(40 nodes) Regulation of glucose metabolic process network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	fam3a	Family with sequence similarity 3 member A. (225 aa)
	foxk1	Forkhead box K1. (564 aa)
	c1qtnf6	C1q and TNF related 6b. (260 aa)
	Sirt7	Uncharacterized protein. (134 aa)
	ENSPREP00000001398	Uncharacterized protein. (404 aa)
	pth	Uncharacterized protein. (124 aa)
	sirt1	Sirtuin 1. (677 aa)
	IGFBP4	Insulin like growth factor binding protein 4. (261 aa)
	ddb1	Damage-specific DNA binding protein 1. (1102 aa)
	pdk1	Protein-serine/threonine kinase. (460 aa)
	LOC103460654	Forkhead box K2. (736 aa)
	IGFBP3	Insulin like growth factor binding protein 3. (285 aa)
	LOC103460042	Protein-serine/threonine kinase. (410 aa)
	igf1	Insulin-like growth factor 1. (186 aa)
	ogt	O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1. (1039 aa)
	LOC103463687	Midnolin. (540 aa)
	ENSPREP00000011673	Uncharacterized protein. (487 aa)
	gckr	Uncharacterized protein. (599 aa)
	lepr	Uncharacterized protein. (1121 aa)
	DGKQ	Diacylglycerol kinase. (895 aa)
	LOC103481842	Protein-serine/threonine kinase. (385 aa)
	SOGA1	Suppressor of glucose, autophagy associated 1. (1888 aa)
	LOC103461037	RAN binding protein 2. (2831 aa)
	ENSPREP00000020277	RBR-type E3 ubiquitin transferase. (158 aa)
	ENSPREP00000021170	Uncharacterized protein. (167 aa)
	pdk3	Protein-serine/threonine kinase. (404 aa)
	dusp12	Dual specificity phosphatase 12. (303 aa)
	bckdk	Protein-serine/threonine kinase. (429 aa)
	lcmt1	Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family. (325 aa)
	LOC103481890	Cytochrome c oxidase assembly homolog 11 (yeast). (253 aa)
	foxk2	Uncharacterized protein. (635 aa)
	LOC103479463	Sirtuin 6. (339 aa)
	LOC103468460	E1A binding protein p300 b. (2737 aa)
	acadm	Acyl-CoA dehydrogenase medium chain. (422 aa)
	usp7	Ubiquitin specific peptidase 7 (herpes virus-associated); Belongs to the peptidase C19 family. (1186 aa)
	mlycd	Malonyl-CoA decarboxylase. (503 aa)
	igf2	IlGF domain-containing protein. (223 aa)
	zmpste24	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (471 aa)
	bad	BCL2 associated agonist of cell death b. (166 aa)
	LOC103482005	E1A binding protein p300 a. (2743 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000020277	LOC103461037	ENSPREP00000020277	ENSPREP00000019992	RBR-type E3 ubiquitin transferase.	RAN binding protein 2.	0.456
ENSPREP00000021170	igf1	ENSPREP00000021170	ENSPREP00000010429	Uncharacterized protein.	Insulin-like growth factor 1.	0.549
ENSPREP00000021170	igf2	ENSPREP00000021170	ENSPREP00000029568	Uncharacterized protein.	IlGF domain-containing protein.	0.445
ENSPREP00000021170	lepr	ENSPREP00000021170	ENSPREP00000016138	Uncharacterized protein.	Uncharacterized protein.	0.835
IGFBP3	igf1	ENSPREP00000008366	ENSPREP00000010429	Insulin like growth factor binding protein 3.	Insulin-like growth factor 1.	0.996
IGFBP3	igf2	ENSPREP00000008366	ENSPREP00000029568	Insulin like growth factor binding protein 3.	IlGF domain-containing protein.	0.832
IGFBP4	igf1	ENSPREP00000005562	ENSPREP00000010429	Insulin like growth factor binding protein 4.	Insulin-like growth factor 1.	0.880
IGFBP4	igf2	ENSPREP00000005562	ENSPREP00000029568	Insulin like growth factor binding protein 4.	IlGF domain-containing protein.	0.690
LOC103460654	ogt	ENSPREP00000007894	ENSPREP00000010451	Forkhead box K2.	O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1.	0.703
LOC103461037	ENSPREP00000020277	ENSPREP00000019992	ENSPREP00000020277	RAN binding protein 2.	RBR-type E3 ubiquitin transferase.	0.456
LOC103468460	LOC103482005	ENSPREP00000026558	ENSPREP00000030842	E1A binding protein p300 b.	E1A binding protein p300 a.	0.902
LOC103468460	ddb1	ENSPREP00000026558	ENSPREP00000006475	E1A binding protein p300 b.	Damage-specific DNA binding protein 1.	0.414
LOC103468460	sirt1	ENSPREP00000026558	ENSPREP00000003960	E1A binding protein p300 b.	Sirtuin 1.	0.587
LOC103479463	sirt1	ENSPREP00000026036	ENSPREP00000003960	Sirtuin 6.	Sirtuin 1.	0.879
LOC103482005	LOC103468460	ENSPREP00000030842	ENSPREP00000026558	E1A binding protein p300 a.	E1A binding protein p300 b.	0.902
LOC103482005	ddb1	ENSPREP00000030842	ENSPREP00000006475	E1A binding protein p300 a.	Damage-specific DNA binding protein 1.	0.414
LOC103482005	sirt1	ENSPREP00000030842	ENSPREP00000003960	E1A binding protein p300 a.	Sirtuin 1.	0.587
Sirt7	ddb1	ENSPREP00000000575	ENSPREP00000006475	Uncharacterized protein.	Damage-specific DNA binding protein 1.	0.570
Sirt7	sirt1	ENSPREP00000000575	ENSPREP00000003960	Uncharacterized protein.	Sirtuin 1.	0.799
ddb1	LOC103468460	ENSPREP00000006475	ENSPREP00000026558	Damage-specific DNA binding protein 1.	E1A binding protein p300 b.	0.414