(39 nodes) Serine family amino acid metabolic process network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103474492	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (582 aa)
	LOC103477896	Sulfurtransferase. (292 aa)
	SHMT2	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (530 aa)
	LOC103458637	L-threonine dehydrogenase 2. (308 aa)
	phgdh	D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (527 aa)
	amt	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. (415 aa)
	ENSPREP00000006862	Uncharacterized protein. (144 aa)
	LOC103466942	Selenophosphate synthetase 2. (334 aa)
	LOC103460681	Serine dehydratase-like. (313 aa)
	cth	Cystathionase (cystathionine gamma-lyase), like. (441 aa)
	LOC103461416	Serine--pyruvate aminotransferase. (360 aa)
	gcsh	Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (174 aa)
	THNSL1	Threonine synthase like 1. (723 aa)
	LOC103459803	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (587 aa)
	gclc	Glutamate-cysteine ligase, catalytic subunit. (630 aa)
	dao	D-amino-acid oxidase, tandem duplicate 2. (316 aa)
	psph	Phosphoserine phosphatase. (244 aa)
	LOC103459081	Acyl-CoA thioesterase 16. (438 aa)
	LOC103478854	Zgc:162816. (370 aa)
	LOC103457629	L-threonine dehydrogenase. (374 aa)
	LOC103468490	Thiosulfate sulfurtransferase. (294 aa)
	LOC103468489	Sulfurtransferase. (297 aa)
	LOC103468488	Sulfurtransferase. (294 aa)
	shmt1	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (442 aa)
	agxt2	Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (517 aa)
	scly	Selenocysteine lyase. (433 aa)
	sephs1	Selenophosphate synthetase 1. (392 aa)
	LOC103463960	Serine--pyruvate aminotransferase. (434 aa)
	gclm	Glutamate-cysteine ligase, modifier subunit. (281 aa)
	ENSPREP00000019658	Uncharacterized protein. (441 aa)
	cdo1	Cysteine dioxygenase. (202 aa)
	dhfr	Dihydrofolate reductase. (187 aa)
	LOC103477344	PALP domain-containing protein. (529 aa)
	psat1	Phosphoserine aminotransferase. (369 aa)
	shmt2	Serine hydroxymethyltransferase 2 (mitochondrial). (515 aa)
	gldc	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (1043 aa)
	SDS	Serine dehydratase. (346 aa)
	LOC103459528	Si:ch73-263o4.3. (313 aa)
	thnsl2	Threonine synthase-like 2. (401 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000006862	LOC103461416	ENSPREP00000006862	ENSPREP00000009299	Uncharacterized protein.	Serine--pyruvate aminotransferase.	0.505
ENSPREP00000006862	LOC103463960	ENSPREP00000006862	ENSPREP00000021768	Uncharacterized protein.	Serine--pyruvate aminotransferase.	0.505
ENSPREP00000006862	SHMT2	ENSPREP00000006862	ENSPREP00000002198	Uncharacterized protein.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.833
ENSPREP00000006862	amt	ENSPREP00000006862	ENSPREP00000005551	Uncharacterized protein.	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	0.978
ENSPREP00000006862	dao	ENSPREP00000006862	ENSPREP00000032680	Uncharacterized protein.	D-amino-acid oxidase, tandem duplicate 2.	0.505
ENSPREP00000006862	dhfr	ENSPREP00000006862	ENSPREP00000017926	Uncharacterized protein.	Dihydrofolate reductase.	0.774
ENSPREP00000006862	gldc	ENSPREP00000006862	ENSPREP00000012159	Uncharacterized protein.	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine.	0.993
ENSPREP00000006862	phgdh	ENSPREP00000006862	ENSPREP00000005247	Uncharacterized protein.	D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.606
ENSPREP00000006862	psat1	ENSPREP00000006862	ENSPREP00000013365	Uncharacterized protein.	Phosphoserine aminotransferase.	0.588
ENSPREP00000006862	shmt1	ENSPREP00000006862	ENSPREP00000026863	Uncharacterized protein.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.833
ENSPREP00000006862	shmt2	ENSPREP00000006862	ENSPREP00000012687	Uncharacterized protein.	Serine hydroxymethyltransferase 2 (mitochondrial).	0.833
LOC103457629	LOC103458637	ENSPREP00000028085	ENSPREP00000003651	L-threonine dehydrogenase.	L-threonine dehydrogenase 2.	0.901
LOC103457629	LOC103460681	ENSPREP00000028085	ENSPREP00000008434	L-threonine dehydrogenase.	Serine dehydratase-like.	0.916
LOC103457629	LOC103477344	ENSPREP00000028085	ENSPREP00000016103	L-threonine dehydrogenase.	PALP domain-containing protein.	0.920
LOC103457629	SDS	ENSPREP00000028085	ENSPREP00000012057	L-threonine dehydrogenase.	Serine dehydratase.	0.916
LOC103458637	LOC103457629	ENSPREP00000003651	ENSPREP00000028085	L-threonine dehydrogenase 2.	L-threonine dehydrogenase.	0.901
LOC103458637	LOC103460681	ENSPREP00000003651	ENSPREP00000008434	L-threonine dehydrogenase 2.	Serine dehydratase-like.	0.916
LOC103458637	LOC103477344	ENSPREP00000003651	ENSPREP00000016103	L-threonine dehydrogenase 2.	PALP domain-containing protein.	0.920
LOC103458637	SDS	ENSPREP00000003651	ENSPREP00000012057	L-threonine dehydrogenase 2.	Serine dehydratase.	0.916
LOC103459528	LOC103459803	ENSPREP00000011705	ENSPREP00000033502	Si:ch73-263o4.3.	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.	0.545