STRINGSTRING
aass aass qdpr qdpr abat abat enosf1 enosf1 LOC103459528 LOC103459528 LOC103476059 LOC103476059 SDS SDS gldc gldc etfa etfa sardh sardh shmt2 shmt2 mccc2 mccc2 LOC103463414 LOC103463414 LOC103463413 LOC103463413 arg2 arg2 LOC103459060 LOC103459060 asrgl1 asrgl1 LOC103479659 LOC103479659 tdo2 tdo2 otc otc gstz1 gstz1 aldh6a1 aldh6a1 haao haao LOC103481118 LOC103481118 ENSPREP00000022258 ENSPREP00000022258 pipox pipox got2 got2 aldh5a1 aldh5a1 afmid afmid tat tat hibch hibch gad2 gad2 adhfe1 adhfe1 LOC103461842 LOC103461842 ENSPREP00000001718 ENSPREP00000001718 LOC103478572 LOC103478572 hmgcl hmgcl SHMT2 SHMT2 LOC103472916 LOC103472916 LOC103458637 LOC103458637 kmo kmo aadat aadat amt amt hal hal ENSPREP00000006862 ENSPREP00000006862 slc25a44 slc25a44 nos1 nos1 LOC103469886 LOC103469886 dbt dbt LOC103460681 LOC103460681 LOC103480937 LOC103480937 LOC103480925 LOC103480925 LOC103482433 LOC103482433 hgd hgd kyat3 kyat3 mtrr mtrr cdo1 cdo1 LOC103473756 LOC103473756 LOC103474492 LOC103474492 LOC103465957 LOC103465957 LOC103476765 LOC103476765 acad8 acad8 aldh8a1 aldh8a1 LOC103477344 LOC103477344 LOC103470603 LOC103470603 gcsh gcsh prodh2 prodh2 LOC103463128 LOC103463128 amdhd1 amdhd1 LOC103477017 LOC103477017 fah fah hmgcll1 hmgcll1 dao dao kynu kynu kyat1 kyat1 LOC103472186 LOC103472186 LOC103457187 LOC103457187 aldh4a1 aldh4a1 GOT1 GOT1 DDAH1 DDAH1 hsd17b10 hsd17b10 got1 got1 DLST DLST LOC103472118 LOC103472118 LOC103472117 LOC103472117 LOC103457629 LOC103457629 LOC103468491 LOC103468491 shmt1 shmt1 agxt2 agxt2 LOC103479856 LOC103479856 ddo ddo ivd ivd acmsd acmsd bckdha bckdha LOC103481893 LOC103481893 LOC103461196 LOC103461196 LOC103474367 LOC103474367 LOC103464825 LOC103464825 LOC103457893 LOC103457893 bckdk bckdk bckdhb bckdhb ENSPREP00000022276 ENSPREP00000022276 LOC103480938 LOC103480938 gls2 gls2 LOC103470503 LOC103470503 blmh blmh ENSPREP00000010030 ENSPREP00000010030 pah pah oat oat
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
aassAminoadipate-semialdehyde synthase. (931 aa)
qdprQuinoid dihydropteridine reductase a. (313 aa)
abat4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (500 aa)
enosf1Enolase superfamily member 1. (433 aa)
LOC103459528Si:ch73-263o4.3. (313 aa)
LOC1034760594-hydroxyphenylpyruvate dioxygenase. (367 aa)
SDSSerine dehydratase. (346 aa)
gldcGlycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (1043 aa)
etfaElectron transfer flavoprotein subunit alpha. (347 aa)
sardhSarcosine dehydrogenase. (916 aa)
shmt2Serine hydroxymethyltransferase 2 (mitochondrial). (515 aa)
mccc2Methylcrotonoyl-CoA carboxylase 2 (beta). (564 aa)
LOC103463414Aminotran_1_2 domain-containing protein. (460 aa)
LOC103463413Aminotran_1_2 domain-containing protein. (483 aa)
arg2Arginase. (346 aa)
LOC103459060Dihydrolipoamide S-succinyltransferase. (433 aa)
asrgl1Asparaginase like 1. (346 aa)
LOC103479659Aminotran_1_2 domain-containing protein. (538 aa)
tdo2Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (403 aa)
otcOrnithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (319 aa)
gstz1Glutathione S-transferase zeta 1; Belongs to the GST superfamily. (273 aa)
aldh6a1Aldehyde dehydrogenase 6 family member A1. (526 aa)
haao3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. (287 aa)
LOC103481118Formimidoyltransferase cyclodeaminase. (539 aa)
ENSPREP00000022258Glycine C-acetyltransferase. (345 aa)
pipoxPipecolic acid oxidase. (388 aa)
got2Aspartate aminotransferase. (393 aa)
aldh5a1Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (513 aa)
afmidKynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. (292 aa)
tatTyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. (449 aa)
hibch3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. (382 aa)
gad2Glutamate decarboxylase 2. (585 aa)
adhfe1Alcohol dehydrogenase iron containing 1. (526 aa)
LOC103461842EF-hand_14 domain-containing protein. (563 aa)
ENSPREP00000001718Uncharacterized protein. (156 aa)
LOC1034785723-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (336 aa)
hmgcl3-hydroxy-3-methylglutaryl-CoA lyase. (298 aa)
SHMT2Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (530 aa)
LOC103472916Dimethylarginine dimethylaminohydrolase 2. (265 aa)
LOC103458637L-threonine dehydrogenase 2. (308 aa)
kmoKynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. (480 aa)
aadatAminoadipate aminotransferase. (437 aa)
amtAminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. (415 aa)
halHistidine ammonia-lyase; Belongs to the PAL/histidase family. (654 aa)
ENSPREP00000006862Uncharacterized protein. (144 aa)
slc25a44Solute carrier family 25 member 44b; Belongs to the mitochondrial carrier (TC 2.A.29) family. (315 aa)
nos1Nitric oxide synthase 1 (neuronal). (1436 aa)
LOC103469886Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (624 aa)
dbtDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (492 aa)
LOC103460681Serine dehydratase-like. (313 aa)
LOC103480937Amine oxidase. (541 aa)
LOC103480925Amine oxidase. (545 aa)
LOC103482433Si:ch211-217a12.1. (991 aa)
hgdHomogentisate 1,2-dioxygenase. (443 aa)
kyat3Kynurenine aminotransferase 3. (459 aa)
mtrr5-methyltetrahydrofolate-homocysteine methyltransferase reductase. (713 aa)
cdo1Cysteine dioxygenase. (202 aa)
LOC103473756Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (625 aa)
LOC103474492Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (582 aa)
LOC103465957Solute carrier family 25 member 44a; Belongs to the mitochondrial carrier (TC 2.A.29) family. (317 aa)
LOC103476765Uncharacterized protein. (409 aa)
acad8Acyl-CoA dehydrogenase family, member 8. (419 aa)
aldh8a1Aldehyde dehydrogenase 8 family, member A1; Belongs to the aldehyde dehydrogenase family. (490 aa)
LOC103477344PALP domain-containing protein. (529 aa)
LOC1034706034-hydroxyphenylpyruvate dioxygenase b. (559 aa)
gcshGlycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (174 aa)
prodh2Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (472 aa)
LOC103463128Si:ch211-198n5.11. (534 aa)
amdhd1Amidohydrolase domain containing 1. (432 aa)
LOC103477017Si:dkey-103j14.5. (311 aa)
fahFumarylacetoacetase. (333 aa)
hmgcll13-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1. (336 aa)
daoD-amino-acid oxidase, tandem duplicate 2. (316 aa)
kynuKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (463 aa)
kyat1Kynurenine aminotransferase 1. (459 aa)
LOC1034721863-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (326 aa)
LOC103457187Glutaminase a. (617 aa)
aldh4a1Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. (592 aa)
GOT1Aspartate aminotransferase. (463 aa)
DDAH1Dimethylarginine dimethylaminohydrolase 1. (138 aa)
hsd17b10Hydroxysteroid (17-beta) dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (260 aa)
got1Aspartate aminotransferase. (398 aa)
DLSTDihydrolipoamide S-succinyltransferase. (436 aa)
LOC103472118Glutathione S-transferase rho; Belongs to the GST superfamily. (215 aa)
LOC103472117Uncharacterized protein; Belongs to the GST superfamily. (226 aa)
LOC103457629L-threonine dehydrogenase. (374 aa)
LOC103468491Si:ch211-256m1.8. (1577 aa)
shmt1Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (442 aa)
agxt2Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (517 aa)
LOC103479856Glutamic pyruvate transaminase (alanine aminotransferase) 2, like. (542 aa)
ddoZgc:172341. (338 aa)
ivdIsovaleryl-CoA dehydrogenase. (417 aa)
acmsd2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily. (336 aa)
bckdha2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (447 aa)
LOC103481893Arginase. (371 aa)
LOC103461196Amine oxidase. (512 aa)
LOC103474367Amine oxidase. (551 aa)
LOC103464825Glutaminase 2b (liver, mitochondrial). (514 aa)
LOC103457893Aldedh domain-containing protein. (493 aa)
bckdkProtein-serine/threonine kinase. (429 aa)
bckdhbBranched chain keto acid dehydrogenase E1 subunit beta. (387 aa)
ENSPREP00000022276Uncharacterized protein. (107 aa)
LOC103480938Amino_oxidase domain-containing protein. (564 aa)
gls2Glutaminase 2a (liver, mitochondrial). (600 aa)
LOC103470503Indoleamine 2,3-dioxygenase 1. (422 aa)
blmhBleomycin hydrolase; Belongs to the peptidase C1 family. (484 aa)
ENSPREP00000010030Electron transfer flavoprotein subunit beta. (243 aa)
pahPhenylalanine hydroxylase. (459 aa)
oatOrnithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (478 aa)
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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