(27 nodes) Body fluid secretion network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103459817	Suppressor of cytokine signaling 2. (196 aa)
	copa	Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. (1222 aa)
	LOC103462573	Cytochrome b-245, alpha polypeptide. (126 aa)
	Cav1	Uncharacterized protein. (84 aa)
	LOC103460557	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (562 aa)
	LOC103482184	Signal transducer and activator of transcription. (784 aa)
	atp7a	ATPase copper transporting alpha. (1508 aa)
	usf2	BHLH domain-containing protein. (327 aa)
	aqp1	Aquaporin 1a (Colton blood group), tandem duplicate 1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (268 aa)
	ENSPREP00000010780	Aquaporin 1a (Colton blood group), tandem duplicate 1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (176 aa)
	aprt	Adenine phosphoribosyltransferase. (180 aa)
	edn1	Endothelin 1. (207 aa)
	LOC103474147	Zgc:174895. (267 aa)
	ENSPREP00000013476	Upstream transcription factor 2, c-fos interacting. (390 aa)
	LOC103465217	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (159 aa)
	LOC103469404	Signal transducer and activator of transcription. (787 aa)
	npr3	Natriuretic peptide receptor 3. (504 aa)
	pam	Peptidylglycine alpha-amidating monooxygenase. (947 aa)
	ENSPREP00000022754	Vesicle-associated membrane protein 8 (endobrevin). (118 aa)
	ENSPREP00000022805	V-SNARE coiled-coil homology domain-containing protein. (116 aa)
	atp7b	ATPase copper transporting beta. (1315 aa)
	ENSPREP00000026492	SEFIR domain-containing protein. (109 aa)
	ucn	Urotensin 1. (147 aa)
	atg5	Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
	traf3ip2	SEFIR domain-containing protein. (418 aa)
	LOC103473964	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (506 aa)
	LOC103467308	Signal transducer and activator of transcription. (665 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000026492	traf3ip2	ENSPREP00000026492	ENSPREP00000030465	SEFIR domain-containing protein.	SEFIR domain-containing protein.	0.900
LOC103460557	LOC103473964	ENSPREP00000004169	ENSPREP00000031991	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	0.902
LOC103469404	LOC103482184	ENSPREP00000014791	ENSPREP00000005299	Signal transducer and activator of transcription.	Signal transducer and activator of transcription.	0.900
LOC103473964	LOC103460557	ENSPREP00000031991	ENSPREP00000004169	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	0.902
LOC103482184	LOC103469404	ENSPREP00000005299	ENSPREP00000014791	Signal transducer and activator of transcription.	Signal transducer and activator of transcription.	0.900
traf3ip2	ENSPREP00000026492	ENSPREP00000030465	ENSPREP00000026492	SEFIR domain-containing protein.	SEFIR domain-containing protein.	0.900