(79 nodes) Positive regulation of neuron projection development network (Poecilia reticulata)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Amigo2	Ig-like domain-containing protein. (517 aa)
	LOC103473427	Rap guanine nucleotide exchange factor (GEF) 1b. (1200 aa)
	ENSPREP00000002283	Uncharacterized protein. (66 aa)
	FIG4	FIG4 phosphoinositide 5-phosphatase. (901 aa)
	ret	Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1118 aa)
	tnn	Tenascin N. (845 aa)
	atoh7	Atonal bHLH transcription factor 7. (133 aa)
	fbxo38	F-box protein 38. (1208 aa)
	ENSPREP00000003856	Arylsulfatase family, member Ia. (426 aa)
	LOC103473467	Tyrosine-protein kinase receptor. (830 aa)
	dhx36	DEAH (Asp-Glu-Ala-His) box polypeptide 36. (1057 aa)
	LOC103468820	BAI1-associated protein 2a. (549 aa)
	LOC103461231	Protein kinase C and casein kinase substrate in neurons 1a. (441 aa)
	eef2k	Eukaryotic elongation factor 2 kinase. (767 aa)
	adnp	Activity-dependent neuroprotector homeobox b. (1057 aa)
	LOC103477848	Apolipoprotein Eb. (265 aa)
	kdm1a	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (855 aa)
	LOC103470450	Si:dkey-40c11.2. (812 aa)
	twf2	Twinfilin actin-binding protein 2a. (349 aa)
	ntrk3	Tyrosine-protein kinase receptor. (815 aa)
	LOC103469263	Parvalbumin 8; Belongs to the parvalbumin family. (109 aa)
	LOC103462684	Neuroplastin b. (379 aa)
	nfe2l2	Nuclear factor, erythroid 2-like 2a. (617 aa)
	nckipsd	NCK interacting protein with SH3 domain. (752 aa)
	LOC103465767	Tyrosine-protein kinase receptor. (826 aa)
	rapgef2	Rap guanine nucleotide exchange factor (GEF) 2. (1615 aa)
	dbnl	Drebrin-like b. (479 aa)
	scarb2	Scavenger receptor class B, member 2a; Belongs to the CD36 family. (530 aa)
	stmn2	Stathmin; Belongs to the stathmin family. (180 aa)
	ENSPREP00000012400	Uncharacterized protein. (550 aa)
	PTK7	Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1042 aa)
	CRTC1	CREB regulated transcription coactivator 1b. (688 aa)
	LOC103473017	Apolipoprotein Ea. (251 aa)
	scn1b	Sodium channel, voltage-gated, type I, beta b. (223 aa)
	psmc3ip	Reticulophagy regulator family member 3. (496 aa)
	LOC103479167	CREB regulated transcription coactivator 1a. (518 aa)
	LOC103473662	Scavenger receptor class B, member 2c; Belongs to the CD36 family. (481 aa)
	twf1	Twinfilin actin-binding protein 1a. (350 aa)
	ENSPREP00000014740	Teneurin N-terminal domain-containing protein. (189 aa)
	LOC103471835	Si:dkey-237h12.3. (2465 aa)
	LOC103478362	Cordon-bleu WH2 repeat protein. (1443 aa)
	ENSPREP00000017955	C1q domain-containing protein. (310 aa)
	fez1	Fasciculation and elongation protein zeta 1 (zygin I). (398 aa)
	dbn1	Drebrin 1. (528 aa)
	LOC103464724	Protein kinase C and casein kinase substrate in neurons 1b. (484 aa)
	amigo1	Adhesion molecule with Ig-like domain 1. (509 aa)
	abl1	Tyrosine-protein kinase. (1124 aa)
	ENSPREP00000021886	Teneurin N-terminal domain-containing protein. (174 aa)
	tenm4	Teneurin transmembrane protein 4. (2526 aa)
	BAIAP2	BAI1 associated protein 2. (569 aa)
	styxl1	Serine/threonine/tyrosine interacting-like 1. (289 aa)
	LOC103466432	Si:ch73-330k17.3. (167 aa)
	LOC103466425	Uncharacterized protein. (380 aa)
	LOC103464180	Uncharacterized protein. (116 aa)
	cux2	Homeobox protein cut-like. (1544 aa)
	caprin1	Cell cycle associated protein 1b. (686 aa)
	ENSPREP00000024427	IGv domain-containing protein. (354 aa)
	RELN	Reelin. (3446 aa)
	LOC103466075	Membrane associated guanylate kinase, WW and PDZ domain containing 2b. (1538 aa)
	TRIM67	Tripartite motif containing 67. (737 aa)
	LOC103467508	Ig-like domain-containing protein. (451 aa)
	ntrk1	Tyrosine-protein kinase receptor. (797 aa)
	sf3a2	Splicing factor 3a, subunit 2. (294 aa)
	LOC103468460	E1A binding protein p300 b. (2737 aa)
	abl2	Tyrosine-protein kinase. (1187 aa)
	ndnf	Neuron-derived neurotrophic factor. (571 aa)
	ARSB	Arylsulfatase B. (523 aa)
	ntrk2	Neurotrophic tyrosine kinase, receptor, type 2a. (469 aa)
	ptpn5	Protein tyrosine phosphatase non-receptor type 5. (570 aa)
	LOC103478616	Stathmin 2a. (225 aa)
	ror1	Receptor tyrosine kinase-like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (953 aa)
	LOC103482005	E1A binding protein p300 a. (2743 aa)
	Amigo3	Adhesion molecule with Ig-like domain 3. (495 aa)
	LOC103480086	Arylsulfatase family, member J. (601 aa)
	scarf1	Scavenger receptor class F, member 1. (894 aa)
	magi2	Membrane associated guanylate kinase, WW and PDZ domain containing 2a. (1287 aa)
	LOC103470599	Uncharacterized protein. (2826 aa)
	creb3l2	cAMP responsive element binding protein 3-like 2. (520 aa)
	LOC103462434	Cell cycle associated protein 1a. (637 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BAIAP2	LOC103468820	ENSPREP00000022196	ENSPREP00000004709	BAI1 associated protein 2.	BAI1-associated protein 2a.	0.901
BAIAP2	abl1	ENSPREP00000022196	ENSPREP00000021197	BAI1 associated protein 2.	Tyrosine-protein kinase.	0.471
BAIAP2	abl2	ENSPREP00000022196	ENSPREP00000026823	BAI1 associated protein 2.	Tyrosine-protein kinase.	0.471
BAIAP2	nckipsd	ENSPREP00000022196	ENSPREP00000008037	BAI1 associated protein 2.	NCK interacting protein with SH3 domain.	0.781
ENSPREP00000012400	fez1	ENSPREP00000012400	ENSPREP00000018236	Uncharacterized protein.	Fasciculation and elongation protein zeta 1 (zygin I).	0.425
ENSPREP00000014740	LOC103471835	ENSPREP00000014740	ENSPREP00000014818	Teneurin N-terminal domain-containing protein.	Si:dkey-237h12.3.	0.898
ENSPREP00000014740	tenm4	ENSPREP00000014740	ENSPREP00000021974	Teneurin N-terminal domain-containing protein.	Teneurin transmembrane protein 4.	0.701
ENSPREP00000017955	LOC103462434	ENSPREP00000017955	ENSPREP00000033928	C1q domain-containing protein.	Cell cycle associated protein 1a.	0.805
ENSPREP00000017955	caprin1	ENSPREP00000017955	ENSPREP00000023944	C1q domain-containing protein.	Cell cycle associated protein 1b.	0.853
ENSPREP00000021886	LOC103471835	ENSPREP00000021886	ENSPREP00000014818	Teneurin N-terminal domain-containing protein.	Si:dkey-237h12.3.	0.899
ENSPREP00000021886	tenm4	ENSPREP00000021886	ENSPREP00000021974	Teneurin N-terminal domain-containing protein.	Teneurin transmembrane protein 4.	0.899
ENSPREP00000024427	scn1b	ENSPREP00000024427	ENSPREP00000013607	IGv domain-containing protein.	Sodium channel, voltage-gated, type I, beta b.	0.910
LOC103462434	ENSPREP00000017955	ENSPREP00000033928	ENSPREP00000017955	Cell cycle associated protein 1a.	C1q domain-containing protein.	0.805
LOC103465767	LOC103473427	ENSPREP00000009310	ENSPREP00000001069	Tyrosine-protein kinase receptor.	Rap guanine nucleotide exchange factor (GEF) 1b.	0.469
LOC103468460	LOC103482005	ENSPREP00000026558	ENSPREP00000030842	E1A binding protein p300 b.	E1A binding protein p300 a.	0.902
LOC103468460	creb3l2	ENSPREP00000026558	ENSPREP00000033704	E1A binding protein p300 b.	cAMP responsive element binding protein 3-like 2.	0.820
LOC103468460	kdm1a	ENSPREP00000026558	ENSPREP00000006670	E1A binding protein p300 b.	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	0.660
LOC103468460	nfe2l2	ENSPREP00000026558	ENSPREP00000007937	E1A binding protein p300 b.	Nuclear factor, erythroid 2-like 2a.	0.750
LOC103468820	BAIAP2	ENSPREP00000004709	ENSPREP00000022196	BAI1-associated protein 2a.	BAI1 associated protein 2.	0.901
LOC103468820	abl1	ENSPREP00000004709	ENSPREP00000021197	BAI1-associated protein 2a.	Tyrosine-protein kinase.	0.471