(64 nodes) Protein secretion network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	golph3	Si:dkey-27b3.2. (294 aa)
	porcn	Porcupine O-acyltransferase; Belongs to the membrane-bound acyltransferase family. (425 aa)
	pclo	Piccolo presynaptic cytomatrix protein a. (3491 aa)
	ADCYAP1	Adenylate cyclase activating polypeptide 1a. (202 aa)
	vip	Vasoactive intestinal peptide. (184 aa)
	LOC103459074	Endothelin receptor type Bb; Belongs to the G-protein coupled receptor 1 family. (424 aa)
	LOC103478941	Endothelin receptor Ba; Belongs to the G-protein coupled receptor 1 family. (467 aa)
	LOC103461426	Uncharacterized protein. (115 aa)
	park7	Parkinson protein 7. (189 aa)
	LOC103463266	RAB3B, member RAS oncogene family. (217 aa)
	LOC103458407	Rap guanine nucleotide exchange factor (GEF) 4. (917 aa)
	LOC103481534	Synuclein, gamma b (breast cancer-specific protein 1); Belongs to the synuclein family. (234 aa)
	mttp	Microsomal triglyceride transfer protein. (890 aa)
	ccdc186	Si:ch211-225b10.4. (996 aa)
	stxbp3	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (592 aa)
	trappc11	Trafficking protein particle complex 11. (1123 aa)
	c1qtnf5	C1q and TNF related 5. (250 aa)
	LOC103475800	Sorting nexin 19a. (998 aa)
	tmem167a	Protein kish; Involved in the early part of the secretory pathway. Belongs to the KISH family. (72 aa)
	LOC103482185	Caveolae associated protein 1b. (397 aa)
	LOC103470946	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (423 aa)
	bloc1s3	Biogenesis of lysosome-related organelles complex 1 subunit 3; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO). Belongs to the BLOC1S3 family. (195 aa)
	hnf1a	HNF1 homeobox a. (550 aa)
	hps1	HPS1 biogenesis of lysosomal organelles complex 3 subunit 1. (657 aa)
	LOC103458514	RAB15, member RAS oncogene family. (210 aa)
	tango6	Transport and golgi organization 6 homolog (Drosophila). (1037 aa)
	tango2	Transport and golgi organization 2 homolog (Drosophila). (275 aa)
	preb	Prolactin regulatory element binding. (428 aa)
	nagpa	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase. (594 aa)
	rab3c	RAB3C, member RAS oncogene family. (219 aa)
	svbp	Small vasohibin binding protein. (66 aa)
	ENSPREP00000004325	Golgi apparatus membrane protein TVP23 homolog. (191 aa)
	rab13	RAB13, member RAS oncogene family. (216 aa)
	rab12	RAB12, member RAS oncogene family. (244 aa)
	LOC103469641	Golgi phosphoprotein 3. (245 aa)
	rab10	RAB10, member RAS oncogene family. (225 aa)
	snx19	Sorting nexin 19b. (977 aa)
	plek	Pleckstrin. (351 aa)
	ENSPREP00000021170	Uncharacterized protein. (167 aa)
	ENSPREP00000020827	Uncharacterized protein. (1109 aa)
	GPR119	G protein-coupled receptor 119; Belongs to the G-protein coupled receptor 1 family. (416 aa)
	LOC103468508	Uncharacterized protein. (221 aa)
	rab3d	RAB3D, member RAS oncogene family, b. (222 aa)
	sel1l	SEL1L adaptor subunit of ERAD E3 ubiquitin ligase. (825 aa)
	rab8a	RAB8A, member RAS oncogene family. (206 aa)
	sncg	Gamma-synuclein; Belongs to the synuclein family. (122 aa)
	LOC103479775	RAB8A, member RAS oncogene family. (234 aa)
	LOC103463328	RAB3A, member RAS oncogene family, b. (219 aa)
	LOC103457353	RAB15, member RAS oncogene family. (213 aa)
	m6pr	Mannose-6-phosphate receptor (cation dependent). (281 aa)
	LOC103479175	RAB3A, member RAS oncogene family, b. (290 aa)
	LOC103469402	Caveolae associated protein 1a. (393 aa)
	Hnf1b	HNF1 homeobox Ba. (422 aa)
	rab8b	Multiple EGF-like-domains 8. (207 aa)
	LOC103460086	Uncharacterized protein. (206 aa)
	bloc1s6	Biogenesis of lysosome-related organelles complex 1 subunit 6; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particular [...] (169 aa)
	LOC103466972	Uncharacterized protein; Belongs to the membrane-bound acyltransferase family. (481 aa)
	mia3	Uncharacterized protein. (801 aa)
	ENSPREP00000012170	SH3 domain-containing protein. (149 aa)
	cplx3	Complexin 3b. (156 aa)
	LOC103481595	Golgi apparatus membrane protein TVP23 homolog. (206 aa)
	wls	Wnt ligand secretion mediator. (448 aa)
	ENSPREP00000011366	MIA SH3 domain ER export factor 2. (539 aa)
	Ctage5	SH3 domain-containing protein. (1647 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCYAP1	LOC103461426	ENSPREP00000011176	ENSPREP00000009561	Adenylate cyclase activating polypeptide 1a.	Uncharacterized protein.	0.902
Ctage5	ENSPREP00000011366	ENSPREP00000011308	ENSPREP00000011366	SH3 domain-containing protein.	MIA SH3 domain ER export factor 2.	0.700
Ctage5	preb	ENSPREP00000011308	ENSPREP00000027267	SH3 domain-containing protein.	Prolactin regulatory element binding.	0.798
ENSPREP00000011366	Ctage5	ENSPREP00000011366	ENSPREP00000011308	MIA SH3 domain ER export factor 2.	SH3 domain-containing protein.	0.700
ENSPREP00000011366	preb	ENSPREP00000011366	ENSPREP00000027267	MIA SH3 domain ER export factor 2.	Prolactin regulatory element binding.	0.763
ENSPREP00000012170	mia3	ENSPREP00000012170	ENSPREP00000012201	SH3 domain-containing protein.	Uncharacterized protein.	0.898
ENSPREP00000012170	preb	ENSPREP00000012170	ENSPREP00000027267	SH3 domain-containing protein.	Prolactin regulatory element binding.	0.763
ENSPREP00000020827	LOC103458407	ENSPREP00000020827	ENSPREP00000007320	Uncharacterized protein.	Rap guanine nucleotide exchange factor (GEF) 4.	0.427
LOC103458407	ENSPREP00000020827	ENSPREP00000007320	ENSPREP00000020827	Rap guanine nucleotide exchange factor (GEF) 4.	Uncharacterized protein.	0.427
LOC103458407	pclo	ENSPREP00000007320	ENSPREP00000003339	Rap guanine nucleotide exchange factor (GEF) 4.	Piccolo presynaptic cytomatrix protein a.	0.427
LOC103459074	LOC103470946	ENSPREP00000002951	ENSPREP00000032490	Endothelin receptor type Bb; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.902
LOC103459074	LOC103478941	ENSPREP00000002951	ENSPREP00000002847	Endothelin receptor type Bb; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor Ba; Belongs to the G-protein coupled receptor 1 family.	0.902
LOC103461426	ADCYAP1	ENSPREP00000009561	ENSPREP00000011176	Uncharacterized protein.	Adenylate cyclase activating polypeptide 1a.	0.902
LOC103463266	stxbp3	ENSPREP00000008163	ENSPREP00000033356	RAB3B, member RAS oncogene family.	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.	0.495
LOC103463328	rab8b	ENSPREP00000016866	ENSPREP00000013376	RAB3A, member RAS oncogene family, b.	Multiple EGF-like-domains 8.	0.417
LOC103463328	stxbp3	ENSPREP00000016866	ENSPREP00000033356	RAB3A, member RAS oncogene family, b.	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.	0.495
LOC103466972	wls	ENSPREP00000012214	ENSPREP00000012076	Uncharacterized protein; Belongs to the membrane-bound acyltransferase family.	Wnt ligand secretion mediator.	0.502
LOC103468508	stxbp3	ENSPREP00000019661	ENSPREP00000033356	Uncharacterized protein.	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.	0.495
LOC103470946	LOC103459074	ENSPREP00000032490	ENSPREP00000002951	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type Bb; Belongs to the G-protein coupled receptor 1 family.	0.902
LOC103470946	LOC103478941	ENSPREP00000032490	ENSPREP00000002847	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor Ba; Belongs to the G-protein coupled receptor 1 family.	0.901