(18 nodes) Peroxisomal membrane transport network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	abcd4	ATP-binding cassette, sub-family D (ALD), member 4. (617 aa)
	LOC103460472	Peroxisomal biogenesis factor 5-like b. (563 aa)
	pex19	Peroxisomal biogenesis factor 19. (283 aa)
	pex1	Peroxisomal biogenesis factor 1. (1207 aa)
	abcd3	ATP-binding cassette, sub-family D (ALD), member 3a. (659 aa)
	pex12	Peroxisome assembly protein 12; Required for protein import into peroxisomes. Belongs to the pex2/pex10/pex12 family. (349 aa)
	pex10	Peroxisomal biogenesis factor 10. (323 aa)
	abcd2	ATP-binding cassette, sub-family D (ALD), member 2. (790 aa)
	pex5	Peroxisomal biogenesis factor 5. (639 aa)
	LOC103460228	ATP-binding cassette, sub-family D (ALD), member 1. (785 aa)
	pex3	Peroxisomal biogenesis factor 3. (360 aa)
	pex7	Peroxisomal biogenesis factor 7. (340 aa)
	ENSPREP00000022666	Peroxisomal biogenesis factor 5-like a. (491 aa)
	pex6	Peroxisomal biogenesis factor 6. (1057 aa)
	pex14	Peroxisomal biogenesis factor 14. (374 aa)
	pex2	Peroxisomal biogenesis factor 2. (335 aa)
	fam185a	Family with sequence similarity 185 member A. (386 aa)
	lonp2	Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import; Belongs to the peptidase S16 family. ECO:0000256\|PROSITE-. (837 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000022666	abcd3	ENSPREP00000022666	ENSPREP00000008027	Peroxisomal biogenesis factor 5-like a.	ATP-binding cassette, sub-family D (ALD), member 3a.	0.437
ENSPREP00000022666	fam185a	ENSPREP00000022666	ENSPREP00000024036	Peroxisomal biogenesis factor 5-like a.	Family with sequence similarity 185 member A.	0.883
ENSPREP00000022666	lonp2	ENSPREP00000022666	ENSPREP00000029248	Peroxisomal biogenesis factor 5-like a.	Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import; Belongs to the peptidase S16 family. ECO:0000256\|PROSITE-.	0.654
ENSPREP00000022666	pex1	ENSPREP00000022666	ENSPREP00000006878	Peroxisomal biogenesis factor 5-like a.	Peroxisomal biogenesis factor 1.	0.840
ENSPREP00000022666	pex10	ENSPREP00000022666	ENSPREP00000009344	Peroxisomal biogenesis factor 5-like a.	Peroxisomal biogenesis factor 10.	0.868
ENSPREP00000022666	pex12	ENSPREP00000022666	ENSPREP00000009322	Peroxisomal biogenesis factor 5-like a.	Peroxisome assembly protein 12; Required for protein import into peroxisomes. Belongs to the pex2/pex10/pex12 family.	0.946
ENSPREP00000022666	pex14	ENSPREP00000022666	ENSPREP00000023963	Peroxisomal biogenesis factor 5-like a.	Peroxisomal biogenesis factor 14.	0.955
ENSPREP00000022666	pex19	ENSPREP00000022666	ENSPREP00000001567	Peroxisomal biogenesis factor 5-like a.	Peroxisomal biogenesis factor 19.	0.449
ENSPREP00000022666	pex2	ENSPREP00000022666	ENSPREP00000023986	Peroxisomal biogenesis factor 5-like a.	Peroxisomal biogenesis factor 2.	0.752
ENSPREP00000022666	pex3	ENSPREP00000022666	ENSPREP00000020654	Peroxisomal biogenesis factor 5-like a.	Peroxisomal biogenesis factor 3.	0.516
ENSPREP00000022666	pex6	ENSPREP00000022666	ENSPREP00000029806	Peroxisomal biogenesis factor 5-like a.	Peroxisomal biogenesis factor 6.	0.841
ENSPREP00000022666	pex7	ENSPREP00000022666	ENSPREP00000020948	Peroxisomal biogenesis factor 5-like a.	Peroxisomal biogenesis factor 7.	0.940
LOC103460228	abcd3	ENSPREP00000018941	ENSPREP00000008027	ATP-binding cassette, sub-family D (ALD), member 1.	ATP-binding cassette, sub-family D (ALD), member 3a.	0.788
LOC103460228	abcd4	ENSPREP00000018941	ENSPREP00000029396	ATP-binding cassette, sub-family D (ALD), member 1.	ATP-binding cassette, sub-family D (ALD), member 4.	0.725
LOC103460228	fam185a	ENSPREP00000018941	ENSPREP00000024036	ATP-binding cassette, sub-family D (ALD), member 1.	Family with sequence similarity 185 member A.	0.689
LOC103460228	pex12	ENSPREP00000018941	ENSPREP00000009322	ATP-binding cassette, sub-family D (ALD), member 1.	Peroxisome assembly protein 12; Required for protein import into peroxisomes. Belongs to the pex2/pex10/pex12 family.	0.732
LOC103460228	pex14	ENSPREP00000018941	ENSPREP00000023963	ATP-binding cassette, sub-family D (ALD), member 1.	Peroxisomal biogenesis factor 14.	0.744
LOC103460228	pex19	ENSPREP00000018941	ENSPREP00000001567	ATP-binding cassette, sub-family D (ALD), member 1.	Peroxisomal biogenesis factor 19.	0.836
LOC103460228	pex2	ENSPREP00000018941	ENSPREP00000023986	ATP-binding cassette, sub-family D (ALD), member 1.	Peroxisomal biogenesis factor 2.	0.657
LOC103460228	pex3	ENSPREP00000018941	ENSPREP00000020654	ATP-binding cassette, sub-family D (ALD), member 1.	Peroxisomal biogenesis factor 3.	0.792