(41 nodes) Positive regulation of mitochondrion organization network (Poecilia reticulata)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	pink1	PTEN induced kinase 1. (575 aa)
	ssbp1	Single-stranded DNA binding protein 1. (163 aa)
	BAX	BCL2 associated X, apoptosis regulator. (191 aa)
	mief2	Mitochondrial elongation factor 2. (465 aa)
	pla2g6	Phospholipase A2, group VI (cytosolic, calcium-independent). (821 aa)
	htt	Huntingtin. (3167 aa)
	gsk3b	Glycogen synthase kinase 3 beta, genome duplicate a; Belongs to the protein kinase superfamily. (421 aa)
	zdhhc6	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (412 aa)
	LOC103459210	Decorin; May affect the rate of fibrils formation. (360 aa)
	LOC103462295	Zgc:153993. (263 aa)
	Bcl2l11	Uncharacterized protein. (202 aa)
	vps13d	Vacuolar protein sorting 13 homolog D. (3861 aa)
	pdcd5	Programmed cell death 5. (133 aa)
	LOC103473458	Zgc:73226. (215 aa)
	ENSPREP00000003758	Pyrin domain-containing protein. (110 aa)
	LOC103478486	Uncharacterized protein. (208 aa)
	ENSPREP00000008376	Uncharacterized protein. (208 aa)
	stoml2	Stomatin (EPB72)-like 2. (351 aa)
	fbxo7	F-box protein 7. (465 aa)
	ddhd1	DDHD domain containing 1a. (856 aa)
	LOC103472964	Glycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily. (449 aa)
	LOC103468663	Uncharacterized protein. (200 aa)
	ralbp1	RalA binding protein 1. (664 aa)
	pinlyp	Uncharacterized protein. (208 aa)
	LOC103458422	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (289 aa)
	bnip3	BCL2 interacting protein 3. (178 aa)
	ENSPREP00000020277	RBR-type E3 ubiquitin transferase. (158 aa)
	gsk3a	Glycogen synthase kinase 3 alpha b; Belongs to the protein kinase superfamily. (438 aa)
	ENSPREP00000021691	Uncharacterized protein. (123 aa)
	Mllt11	WRNPLPNID domain-containing protein. (117 aa)
	mff	Mitochondrial fission factor. (234 aa)
	Gper1	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (321 aa)
	mief1	Mitochondrial elongation factor 1. (468 aa)
	pgam5	PGAM family member 5, serine/threonine protein phosphatase, mitochondrial. (351 aa)
	ppargc1a	Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha. (1284 aa)
	bad	BCL2 associated agonist of cell death b. (166 aa)
	fam162a	Family with sequence similarity 162 member A. (142 aa)
	bmf	Uncharacterized protein. (160 aa)
	ambra1	Autophagy/beclin-1 regulator 1b. (1210 aa)
	mul1	Mitochondrial E3 ubiquitin protein ligase 1b. (352 aa)
	vps35	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (798 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BAX	Bcl2l11	ENSPREP00000013021	ENSPREP00000002893	BCL2 associated X, apoptosis regulator.	Uncharacterized protein.	0.990
BAX	LOC103462295	ENSPREP00000013021	ENSPREP00000002464	BCL2 associated X, apoptosis regulator.	Zgc:153993.	0.988
BAX	LOC103468663	ENSPREP00000013021	ENSPREP00000012995	BCL2 associated X, apoptosis regulator.	Uncharacterized protein.	0.903
BAX	bad	ENSPREP00000013021	ENSPREP00000030076	BCL2 associated X, apoptosis regulator.	BCL2 associated agonist of cell death b.	0.739
BAX	bmf	ENSPREP00000013021	ENSPREP00000030451	BCL2 associated X, apoptosis regulator.	Uncharacterized protein.	0.527
Bcl2l11	BAX	ENSPREP00000002893	ENSPREP00000013021	Uncharacterized protein.	BCL2 associated X, apoptosis regulator.	0.990
Bcl2l11	ENSPREP00000021691	ENSPREP00000002893	ENSPREP00000021691	Uncharacterized protein.	Uncharacterized protein.	0.932
Bcl2l11	LOC103462295	ENSPREP00000002893	ENSPREP00000002464	Uncharacterized protein.	Zgc:153993.	0.993
Bcl2l11	LOC103468663	ENSPREP00000002893	ENSPREP00000012995	Uncharacterized protein.	Uncharacterized protein.	0.992
Bcl2l11	bad	ENSPREP00000002893	ENSPREP00000030076	Uncharacterized protein.	BCL2 associated agonist of cell death b.	0.751
Bcl2l11	bmf	ENSPREP00000002893	ENSPREP00000030451	Uncharacterized protein.	Uncharacterized protein.	0.549
ENSPREP00000020277	LOC103472964	ENSPREP00000020277	ENSPREP00000010416	RBR-type E3 ubiquitin transferase.	Glycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily.	0.434
ENSPREP00000020277	LOC103473458	ENSPREP00000020277	ENSPREP00000003690	RBR-type E3 ubiquitin transferase.	Zgc:73226.	0.434
ENSPREP00000020277	ambra1	ENSPREP00000020277	ENSPREP00000030525	RBR-type E3 ubiquitin transferase.	Autophagy/beclin-1 regulator 1b.	0.601
ENSPREP00000020277	bnip3	ENSPREP00000020277	ENSPREP00000018111	RBR-type E3 ubiquitin transferase.	BCL2 interacting protein 3.	0.485
ENSPREP00000020277	fbxo7	ENSPREP00000020277	ENSPREP00000009632	RBR-type E3 ubiquitin transferase.	F-box protein 7.	0.580
ENSPREP00000020277	gsk3a	ENSPREP00000020277	ENSPREP00000020500	RBR-type E3 ubiquitin transferase.	Glycogen synthase kinase 3 alpha b; Belongs to the protein kinase superfamily.	0.434
ENSPREP00000020277	gsk3b	ENSPREP00000020277	ENSPREP00000001029	RBR-type E3 ubiquitin transferase.	Glycogen synthase kinase 3 beta, genome duplicate a; Belongs to the protein kinase superfamily.	0.434
ENSPREP00000020277	htt	ENSPREP00000020277	ENSPREP00000000708	RBR-type E3 ubiquitin transferase.	Huntingtin.	0.674
ENSPREP00000020277	mff	ENSPREP00000020277	ENSPREP00000026065	RBR-type E3 ubiquitin transferase.	Mitochondrial fission factor.	0.413