STRINGSTRING
rad9a rad9a LOC103475461 LOC103475461 ercc8 ercc8 uimc1 uimc1 msh2 msh2 cdca7 cdca7 map3k20 map3k20 babam2 babam2 kdm1a kdm1a bcl2 bcl2 Xrcc4 Xrcc4 men1 men1 abcg5 abcg5 cdca7l cdca7l sirt1 sirt1 LOC103467741 LOC103467741 LOC103462295 LOC103462295 rfwd3 rfwd3 rad51 rad51 sfrp2 sfrp2 stk11 stk11 LOC103472103 LOC103472103 LOC103475119 LOC103475119 ENSPREP00000027944 ENSPREP00000027944 LOC103474475 LOC103474475 Brcc3 Brcc3 itgb6 itgb6 zmpste24 zmpste24 LOC103461892 LOC103461892 xrcc6 xrcc6 cop1 cop1 ENSPREP00000007980 ENSPREP00000007980 INIP INIP ENSPREP00000008127 ENSPREP00000008127 ticrr ticrr ENSPREP00000008303 ENSPREP00000008303 brat1 brat1 ENSPREP00000009572 ENSPREP00000009572 lig4 lig4 ENSPREP00000031399 ENSPREP00000031399 ercc6 ercc6 blm blm LOC103468682 LOC103468682 tank tank ENSPREP00000012278 ENSPREP00000012278 rnf8 rnf8 SPIDR SPIDR BAX BAX fancd2 fancd2 xrcc5 xrcc5 ENSPREP00000014560 ENSPREP00000014560 ENSPREP00000015300 ENSPREP00000015300 ercc1 ercc1 LOC103464656 LOC103464656 xrcc2 xrcc2 mfsd11 mfsd11 rhno1 rhno1 brca1 brca1 LOC103464365 LOC103464365 Clg10h5orf45 Clg10h5orf45 atr atr LOC103476762 LOC103476762 bard1 bard1 brca2 brca2 ptprc ptprc abraxas1 abraxas1 ikbip ikbip kars1 kars1 babam1 babam1 ENSPREP00000018722 ENSPREP00000018722 ect2 ect2 LOC103479332 LOC103479332 LOC103473172 LOC103473172 ino80 ino80 smpd1 smpd1 LOC103464822 LOC103464822 ints3 ints3 rad9b rad9b chek2 chek2 topbp1 topbp1 fbxo4 fbxo4 atm atm ENSPREP00000025048 ENSPREP00000025048 dcun1d3 dcun1d3 rad1 rad1 tp53bp1 tp53bp1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rad9aCell cycle checkpoint control protein; Belongs to the rad9 family. (387 aa)
LOC103475461Crystallin, alpha B, a; Belongs to the small heat shock protein (HSP20) family. (164 aa)
ercc8Excision repair cross-complementation group 8. (401 aa)
uimc1Uncharacterized protein. (985 aa)
msh2DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (937 aa)
cdca7Cell division cycle associated 7a. (403 aa)
map3k20Uncharacterized protein. (796 aa)
babam2BRISC and BRCA1 A complex member 2. (386 aa)
kdm1aLysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (855 aa)
bcl2BCL2 apoptosis regulator b. (230 aa)
Xrcc4Uncharacterized protein. (159 aa)
men1Multiple endocrine neoplasia I. (627 aa)
abcg5ATP-binding cassette, sub-family G (WHITE), member 5. (608 aa)
cdca7lCell division cycle associated 7b. (397 aa)
sirt1Sirtuin 1. (677 aa)
LOC103467741DNA (cytosine-5-)-methyltransferase 3 beta, duplicate a; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1451 aa)
LOC103462295Zgc:153993. (263 aa)
rfwd3Ring finger and WD repeat domain 3. (893 aa)
rad51RAD51 recombinase. (219 aa)
sfrp2Secreted frizzled-related protein 2. (295 aa)
stk11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (438 aa)
LOC103472103Ints3 and nabp interacting protein. (103 aa)
LOC103475119Transforming growth factor beta; Belongs to the TGF-beta family. (380 aa)
ENSPREP00000027944Reverse transcriptase domain-containing protein. (1281 aa)
LOC103474475Uncharacterized protein. (342 aa)
Brcc3BRCA1/BRCA2-containing complex, subunit 3. (251 aa)
itgb6Integrin beta; Belongs to the integrin beta chain family. (780 aa)
zmpste24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (471 aa)
LOC103461892Nucleic acid binding protein 1a. (205 aa)
xrcc6X-ray repair complementing defective repair in Chinese hamster cells 6. (655 aa)
cop1COP1 E3 ubiquitin ligase. (661 aa)
ENSPREP00000007980Reverse transcriptase domain-containing protein. (282 aa)
INIPINTS3 and NABP interacting protein. (102 aa)
ENSPREP00000008127Reverse transcriptase domain-containing protein. (1242 aa)
ticrrTreslin_N domain-containing protein. (1692 aa)
ENSPREP00000008303Reverse transcriptase domain-containing protein. (353 aa)
brat1Uncharacterized protein. (864 aa)
ENSPREP00000009572Reverse transcriptase domain-containing protein. (554 aa)
lig4DNA ligase. (908 aa)
ENSPREP00000031399Ring finger protein 168. (425 aa)
ercc6Excision repair cross-complementation group 6. (1402 aa)
blmBLM RecQ like helicase. (1399 aa)
LOC103468682Uncharacterized protein. (455 aa)
tankTRAF family member-associated NFKB activator. (338 aa)
ENSPREP00000012278SWI5 homologous recombination repair protein. (88 aa)
rnf8E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (490 aa)
SPIDRScaffold protein involved in DNA repair. (934 aa)
BAXBCL2 associated X, apoptosis regulator. (191 aa)
fancd2FA complementation group D2. (1432 aa)
xrcc5X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (731 aa)
ENSPREP00000014560Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (483 aa)
ENSPREP00000015300Reverse transcriptase domain-containing protein. (415 aa)
ercc1Excision repair cross-complementation group 1. (358 aa)
LOC103464656Deoxyribonuclease; Belongs to the DNase I family. (308 aa)
xrcc2X-ray repair cross complementing 2. (292 aa)
mfsd11Major facilitator superfamily domain containing 11. (454 aa)
rhno1Si:ch73-352p4.5. (221 aa)
brca1Uncharacterized protein. (1344 aa)
LOC103464365Deoxyribonuclease; Belongs to the DNase I family. (266 aa)
Clg10h5orf45Uncharacterized protein. (78 aa)
atrATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2589 aa)
LOC103476762ALMS_motif domain-containing protein. (417 aa)
bard1BRCA1 associated RING domain 1. (722 aa)
brca2BRCA2 DNA repair associated. (3038 aa)
ptprcProtein tyrosine phosphatase receptor type C. (1230 aa)
abraxas1Abraxas 1, BRCA1 A complex subunit. (349 aa)
ikbipUncharacterized protein. (371 aa)
kars1Lysine--tRNA ligase. (609 aa)
babam1BRISC and BRCA1 A complex member 1. (355 aa)
ENSPREP00000018722Reverse transcriptase domain-containing protein. (253 aa)
ect2Epithelial cell transforming 2. (1097 aa)
LOC103479332Protein kinase domain-containing protein. (674 aa)
LOC103473172X-ray repair complementing defective repair in Chinese hamster cells 4. (340 aa)
ino80INO80 complex ATPase subunit. (1484 aa)
smpd1Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (602 aa)
LOC103464822Deoxyribonuclease 1 like 4, tandem duplicate 2. (372 aa)
ints3Integrator complex subunit 3. (1019 aa)
rad9bRAD9 checkpoint clamp component B. (442 aa)
chek2Checkpoint kinase 2. (510 aa)
topbp1DNA topoisomerase II binding protein 1. (1453 aa)
fbxo4F-box protein 4. (361 aa)
atmNon-specific serine/threonine protein kinase. (3091 aa)
ENSPREP00000025048Deoxyribonuclease; Belongs to the DNase I family. (287 aa)
dcun1d3DCN1-like protein. (326 aa)
rad1RAD1 homolog (S. pombe). (279 aa)
tp53bp1Tumor protein p53 binding protein, 1. (1579 aa)
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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