(24 nodes) poly(U) RNA binding network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	pabpc4	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (626 aa)
	LOC103475888	Musashi RNA-binding protein 2a. (407 aa)
	dis3l2	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily. (1060 aa)
	PNPT1	Polyribonucleotide nucleotidyltransferase 1. (728 aa)
	fmr1	Fragile X mental retardation 1. (273 aa)
	ssb	Small RNA binding exonuclease protection factor La. (382 aa)
	LOC103467593	AXH domain-containing protein. (675 aa)
	RBMS1	RNA binding motif single stranded interacting protein 1. (393 aa)
	atxn1	Ataxin 1a. (795 aa)
	LOC103472449	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (634 aa)
	dazap1	DAZ associated protein 1. (387 aa)
	rbms3	RNA binding motif, single stranded interacting protein. (420 aa)
	LOC103461055	Fragile X mental retardation 1. (400 aa)
	mcrs1	Microspherule protein 1. (474 aa)
	LOC103461084	RRM domain-containing protein. (202 aa)
	LOC103465343	RNA binding motif, single stranded interacting protein 2a. (332 aa)
	ENSPREP00000022545	PABC domain-containing protein. (143 aa)
	LOC103467939	Poly(A) binding protein, cytoplasmic 1-like. (412 aa)
	LOC103472662	RNA binding motif single stranded interacting protein 3. (531 aa)
	ENSPREP00000029931	Zgc:110796. (116 aa)
	LOC103478620	Ataxin 1b. (825 aa)
	pabpc1	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (639 aa)
	LOC103467927	RNA binding motif, single stranded interacting protein 2b. (413 aa)
	LOC103464978	Uncharacterized protein. (329 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC103461055	fmr1	ENSPREP00000020915	ENSPREP00000004643	Fragile X mental retardation 1.	Fragile X mental retardation 1.	0.932
LOC103472449	pabpc1	ENSPREP00000016193	ENSPREP00000030335	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.	0.900
LOC103472449	pabpc4	ENSPREP00000016193	ENSPREP00000002187	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.	0.901
PNPT1	dis3l2	ENSPREP00000004419	ENSPREP00000003433	Polyribonucleotide nucleotidyltransferase 1.	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily.	0.616
dis3l2	PNPT1	ENSPREP00000003433	ENSPREP00000004419	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily.	Polyribonucleotide nucleotidyltransferase 1.	0.616
fmr1	LOC103461055	ENSPREP00000004643	ENSPREP00000020915	Fragile X mental retardation 1.	Fragile X mental retardation 1.	0.932
pabpc1	LOC103472449	ENSPREP00000030335	ENSPREP00000016193	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.	0.900
pabpc1	pabpc4	ENSPREP00000030335	ENSPREP00000002187	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.	0.901
pabpc4	LOC103472449	ENSPREP00000002187	ENSPREP00000016193	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.	0.901
pabpc4	pabpc1	ENSPREP00000002187	ENSPREP00000030335	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.	0.901