(28 nodes) Motor neuron axon guidance network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103473450	Ring finger protein 165a. (346 aa)
	LOC103458615	NK2 homeobox 2a. (335 aa)
	LOC103464810	Notum pectinacetylesterase 2. (498 aa)
	cdk5	Cyclin-dependent kinase 5. (262 aa)
	LOC103460162	Chondrolectin. (300 aa)
	rest	RE1-silencing transcription factor. (902 aa)
	ENSPREP00000017507	ANK_REP_REGION domain-containing protein. (191 aa)
	LOC103480490	Netrin 5. (868 aa)
	ENSPREP00000018776	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (824 aa)
	sema3a	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ab; Belongs to the semaphorin family. (799 aa)
	e2f7	E2F transcription factor 7. (798 aa)
	LOC103470112	Ring finger protein 165b. (349 aa)
	LOC103468394	Netrin 1b. (600 aa)
	lhx1	LIM homeobox 1a. (374 aa)
	NTN1	Netrin 1. (606 aa)
	chst11	Carbohydrate sulfotransferase. (352 aa)
	LOC103481112	Netrin 2. (618 aa)
	e2f8	E2F transcription factor 8. (911 aa)
	LOC103465510	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fb; Belongs to the semaphorin family. (699 aa)
	ppp1r12a	Protein phosphatase 1 regulatory subunit. (1113 aa)
	tmem41b	Transmembrane protein 41B. (269 aa)
	LOC103471173	Uncharacterized protein. (191 aa)
	ENSPREP00000010679	Ras homolog gene family, member Gd. (101 aa)
	LOC103470482	Survival of motor neuron 1, telomeric. (308 aa)
	CDH2	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (865 aa)
	sema3f	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fa; Belongs to the semaphorin family. (790 aa)
	LOC103459228	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Aa; Belongs to the semaphorin family. (856 aa)
	RHOG	Ras homolog family member G. (113 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000010679	LOC103471173	ENSPREP00000010679	ENSPREP00000010689	Ras homolog gene family, member Gd.	Uncharacterized protein.	0.902
ENSPREP00000010679	RHOG	ENSPREP00000010679	ENSPREP00000001999	Ras homolog gene family, member Gd.	Ras homolog family member G.	0.901
LOC103459228	cdk5	ENSPREP00000003427	ENSPREP00000011776	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Aa; Belongs to the semaphorin family.	Cyclin-dependent kinase 5.	0.583
LOC103460162	tmem41b	ENSPREP00000015608	ENSPREP00000034090	Chondrolectin.	Transmembrane protein 41B.	0.522
LOC103471173	ENSPREP00000010679	ENSPREP00000010689	ENSPREP00000010679	Uncharacterized protein.	Ras homolog gene family, member Gd.	0.902
LOC103471173	RHOG	ENSPREP00000010689	ENSPREP00000001999	Uncharacterized protein.	Ras homolog family member G.	0.902
RHOG	ENSPREP00000010679	ENSPREP00000001999	ENSPREP00000010679	Ras homolog family member G.	Ras homolog gene family, member Gd.	0.901
RHOG	LOC103471173	ENSPREP00000001999	ENSPREP00000010689	Ras homolog family member G.	Uncharacterized protein.	0.902
cdk5	LOC103459228	ENSPREP00000011776	ENSPREP00000003427	Cyclin-dependent kinase 5.	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Aa; Belongs to the semaphorin family.	0.583
cdk5	sema3a	ENSPREP00000011776	ENSPREP00000020694	Cyclin-dependent kinase 5.	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ab; Belongs to the semaphorin family.	0.583
e2f7	e2f8	ENSPREP00000020702	ENSPREP00000028647	E2F transcription factor 7.	E2F transcription factor 8.	0.646
e2f8	e2f7	ENSPREP00000028647	ENSPREP00000020702	E2F transcription factor 8.	E2F transcription factor 7.	0.646
sema3a	cdk5	ENSPREP00000020694	ENSPREP00000011776	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ab; Belongs to the semaphorin family.	Cyclin-dependent kinase 5.	0.583
tmem41b	LOC103460162	ENSPREP00000034090	ENSPREP00000015608	Transmembrane protein 41B.	Chondrolectin.	0.522