STRINGSTRING
LOC103471931 LOC103471931 sgpl1 sgpl1 LOC103472946 LOC103472946 HSD17B7 HSD17B7 LOC103463731 LOC103463731 LOC103477241 LOC103477241 hsd17b4 hsd17b4 plekha1 plekha1 srd5a1 srd5a1 hsd17b10 hsd17b10
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC1034719313-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (251 aa)
sgpl1Sphingosine-1-phosphate lyase 1. (565 aa)
LOC103472946Hydroxysteroid (17-beta) dehydrogenase 8. (204 aa)
HSD17B7Hydroxysteroid 17-beta dehydrogenase 7. (319 aa)
LOC103463731Hydroxysteroid (17-beta) dehydrogenase 7. (343 aa)
LOC1034772413-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (252 aa)
hsd17b4Hydroxysteroid (17-beta) dehydrogenase 4. (737 aa)
plekha1Pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1b. (333 aa)
srd5a13-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (265 aa)
hsd17b10Hydroxysteroid (17-beta) dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (260 aa)
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.