(23 nodes) Male meiotic nuclear division network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103464484	Forkhead box J3. (605 aa)
	tdrd12	Tudor domain containing 12. (1141 aa)
	tdrkh	Tudor and KH domain containing. (587 aa)
	asz1	Ankyrin repeat, SAM and basic leucine zipper domain containing 1. (472 aa)
	mlh1	MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli). (726 aa)
	KIF18A	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (909 aa)
	fanca	Fanconi_A_N domain-containing protein. (965 aa)
	hsf2bp	Heat shock transcription factor 2 binding protein. (339 aa)
	rec8	REC8 meiotic recombination protein b. (566 aa)
	dmc1	Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily. (343 aa)
	atm	Non-specific serine/threonine protein kinase. (3091 aa)
	meiob	Methionine sulfoxide reductase B1b. (464 aa)
	ENSPREP00000022562	Tudor domain containing 9. (993 aa)
	mlh3	MutL homolog 3 (E. coli). (1117 aa)
	ENSPREP00000033734	Uncharacterized protein. (136 aa)
	ttk	Ttk protein kinase. (996 aa)
	brdt	Bromodomain, testis-specific. (980 aa)
	rad51c	RAD51 paralog C. (377 aa)
	brca2	BRCA2 DNA repair associated. (3038 aa)
	meioc	Uncharacterized protein. (822 aa)
	ENSPREP00000033716	Fork-head domain-containing protein. (175 aa)
	tex11	Testis expressed 11. (770 aa)
	spo11	SPO11 initiator of meiotic double stranded breaks. (379 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000022562	asz1	ENSPREP00000022562	ENSPREP00000003686	Tudor domain containing 9.	Ankyrin repeat, SAM and basic leucine zipper domain containing 1.	0.645
ENSPREP00000022562	tdrd12	ENSPREP00000022562	ENSPREP00000007148	Tudor domain containing 9.	Tudor domain containing 12.	0.592
ENSPREP00000022562	tdrkh	ENSPREP00000022562	ENSPREP00000006136	Tudor domain containing 9.	Tudor and KH domain containing.	0.719
ENSPREP00000022562	tex11	ENSPREP00000022562	ENSPREP00000013731	Tudor domain containing 9.	Testis expressed 11.	0.424
ENSPREP00000033716	ENSPREP00000033734	ENSPREP00000033716	ENSPREP00000033734	Fork-head domain-containing protein.	Uncharacterized protein.	0.818
ENSPREP00000033734	ENSPREP00000033716	ENSPREP00000033734	ENSPREP00000033716	Uncharacterized protein.	Fork-head domain-containing protein.	0.818
KIF18A	brca2	ENSPREP00000033468	ENSPREP00000018297	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	BRCA2 DNA repair associated.	0.594
KIF18A	ttk	ENSPREP00000033468	ENSPREP00000022549	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Ttk protein kinase.	0.897
asz1	ENSPREP00000022562	ENSPREP00000003686	ENSPREP00000022562	Ankyrin repeat, SAM and basic leucine zipper domain containing 1.	Tudor domain containing 9.	0.645
asz1	tdrd12	ENSPREP00000003686	ENSPREP00000007148	Ankyrin repeat, SAM and basic leucine zipper domain containing 1.	Tudor domain containing 12.	0.657
asz1	tdrkh	ENSPREP00000003686	ENSPREP00000006136	Ankyrin repeat, SAM and basic leucine zipper domain containing 1.	Tudor and KH domain containing.	0.617
atm	brca2	ENSPREP00000024388	ENSPREP00000018297	Non-specific serine/threonine protein kinase.	BRCA2 DNA repair associated.	0.885
atm	dmc1	ENSPREP00000024388	ENSPREP00000025114	Non-specific serine/threonine protein kinase.	Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily.	0.832
atm	fanca	ENSPREP00000024388	ENSPREP00000030996	Non-specific serine/threonine protein kinase.	Fanconi_A_N domain-containing protein.	0.468
atm	meiob	ENSPREP00000024388	ENSPREP00000023266	Non-specific serine/threonine protein kinase.	Methionine sulfoxide reductase B1b.	0.787
atm	mlh1	ENSPREP00000024388	ENSPREP00000002003	Non-specific serine/threonine protein kinase.	MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli).	0.830
atm	mlh3	ENSPREP00000024388	ENSPREP00000014130	Non-specific serine/threonine protein kinase.	MutL homolog 3 (E. coli).	0.667
atm	rad51c	ENSPREP00000024388	ENSPREP00000019301	Non-specific serine/threonine protein kinase.	RAD51 paralog C.	0.864
atm	spo11	ENSPREP00000024388	ENSPREP00000011861	Non-specific serine/threonine protein kinase.	SPO11 initiator of meiotic double stranded breaks.	0.696
brca2	KIF18A	ENSPREP00000018297	ENSPREP00000033468	BRCA2 DNA repair associated.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.594