(28 nodes) Myotube cell development network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSPREP00000002748	Myogenic factor. (237 aa)
	spg11	SPG11 vesicle trafficking associated, spatacsin. (2269 aa)
	LOC103478865	Kelch-like family member 40a. (613 aa)
	gdf5	Growth differentiation factor 5. (484 aa)
	nfatc2	Nuclear factor of activated T cells 2a. (899 aa)
	klhl40	Kelch-like family member 40b. (612 aa)
	selenon	Selenoprotein N. (538 aa)
	HOMER1	Homer scaffold protein 1. (377 aa)
	dner	Delta/notch-like EGF repeat containing. (772 aa)
	LOC103473596	Transmembrane protein 182b. (260 aa)
	six1	SIX homeobox 1a. (284 aa)
	LOC103478252	Growth differentiation factor 6a. (418 aa)
	LOC103465968	Myosin IXAb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2459 aa)
	LOC103474384	Kelch-like family member 41b. (606 aa)
	SMYD3	SET and MYND domain containing 3. (443 aa)
	tmem182	Transmembrane protein 182a. (246 aa)
	shh	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (427 aa)
	LOC103478079	RNA binding protein fox-1 homolog; RNA-binding protein that regulates alternative splicing events. (364 aa)
	ripor2	RHO family interacting cell polarization regulator 2. (1067 aa)
	igf1	Insulin-like growth factor 1. (186 aa)
	bin3	Bridging integrator 3. (248 aa)
	LOC103462133	Myosin IXAa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2310 aa)
	LMOD3	Leiomodin 3. (539 aa)
	smo	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (811 aa)
	klhl41	Kelch-like family member 41a. (598 aa)
	myf5	Myogenic factor. (240 aa)
	ripor3	RIPOR family member 3. (1001 aa)
	LOC103470410	Homer scaffold protein 1b. (402 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC103474384	smo	ENSPREP00000019516	ENSPREP00000005932	Kelch-like family member 41b.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.469
LOC103478865	smo	ENSPREP00000032112	ENSPREP00000005932	Kelch-like family member 40a.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.469
klhl40	smo	ENSPREP00000030886	ENSPREP00000005932	Kelch-like family member 40b.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.469
klhl41	smo	ENSPREP00000004731	ENSPREP00000005932	Kelch-like family member 41a.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.469
shh	smo	ENSPREP00000013208	ENSPREP00000005932	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.809
smo	LOC103474384	ENSPREP00000005932	ENSPREP00000019516	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	Kelch-like family member 41b.	0.469
smo	LOC103478865	ENSPREP00000005932	ENSPREP00000032112	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	Kelch-like family member 40a.	0.469
smo	klhl40	ENSPREP00000005932	ENSPREP00000030886	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	Kelch-like family member 40b.	0.469
smo	klhl41	ENSPREP00000005932	ENSPREP00000004731	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	Kelch-like family member 41a.	0.469
smo	shh	ENSPREP00000005932	ENSPREP00000013208	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.809