside diphosphate linked moiety X)-type motif 12. (462 aa)
	LOC103459710	10-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. (923 aa)
	pgd	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (483 aa)
	LOC103479795	NAD kinase b. (491 aa)
	LOC108166039	Flavin-containing monooxygenase. (375 aa)
	LOC103460998	Dimethylaniline monooxygenase [N-oxide-forming]. (552 aa)
	nadk	NAD kinase a. (361 aa)
	LOC103473658	Nicotinamide nucleotide transhydrogenase. (1096 aa)
	LOC103462087	Nicotinamide nucleotide transhydrogenase 2. (1014 aa)
	LOC103465119	Transketolase a. (652 aa)
	LOC103466626	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (452 aa)
	nadk2	NAD kinase 2, mitochondrial; Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+). Can use both ATP or inorganic polyphosphate as the phosphoryl donor. (433 aa)
	noct	Nocturnin. (445 aa)
	shpk	Sedoheptulokinase. (459 aa)
	rpia	Ribose 5-phosphate isomerase A (ribose 5-phosphate epimerase). (284 aa)
	LOC103467627	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (552 aa)
	LOC103462181	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (455 aa)
	pgls	6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (257 aa)
	rbks	Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (312 aa)
	taldo1	Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (339 aa)
	h6pd	Hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase). (791 aa)
	ENSPREP00000002634	Flavin-containing monooxygenase. (115 aa)
	LOC103463766	Dimethylaniline monooxygenase [N-oxide-forming]. (553 aa)
	LOC103463886	Nocturnin. (385 aa)
	nudt13	Nudix (nucleoside diphosphate linked moiety X)-type motif 13. (348 aa)
	rpe	Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (252 aa)
	LOC103463767	Dimethylaniline monooxygenase [N-oxide-forming]. (543 aa)
	TKT	Transketolase. (629 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000002634	LOC108166039	ENSPREP00000002634	ENSPREP00000020045	Flavin-containing monooxygenase.	Flavin-containing monooxygenase.	0.950
LOC103459710	LOC103465496	ENSPREP00000024924	ENSPREP00000030788	10-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.	10-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.	0.900
LOC103459710	LOC103479795	ENSPREP00000024924	ENSPREP00000020208	10-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.	NAD kinase b.	0.422
LOC103459710	h6pd	ENSPREP00000024924	ENSPREP00000006187	10-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.	Hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase).	0.438
LOC103459710	nadk	ENSPREP00000024924	ENSPREP00000015673	10-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.	NAD kinase a.	0.422
LOC103462087	LOC103473658	ENSPREP00000012612	ENSPREP00000014070	Nicotinamide nucleotide transhydrogenase 2.	Nicotinamide nucleotide transhydrogenase.	0.901
LOC103462087	LOC103479795	ENSPREP00000012612	ENSPREP00000020208	Nicotinamide nucleotide transhydrogenase 2.	NAD kinase b.	0.934
LOC103462087	nadk	ENSPREP00000012612	ENSPREP00000015673	Nicotinamide nucleotide transhydrogenase 2.	NAD kinase a.	0.934
LOC103462087	nadk2	ENSPREP00000012612	ENSPREP00000010415	Nicotinamide nucleotide transhydrogenase 2.	NAD kinase 2, mitochondrial; Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+). Can use both ATP or inorganic polyphosphate as the phosphoryl donor.	0.926
LOC103462181	LOC103479795	ENSPREP00000007277	ENSPREP00000020208	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	NAD kinase b.	0.697
LOC103462181	h6pd	ENSPREP00000007277	ENSPREP00000006187	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	Hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase).	0.665
LOC103462181	nadk	ENSPREP00000007277	ENSPREP00000015673	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	NAD kinase a.	0.697
LOC103462181	pc	ENSPREP00000007277	ENSPREP00000029584	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	0.526
LOC103462181	pgd	ENSPREP00000007277	ENSPREP00000023761	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.	0.515
LOC103462181	rpe	ENSPREP00000007277	ENSPREP00000001598	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.	0.482
LOC103462181	rpia	ENSPREP00000007277	ENSPREP00000009856	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	Ribose 5-phosphate isomerase A (ribose 5-phosphate epimerase).	0.434
LOC103462181	taldo1	ENSPREP00000007277	ENSPREP00000006695	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.	0.492
LOC103465119	LOC103467320	ENSPREP00000011752	ENSPREP00000032588	Transketolase a.	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.	0.643
LOC103465119	LOC103467440	ENSPREP00000011752	ENSPREP00000028494	Transketolase a.	Transketolase b.	0.901
LOC103465119	LOC103467627	ENSPREP00000011752	ENSPREP00000009518	Transketolase a.	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.	0.643