121 items (Poecilia reticulata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103456761	Apolipoprotein Db; Belongs to the calycin superfamily. Lipocalin family. (182 aa)
	LOC103461979	LIM and senescent cell antigen-like domains 2. (203 aa)
	wdpcp	WD repeat containing planar cell polarity effector. (512 aa)
	ccn1	Cellular communication network factor 1. (536 aa)
	cask	Uncharacterized protein; Belongs to the MAGUK family. (884 aa)
	ENSPREP00000030675	Cas scaffold protein family member 4. (795 aa)
	fzd4	Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (531 aa)
	ENSPREP00000030492	Uncharacterized protein. (515 aa)
	ccdc80	Coiled-coil domain containing 80. (871 aa)
	LOC103476509	Ras and Rab interactor 2. (944 aa)
	LOC103468546	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (220 aa)
	arl2	ADP-ribosylation factor-like 2; Belongs to the small GTPase superfamily. Arf family. (184 aa)
	ENSPREP00000030224	PID domain-containing protein. (124 aa)
	GREM1	Gremlin. (182 aa)
	LOC103481976	Uncharacterized protein. (193 aa)
	ENSPREP00000029693	Uncharacterized protein. (89 aa)
	cspg5	Chondroitin sulfate proteoglycan 5a. (605 aa)
	LOC103481975-2	Uncharacterized protein. (195 aa)
	LOC103481975	Uncharacterized protein. (191 aa)
	ptpra	Receptor-type tyrosine-protein phosphatase. (807 aa)
	EGFLAM	EGF like, fibronectin type III and laminin G domains. (1067 aa)
	LOC103472693	Protein S100; Belongs to the S-100 family. (100 aa)
	LOC103457606	Protein tyrosine kinase 2 beta, b; Belongs to the protein kinase superfamily. Tyr protein kinase family. (994 aa)
	LOC103457775	Elastin microfibril interfacer 1a. (1023 aa)
	LOC103481154	MARVEL domain-containing protein. (288 aa)
	LOC103481123	Uncharacterized protein. (280 aa)
	ENSPREP00000027807	Platelet-derived growth factor beta polypeptide b; Belongs to the PDGF/VEGF growth factor family. (393 aa)
	cib1	Calcium and integrin binding 1 (calmyrin). (195 aa)
	ndnf	Neuron-derived neurotrophic factor. (571 aa)
	LOC103465423	Cell division cycle 42. (191 aa)
	fermt1	Fermitin family member 1. (666 aa)
	EFNA5	Ephrin A5; Belongs to the ephrin family. (224 aa)
	ENSPREP00000023825	SH2 domain-containing protein. (93 aa)
	LOC103467541	Colony stimulating factor 1b (macrophage). (266 aa)
	LOC103460487	Fibronectin 1a. (2502 aa)
	ENSPREP00000022997	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (200 aa)
	bcas3	BCAS3 microtubule associated cell migration factor. (666 aa)
	ilk	Uncharacterized protein. (465 aa)
	nf1	Neurofibromin 1b. (2742 aa)
	LOC103479802	Apolipoprotein Da, duplicate 1; Belongs to the calycin superfamily. Lipocalin family. (186 aa)
	ENSPREP00000019776	C-C motif chemokine. (110 aa)
	LOC103461059	LIM and senescent cell antigen-like domains 2. (438 aa)
	LOC103479263	Eph receptor A4b. (949 aa)
	LOC103474773	Glycoprotein M6Ba. (372 aa)
	LOC103471920	Anterior gradient 2. (159 aa)
	vegfa	Vascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family. (214 aa)
	LOC103477991	Uncharacterized protein. (191 aa)
	LOC103472469	Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1080 aa)
	LOC103475221	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (942 aa)
	LOC103477993	Uncharacterized protein. (134 aa)
	ajap1	Adherens junctions associated protein 1. (397 aa)
	epcam	Epithelial cell adhesion molecule. (309 aa)
	tsta3	Tissue specific transplantation antigen P35B. (328 aa)
	rreb1	Ras responsive element binding protein 1a. (1526 aa)
	ECM2	Extracellular matrix protein 2. (595 aa)
	LOC103476709	Neuron-derived neurotrophic factor, like. (581 aa)
	ptk2	Protein tyrosine kinase 2ab; Belongs to the protein kinase superfamily. Tyr protein kinase family. (878 aa)
	crk	CRK proto-oncogene, adaptor protein. (315 aa)
	LOC103475843	Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family. (950 aa)
	poldip2	Polymerase (DNA-directed), delta interacting protein 2. (377 aa)
	FBLN2	Fibulin 2. (998 aa)
	ENSPREP00000013424	Olfactomedin-like domain-containing protein. (446 aa)
	LOC103459061	Si:ch211-173a9.6. (409 aa)
	LOC103460095	Elastin microfibril interfacer 1b. (1203 aa)
	nedd9	Neural precursor cell expressed, developmentally down-regulated 9. (792 aa)
	LOC103475650	Vitronectin b. (444 aa)
	ILK	Integrin linked kinase. (452 aa)
	ENSPREP00000012400	Uncharacterized protein. (550 aa)
	LOC103480351	Uncharacterized protein. (282 aa)
	c1qbp	Complement component 1, q subcomponent binding protein. (289 aa)
	LOC103474828	Apolipoprotein A-Ib. (263 aa)
	abi3bp	Fibronectin type-III domain-containing protein. (804 aa)
	Limch1	DUF4757 domain-containing protein. (156 aa)
	ENSPREP00000010219	Calponin-homology (CH) domain-containing protein. (125 aa)
	crkl	V-crk avian sarcoma virus CT10 oncogene homolog-like. (310 aa)
	RAC1	Rac family small GTPase 1. (192 aa)
	bcar1	BCAR1 scaffold protein, Cas family member. (944 aa)
	nrp1	Neuropilin; Belongs to the neuropilin family. (903 aa)
	LOC103474014	Ephrin-A5a; Belongs to the ephrin family. (229 aa)
	spry4	Sprouty homolog 4 (Drosophila). (283 aa)
	rsu1	Ras suppressor protein 1. (351 aa)
	acer2	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (275 aa)
	itgb1bp1	Integrin beta 1 binding protein 1. (193 aa)
	nexmif	Neurite extension and migration factor b. (1422 aa)
	rasa1	RAS p21 protein activator (GTPase activating protein) 1a. (1049 aa)
	bcl2	BCL2 apoptosis regulator b. (230 aa)
	CDC42	Cell division cycle 42. (191 aa)
	LOC103478985	Olfactomedin-like domain-containing protein. (500 aa)
	LOC103472278	Chondroitin sulfate proteoglycan 5b. (651 aa)
	tesk1	Si:dkeyp-75h12.2. (677 aa)
	tbcd	Tubulin folding cofactor D. (1231 aa)
	ap1ar	Adaptor related protein complex 1 associated regulatory protein. (291 aa)
	LOC103482188	Rac family small GTPase 3b. (203 aa)
	lrrc45	Leucine rich repeat containing 45. (674 aa)
	LOC103480133	Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; Belongs to the serpin family. (390 aa)
	vcl	Vinculin b. (1100 aa)
	RIN2	Ras and Rab interactor 2. (993 aa)
	spock2	SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2. (444 aa)
	ARHGAP6	Rho GTPase activating protein 6. (507 aa)
	egfl6	EGF-like-domain, multiple 6. (540 aa)
	vwc2	Von Willebrand factor C domain containing 2. (299 aa)
	LOC103474670	EMI domain-containing protein. (435 aa)
	plekha2	Uncharacterized protein. (430 aa)
	LOC103472837	Uncharacterized protein. (196 aa)
	LOC103479524	Si:dkeyp-66d1.7. (293 aa)
	myoc	Myocilin. (482 aa)
	LOC103469310	Uncharacterized protein. (287 aa)
	LOC103469311	Zgc:77748. (283 aa)
	LOC103479515	Testis associated actin remodelling kinase 2. (618 aa)
	LOC103465321	Junction plakoglobin a. (721 aa)
	LOC103477155	Platelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family. (560 aa)
	LOC103479675	Rac family small GTPase 2. (192 aa)
	LOC103458988	Uncharacterized protein. (1012 aa)
	ENSPREP00000031580	LIM zinc-binding domain-containing protein. (57 aa)
	LOC103464268	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (211 aa)
	tsc1	TSC complex subunit 1b. (1243 aa)
	LOC103476978	Vinculin a. (1135 aa)
	vtn	Vitronectin a. (568 aa)
	ENSPREP00000032283	EMI domain-containing protein. (303 aa)
	LOC103470992	Uncharacterized protein. (727 aa)
	LOC103470767	Protein kinase domain-containing protein. (707 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARHGAP6	CDC42	ENSPREP00000002674	ENSPREP00000005959	Rho GTPase activating protein 6.	Cell division cycle 42.	0.414
ARHGAP6	LOC103465423	ENSPREP00000002674	ENSPREP00000026666	Rho GTPase activating protein 6.	Cell division cycle 42.	0.414
ARHGAP6	egfl6	ENSPREP00000002674	ENSPREP00000002529	Rho GTPase activating protein 6.	EGF-like-domain, multiple 6.	0.445
CDC42	ARHGAP6	ENSPREP00000005959	ENSPREP00000002674	Cell division cycle 42.	Rho GTPase activating protein 6.	0.414
CDC42	ENSPREP00000029693	ENSPREP00000005959	ENSPREP00000029693	Cell division cycle 42.	Uncharacterized protein.	0.526
CDC42	LOC103457606	ENSPREP00000005959	ENSPREP00000028576	Cell division cycle 42.	Protein tyrosine kinase 2 beta, b; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.492
CDC42	LOC103472469	ENSPREP00000005959	ENSPREP00000017329	Cell division cycle 42.	Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.492
CDC42	LOC103472837	ENSPREP00000005959	ENSPREP00000001820	Cell division cycle 42.	Uncharacterized protein.	0.900
CDC42	LOC103475221	ENSPREP00000005959	ENSPREP00000017059	Cell division cycle 42.	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.492
CDC42	LOC103476978	ENSPREP00000005959	ENSPREP00000032212	Cell division cycle 42.	Vinculin a.	0.417
CDC42	LOC103477991	ENSPREP00000005959	ENSPREP00000017385	Cell division cycle 42.	Uncharacterized protein.	0.901
CDC42	LOC103479675	ENSPREP00000005959	ENSPREP00000000205	Cell division cycle 42.	Rac family small GTPase 2.	0.520
CDC42	LOC103481975	ENSPREP00000005959	ENSPREP00000029641	Cell division cycle 42.	Uncharacterized protein.	0.528
CDC42	LOC103481975-2	ENSPREP00000005959	ENSPREP00000029676	Cell division cycle 42.	Uncharacterized protein.	0.521
CDC42	LOC103481976	ENSPREP00000005959	ENSPREP00000029706	Cell division cycle 42.	Uncharacterized protein.	0.520
CDC42	LOC103482188	ENSPREP00000005959	ENSPREP00000004852	Cell division cycle 42.	Rac family small GTPase 3b.	0.521
CDC42	RAC1	ENSPREP00000005959	ENSPREP00000009664	Cell division cycle 42.	Rac family small GTPase 1.	0.520
CDC42	ptk2	ENSPREP00000005959	ENSPREP00000014357	Cell division cycle 42.	Protein tyrosine kinase 2ab; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.492
CDC42	rasa1	ENSPREP00000005959	ENSPREP00000006300	Cell division cycle 42.	RAS p21 protein activator (GTPase activating protein) 1a.	0.553
CDC42	vcl	ENSPREP00000005959	ENSPREP00000004437	Cell division cycle 42.	Vinculin b.	0.417