(77 nodes) Spermatid development network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	tmem53	Transmembrane protein 53. (297 aa)
	cfap206	Cilia and flagella associated protein 206. (626 aa)
	ccdc136	Coiled-coil domain containing 136b. (384 aa)
	ube2j1	Ubiquitin-conjugating enzyme E2, J1. (275 aa)
	piwil1	Piwi-like RNA-mediated gene silencing 1; Belongs to the argonaute family. (840 aa)
	fancg	FA complementation group G. (573 aa)
	ENSPREP00000002918	Uncharacterized protein. (267 aa)
	KLHL10	Kelch like family member 10. (590 aa)
	LOC103458658	Chemokine (C-C motif) receptor 6b; Belongs to the G-protein coupled receptor 1 family. (361 aa)
	nme5	NME/NM23 family member 5; Belongs to the NDK family. (210 aa)
	drc7	Uncharacterized protein. (720 aa)
	cep57l1	Centrosomal protein 57, like 1. (447 aa)
	LOC103476576	BTB domain-containing protein. (556 aa)
	armc2	Armadillo repeat containing 2. (583 aa)
	ENSPREP00000007296	Uncharacterized protein. (88 aa)
	aff4	AF4/FMR2 family, member 4. (1106 aa)
	ccnb1ip1	Cyclin B1 interacting protein 1. (239 aa)
	LOC103481555	Proteasome activator subunit 4b. (1781 aa)
	ABHD2	Abhydrolase domain containing 2b. (428 aa)
	LOC103475383	Adenosine deaminase domain containing 2. (624 aa)
	bbs4	Bardet-Biedl syndrome 4. (520 aa)
	adad1	Adenosine deaminase domain containing 1 (testis-specific). (536 aa)
	Pacrg	PARK2 co-regulated. (235 aa)
	mkks	McKusick-Kaufman syndrome. (576 aa)
	LOC103479101	ArfGAP with FG repeats 1b. (435 aa)
	selenof	Selenoprotein F. (154 aa)
	rsph3	Radial spoke head 3. (320 aa)
	spo11	SPO11 initiator of meiotic double stranded breaks. (379 aa)
	LOC103462096	Abhydrolase domain containing 2a. (431 aa)
	rnf8	E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (490 aa)
	LOC103474127	Uncharacterized protein. (554 aa)
	cfap69	Uncharacterized protein. (880 aa)
	cfap221	Uncharacterized protein. (808 aa)
	tbc1d20	TBC1 domain family, member 20. (397 aa)
	meioc	Uncharacterized protein. (822 aa)
	tpgs1	Uncharacterized protein. (296 aa)
	YTHDC2	YTH domain containing 2. (1418 aa)
	LOC103472476	Zgc:63863. (364 aa)
	tdrd5	Uncharacterized protein. (756 aa)
	spef2	Calponin-homology (CH) domain-containing protein. (1793 aa)
	pld6	Phospholipase D family, member 6. (211 aa)
	ENSPREP00000019710	Uncharacterized protein. (1054 aa)
	ENSPREP00000019960	WD_REPEATS_REGION domain-containing protein. (326 aa)
	brdt	Bromodomain, testis-specific. (980 aa)
	ENSPREP00000021013	Uncharacterized protein. (392 aa)
	LOC103466010	Uncharacterized protein. (281 aa)
	spag6	Sperm associated antigen 6. (542 aa)
	CCR6	C-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family. (370 aa)
	LOC103457179	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (361 aa)
	ENSPREP00000022497	G_PROTEIN_RECEP_F1_2 domain-containing protein. (160 aa)
	ENSPREP00000022516	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (369 aa)
	ENSPREP00000022535	G_PROTEIN_RECEP_F1_2 domain-containing protein. (363 aa)
	cfap65	Si:ch1073-349o24.2. (1707 aa)
	LOC103470741	Uncharacterized protein. (536 aa)
	ift81	Intraflagellar transport 81 homolog. (673 aa)
	ropn1l	Rhophilin associated tail protein 1-like. (225 aa)
	dmc1	Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily. (343 aa)
	oca2	Oculocutaneous albinism II. (840 aa)
	rec8	REC8 meiotic recombination protein b. (566 aa)
	agfg1	ArfGAP with FG repeats 1a. (635 aa)
	rsph1	Uncharacterized protein. (228 aa)
	tmf1	TATA element modulatory factor 1. (1150 aa)
	LOC103467255	BTB domain-containing protein. (577 aa)
	cib1	Calcium and integrin binding 1 (calmyrin). (195 aa)
	ENSPREP00000028080	Piwi domain-containing protein. (177 aa)
	Cfap44	WD_REPEATS_REGION domain-containing protein. (696 aa)
	ENSPREP00000028906	Uncharacterized protein. (557 aa)
	LOC103472707	Pygopus homolog 2 (Drosophila). (588 aa)
	sycp3	Synaptonemal complex protein 3. (245 aa)
	VPS13B	Vacuolar protein sorting 13 homolog B. (3878 aa)
	yif1b	Yip1 interacting factor homolog B (S. cerevisiae). (305 aa)
	ENSPREP00000031411	Nectin cell adhesion molecule 3b. (623 aa)
	LOC103465577	BTB domain-containing protein. (588 aa)
	ttc12	Tetratricopeptide repeat domain 12. (905 aa)
	cep57	Uncharacterized protein. (488 aa)
	psme4	Proteasome activator subunit 4a. (1850 aa)
	ttll1	Tubulin tyrosine ligase-like family, member 1. (424 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cfap44	ENSPREP00000019710	ENSPREP00000028881	ENSPREP00000019710	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.526
Cfap44	ENSPREP00000028906	ENSPREP00000028881	ENSPREP00000028906	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.939
Cfap44	ift81	ENSPREP00000028881	ENSPREP00000024120	WD_REPEATS_REGION domain-containing protein.	Intraflagellar transport 81 homolog.	0.551
ENSPREP00000019710	Cfap44	ENSPREP00000019710	ENSPREP00000028881	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.526
ENSPREP00000019710	ENSPREP00000028906	ENSPREP00000019710	ENSPREP00000028906	Uncharacterized protein.	Uncharacterized protein.	0.526
ENSPREP00000019710	drc7	ENSPREP00000019710	ENSPREP00000006787	Uncharacterized protein.	Uncharacterized protein.	0.483
ENSPREP00000019710	spef2	ENSPREP00000019710	ENSPREP00000019179	Uncharacterized protein.	Calponin-homology (CH) domain-containing protein.	0.514
ENSPREP00000019960	ift81	ENSPREP00000019960	ENSPREP00000024120	WD_REPEATS_REGION domain-containing protein.	Intraflagellar transport 81 homolog.	0.551
ENSPREP00000028080	YTHDC2	ENSPREP00000028080	ENSPREP00000017945	Piwi domain-containing protein.	YTH domain containing 2.	0.498
ENSPREP00000028080	pld6	ENSPREP00000028080	ENSPREP00000019640	Piwi domain-containing protein.	Phospholipase D family, member 6.	0.409
ENSPREP00000028080	tdrd5	ENSPREP00000028080	ENSPREP00000018045	Piwi domain-containing protein.	Uncharacterized protein.	0.754
ENSPREP00000028906	Cfap44	ENSPREP00000028906	ENSPREP00000028881	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.939
ENSPREP00000028906	ENSPREP00000019710	ENSPREP00000028906	ENSPREP00000019710	Uncharacterized protein.	Uncharacterized protein.	0.526
ENSPREP00000028906	ift81	ENSPREP00000028906	ENSPREP00000024120	Uncharacterized protein.	Intraflagellar transport 81 homolog.	0.551
ENSPREP00000031411	LOC103474127	ENSPREP00000031411	ENSPREP00000012509	Nectin cell adhesion molecule 3b.	Uncharacterized protein.	0.902
KLHL10	bbs4	ENSPREP00000004669	ENSPREP00000009421	Kelch like family member 10.	Bardet-Biedl syndrome 4.	0.630
LOC103465577	bbs4	ENSPREP00000033103	ENSPREP00000009421	BTB domain-containing protein.	Bardet-Biedl syndrome 4.	0.630
LOC103467255	bbs4	ENSPREP00000026938	ENSPREP00000009421	BTB domain-containing protein.	Bardet-Biedl syndrome 4.	0.630
LOC103474127	ENSPREP00000031411	ENSPREP00000012509	ENSPREP00000031411	Uncharacterized protein.	Nectin cell adhesion molecule 3b.	0.902
LOC103476576	bbs4	ENSPREP00000007047	ENSPREP00000009421	BTB domain-containing protein.	Bardet-Biedl syndrome 4.	0.630