(33 nodes) Negative regulation of mitochondrion organization network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	VAT1	Vesicle amine transport 1. (438 aa)
	mpv17l	Uncharacterized protein; Belongs to the peroxisomal membrane protein PXMP2/4 family. (210 aa)
	GHITM	Growth hormone inducible transmembrane protein. (353 aa)
	LOC103462295	Zgc:153993. (263 aa)
	LOC103464595	Translocator protein. (147 aa)
	LOC103464594	Translocator protein. (161 aa)
	LOC103473458	Zgc:73226. (215 aa)
	slc25a4	Solute carrier family 25 member 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (308 aa)
	prelid1	PRELI domain containing 1a. (210 aa)
	LOC103466417	PRELI/MSF1 domain-containing protein. (213 aa)
	igf1	Insulin-like growth factor 1. (186 aa)
	LOC103478098	Si:ch211-120k19.1; Belongs to the peroxisomal membrane protein PXMP2/4 family. (187 aa)
	flcn	Folliculin. (554 aa)
	slc35f6	Solute carrier family 35 member F6; May play a role as a nucleotide-sugar transporter. (422 aa)
	LOC103469367	Vesicle amine transport 1. (545 aa)
	slc25a5	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (299 aa)
	LOC103471639	Solute carrier family 25 member 6; Belongs to the mitochondrial carrier (TC 2.A.29) family. (369 aa)
	clg20h11orf65	Uncharacterized protein. (289 aa)
	acaa2	Acetyl-CoA acyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (396 aa)
	bnip3	BCL2 interacting protein 3. (178 aa)
	fxn	Frataxin. (213 aa)
	LOC103469059	Uncharacterized protein; Belongs to the peroxisomal membrane protein PXMP2/4 family. (184 aa)
	ENSPREP00000020277	RBR-type E3 ubiquitin transferase. (158 aa)
	LOC103480947	PRELI domain containing 1b. (192 aa)
	oxt	Arginine vasopressin; Belongs to the vasopressin/oxytocin family. (138 aa)
	psmd10	Proteasome 26S subunit, non-ATPase 10. (226 aa)
	oma1	OMA1 zinc metallopeptidase. (475 aa)
	mul1	Mitochondrial E3 ubiquitin protein ligase 1b. (352 aa)
	LOC103475848	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
	huwe1	HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1. (4580 aa)
	tmem14a	Zgc:163080. (102 aa)
	gclc	Glutamate-cysteine ligase, catalytic subunit. (630 aa)
	pink1	PTEN induced kinase 1. (575 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000020277	LOC103473458	ENSPREP00000020277	ENSPREP00000003690	RBR-type E3 ubiquitin transferase.	Zgc:73226.	0.434
ENSPREP00000020277	bnip3	ENSPREP00000020277	ENSPREP00000018111	RBR-type E3 ubiquitin transferase.	BCL2 interacting protein 3.	0.485
ENSPREP00000020277	fxn	ENSPREP00000020277	ENSPREP00000018219	RBR-type E3 ubiquitin transferase.	Frataxin.	0.468
ENSPREP00000020277	mul1	ENSPREP00000020277	ENSPREP00000031865	RBR-type E3 ubiquitin transferase.	Mitochondrial E3 ubiquitin protein ligase 1b.	0.690
ENSPREP00000020277	pink1	ENSPREP00000020277	ENSPREP00000032869	RBR-type E3 ubiquitin transferase.	PTEN induced kinase 1.	0.996
LOC103469059	mpv17l	ENSPREP00000019598	ENSPREP00000000679	Uncharacterized protein; Belongs to the peroxisomal membrane protein PXMP2/4 family.	Uncharacterized protein; Belongs to the peroxisomal membrane protein PXMP2/4 family.	0.901
LOC103471639	LOC103475848	ENSPREP00000013259	ENSPREP00000034174	Solute carrier family 25 member 6; Belongs to the mitochondrial carrier (TC 2.A.29) family.	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.652
LOC103471639	slc25a4	ENSPREP00000013259	ENSPREP00000007465	Solute carrier family 25 member 6; Belongs to the mitochondrial carrier (TC 2.A.29) family.	Solute carrier family 25 member 4; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.653
LOC103471639	slc25a5	ENSPREP00000013259	ENSPREP00000013235	Solute carrier family 25 member 6; Belongs to the mitochondrial carrier (TC 2.A.29) family.	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.652
LOC103473458	ENSPREP00000020277	ENSPREP00000003690	ENSPREP00000020277	Zgc:73226.	RBR-type E3 ubiquitin transferase.	0.434
LOC103473458	bnip3	ENSPREP00000003690	ENSPREP00000018111	Zgc:73226.	BCL2 interacting protein 3.	0.905
LOC103473458	pink1	ENSPREP00000003690	ENSPREP00000032869	Zgc:73226.	PTEN induced kinase 1.	0.454
LOC103475848	LOC103471639	ENSPREP00000034174	ENSPREP00000013259	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family.	Solute carrier family 25 member 6; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.652
LOC103475848	slc25a4	ENSPREP00000034174	ENSPREP00000007465	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family.	Solute carrier family 25 member 4; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.653
LOC103475848	slc25a5	ENSPREP00000034174	ENSPREP00000013235	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family.	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.653
acaa2	pink1	ENSPREP00000016912	ENSPREP00000032869	Acetyl-CoA acyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.	PTEN induced kinase 1.	0.549
bnip3	ENSPREP00000020277	ENSPREP00000018111	ENSPREP00000020277	BCL2 interacting protein 3.	RBR-type E3 ubiquitin transferase.	0.485
bnip3	LOC103473458	ENSPREP00000018111	ENSPREP00000003690	BCL2 interacting protein 3.	Zgc:73226.	0.905
bnip3	pink1	ENSPREP00000018111	ENSPREP00000032869	BCL2 interacting protein 3.	PTEN induced kinase 1.	0.582
fxn	ENSPREP00000020277	ENSPREP00000018219	ENSPREP00000020277	Frataxin.	RBR-type E3 ubiquitin transferase.	0.468