(30 nodes) Apoptotic mitochondrial changes network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103462295	Zgc:153993. (263 aa)
	LOC103473973	BCL2 interacting protein 3 like b. (205 aa)
	bad	BCL2 associated agonist of cell death b. (166 aa)
	hspd1	Heat shock 60 protein 1; Belongs to the chaperonin (HSP60) family. (575 aa)
	LOC103478774	Gamma-glutamylcyclotransferase b. (235 aa)
	rhot2	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (623 aa)
	atg3	Autophagy-related protein 3. (315 aa)
	LOC103476353	Uncharacterized protein. (452 aa)
	LOC103468085	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (660 aa)
	jtb	Jumping translocation breakpoint. (150 aa)
	ENSPREP00000021691	Uncharacterized protein. (123 aa)
	gclm	Glutamate-cysteine ligase, modifier subunit. (281 aa)
	aifm2	Apoptosis inducing factor mitochondria associated 2. (360 aa)
	bnip3	BCL2 interacting protein 3. (178 aa)
	LOC103475208	NADH:ubiquinone oxidoreductase core subunit S1; Belongs to the complex I 75 kDa subunit family. (770 aa)
	LOC103459482	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (661 aa)
	BAX	BCL2 associated X, apoptosis regulator. (191 aa)
	LOC103468663	Uncharacterized protein. (200 aa)
	DNM1L	Dynamin 1-like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (731 aa)
	LOC103470563	BCL2 interacting protein 3 like a. (238 aa)
	ENSPREP00000011081	Nuclear apoptosis inducing factor 1. (324 aa)
	LOC103472371	Gamma-glutamylcyclotransferase a. (161 aa)
	LOC103470511	Si:dkey-32e23.4; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (673 aa)
	NDUFS1	NADH:ubiquinone oxidoreductase core subunit S1. (677 aa)
	cfap70	Uncharacterized protein. (1083 aa)
	bcl2	BCL2 apoptosis regulator b. (230 aa)
	LOC103473458	Zgc:73226. (215 aa)
	Bcl2l11	Uncharacterized protein. (202 aa)
	LOC103469295	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (623 aa)
	vps35	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (798 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BAX	Bcl2l11	ENSPREP00000013021	ENSPREP00000002893	BCL2 associated X, apoptosis regulator.	Uncharacterized protein.	0.990
BAX	LOC103462295	ENSPREP00000013021	ENSPREP00000002464	BCL2 associated X, apoptosis regulator.	Zgc:153993.	0.988
BAX	LOC103468663	ENSPREP00000013021	ENSPREP00000012995	BCL2 associated X, apoptosis regulator.	Uncharacterized protein.	0.903
BAX	bad	ENSPREP00000013021	ENSPREP00000030076	BCL2 associated X, apoptosis regulator.	BCL2 associated agonist of cell death b.	0.739
BAX	bcl2	ENSPREP00000013021	ENSPREP00000006116	BCL2 associated X, apoptosis regulator.	BCL2 apoptosis regulator b.	0.995
Bcl2l11	BAX	ENSPREP00000002893	ENSPREP00000013021	Uncharacterized protein.	BCL2 associated X, apoptosis regulator.	0.990
Bcl2l11	ENSPREP00000021691	ENSPREP00000002893	ENSPREP00000021691	Uncharacterized protein.	Uncharacterized protein.	0.932
Bcl2l11	LOC103462295	ENSPREP00000002893	ENSPREP00000002464	Uncharacterized protein.	Zgc:153993.	0.993
Bcl2l11	LOC103468663	ENSPREP00000002893	ENSPREP00000012995	Uncharacterized protein.	Uncharacterized protein.	0.992
Bcl2l11	bad	ENSPREP00000002893	ENSPREP00000030076	Uncharacterized protein.	BCL2 associated agonist of cell death b.	0.751
Bcl2l11	bcl2	ENSPREP00000002893	ENSPREP00000006116	Uncharacterized protein.	BCL2 apoptosis regulator b.	0.997
DNM1L	LOC103470511	ENSPREP00000012725	ENSPREP00000009811	Dynamin 1-like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Si:dkey-32e23.4; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.901
ENSPREP00000021691	Bcl2l11	ENSPREP00000021691	ENSPREP00000002893	Uncharacterized protein.	Uncharacterized protein.	0.932
ENSPREP00000021691	LOC103462295	ENSPREP00000021691	ENSPREP00000002464	Uncharacterized protein.	Zgc:153993.	0.678
ENSPREP00000021691	bad	ENSPREP00000021691	ENSPREP00000030076	Uncharacterized protein.	BCL2 associated agonist of cell death b.	0.779
ENSPREP00000021691	bcl2	ENSPREP00000021691	ENSPREP00000006116	Uncharacterized protein.	BCL2 apoptosis regulator b.	0.678
LOC103462295	BAX	ENSPREP00000002464	ENSPREP00000013021	Zgc:153993.	BCL2 associated X, apoptosis regulator.	0.988
LOC103462295	Bcl2l11	ENSPREP00000002464	ENSPREP00000002893	Zgc:153993.	Uncharacterized protein.	0.993
LOC103462295	ENSPREP00000021691	ENSPREP00000002464	ENSPREP00000021691	Zgc:153993.	Uncharacterized protein.	0.678
LOC103462295	LOC103468663	ENSPREP00000002464	ENSPREP00000012995	Zgc:153993.	Uncharacterized protein.	0.968