(67 nodes) Nuclear matrix network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Cfl1	Cofilin 1; Belongs to the actin-binding proteins ADF family. (180 aa)
	cxxc1	CXXC finger protein 1b. (569 aa)
	gfi1b	Growth factor independent 1B transcription repressor. (330 aa)
	LOC103470979	Teneurin transmembrane protein 1. (2672 aa)
	chmp1a	Charged multivesicular body protein 1A. (198 aa)
	cask	Uncharacterized protein; Belongs to the MAGUK family. (884 aa)
	phf5a	PHD finger protein 5A. (110 aa)
	phb2	Prohibitin. (324 aa)
	LOC103478620	Ataxin 1b. (825 aa)
	numa1	Calponin-homology (CH) domain-containing protein. (2143 aa)
	satb2	SATB homeobox 2. (813 aa)
	ogg1	8-oxoguanine DNA glycosylase. (388 aa)
	hnrnpm	Heterogeneous nuclear ribonucleoprotein M. (723 aa)
	LOC103466054	DUF3736 domain-containing protein. (1150 aa)
	LOC103469569	NMDA receptor synaptonuclear signaling and neuronal migration factor b. (472 aa)
	pola1	DNA polymerase. (1478 aa)
	nufip1	C2H2-type domain-containing protein. (533 aa)
	gfi1	Growth factor independent 1A transcription repressor b. (389 aa)
	gse1	Gse1 coiled-coil protein. (2129 aa)
	LOC103460221	CXXC finger protein 1a. (599 aa)
	LOC103478347	RAD21 cohesin complex component a. (637 aa)
	LOC103471901	RRM domain-containing protein. (626 aa)
	ahctf1	AT hook containing transcription factor 1. (1119 aa)
	DGKQ	Diacylglycerol kinase. (895 aa)
	maea	Macrophage erythroblast attacher. (396 aa)
	ENSPREP00000015401	CENP-F_N domain-containing protein. (75 aa)
	DCAF7	DDB1 and CUL4 associated factor 7. (342 aa)
	ENSPREP00000028517	ANK_REP_REGION domain-containing protein. (336 aa)
	LOC103473319	C2H2-type domain-containing protein. (515 aa)
	LOC103457804	Proteasome subunit alpha type. (246 aa)
	xpot	Exportin-T; tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Belongs to the exportin family. (951 aa)
	snw1	SNW domain containing 1. (536 aa)
	kin	Kin17 DNA and RNA binding protein. (396 aa)
	ercc8	Excision repair cross-complementation group 8. (401 aa)
	LOC103469771	Zinc finger protein 703. (579 aa)
	HLCS	Holocarboxylase synthetase. (912 aa)
	LOC103476389	Paraspeckle component 1. (517 aa)
	fign	Fidgetin; Belongs to the AAA ATPase family. (752 aa)
	blm	BLM RecQ like helicase. (1399 aa)
	nsmf	NMDA receptor synaptonuclear signaling and neuronal migration factor a. (623 aa)
	thoc1	THO complex 1. (654 aa)
	ENSPREP00000006614	Prohibitin. (84 aa)
	hat1	Histone acetyltransferase type B catalytic subunit; Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. (379 aa)
	Nono	Non-POU domain containing, octamer-binding. (443 aa)
	LOC103475843	Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family. (950 aa)
	psma6	Proteasome subunit alpha type. (254 aa)
	prpf40a	PRP40 pre-mRNA processing factor 40 homolog A. (883 aa)
	atxn1	Ataxin 1a. (795 aa)
	LOC103474855	Proteasome endopeptidase complex. (248 aa)
	sfpq	Splicing factor proline/glutamine-rich. (709 aa)
	GFI1	Growth factor independent 1 transcriptional repressor. (380 aa)
	LOC103467593	AXH domain-containing protein. (675 aa)
	LOC103477860	SATB homeobox 1b. (872 aa)
	men1	Multiple endocrine neoplasia I. (627 aa)
	Cfl2	Cofilin 2 (muscle); Belongs to the actin-binding proteins ADF family. (187 aa)
	LOC103466879	Keratin 8; Belongs to the intermediate filament family. (535 aa)
	ENSPREP00000004004	THAP-type domain-containing protein. (222 aa)
	LOC103467726	RAD21 cohesin complex component like 1. (539 aa)
	LOC103472890	RAD21 cohesin complex component b. (644 aa)
	LOC103467741	DNA (cytosine-5-)-methyltransferase 3 beta, duplicate a; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1451 aa)
	tep1	Uncharacterized protein. (2622 aa)
	ENSPREP00000002337	Uncharacterized protein. (128 aa)
	LOC103464940	Zgc:158846; Belongs to the intermediate filament family. (532 aa)
	LOC103464941	Keratin 4; Belongs to the intermediate filament family. (474 aa)
	LOC103467753	CCAAT enhancer binding protein beta. (285 aa)
	morc2	MORC family CW-type zinc finger 2. (1050 aa)
	smc3	Structural maintenance of chromosomes protein. (1225 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cfl1	Cfl2	ENSPREP00000012892	ENSPREP00000005445	Cofilin 1; Belongs to the actin-binding proteins ADF family.	Cofilin 2 (muscle); Belongs to the actin-binding proteins ADF family.	0.901
Cfl2	Cfl1	ENSPREP00000005445	ENSPREP00000012892	Cofilin 2 (muscle); Belongs to the actin-binding proteins ADF family.	Cofilin 1; Belongs to the actin-binding proteins ADF family.	0.901
DCAF7	LOC103469771	ENSPREP00000015057	ENSPREP00000025752	DDB1 and CUL4 associated factor 7.	Zinc finger protein 703.	0.440
DCAF7	ercc8	ENSPREP00000015057	ENSPREP00000026087	DDB1 and CUL4 associated factor 7.	Excision repair cross-complementation group 8.	0.836
DCAF7	tep1	ENSPREP00000015057	ENSPREP00000002368	DDB1 and CUL4 associated factor 7.	Uncharacterized protein.	0.590
ENSPREP00000028517	LOC103475843	ENSPREP00000028517	ENSPREP00000013706	ANK_REP_REGION domain-containing protein.	Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family.	0.652
ENSPREP00000028517	blm	ENSPREP00000028517	ENSPREP00000011311	ANK_REP_REGION domain-containing protein.	BLM RecQ like helicase.	0.404
ENSPREP00000028517	cask	ENSPREP00000028517	ENSPREP00000030734	ANK_REP_REGION domain-containing protein.	Uncharacterized protein; Belongs to the MAGUK family.	0.652
ENSPREP00000028517	men1	ENSPREP00000028517	ENSPREP00000005615	ANK_REP_REGION domain-containing protein.	Multiple endocrine neoplasia I.	0.447
ENSPREP00000028517	tep1	ENSPREP00000028517	ENSPREP00000002368	ANK_REP_REGION domain-containing protein.	Uncharacterized protein.	0.865
LOC103466054	tep1	ENSPREP00000023352	ENSPREP00000002368	DUF3736 domain-containing protein.	Uncharacterized protein.	0.450
LOC103467726	LOC103472890	ENSPREP00000003268	ENSPREP00000002991	RAD21 cohesin complex component like 1.	RAD21 cohesin complex component b.	0.904
LOC103467726	LOC103478347	ENSPREP00000003268	ENSPREP00000018269	RAD21 cohesin complex component like 1.	RAD21 cohesin complex component a.	0.904
LOC103467726	pola1	ENSPREP00000003268	ENSPREP00000021442	RAD21 cohesin complex component like 1.	DNA polymerase.	0.430
LOC103467726	smc3	ENSPREP00000003268	ENSPREP00000000387	RAD21 cohesin complex component like 1.	Structural maintenance of chromosomes protein.	0.994
LOC103469771	DCAF7	ENSPREP00000025752	ENSPREP00000015057	Zinc finger protein 703.	DDB1 and CUL4 associated factor 7.	0.440
LOC103469771	tep1	ENSPREP00000025752	ENSPREP00000002368	Zinc finger protein 703.	Uncharacterized protein.	0.426
LOC103471901	Nono	ENSPREP00000017518	ENSPREP00000014821	RRM domain-containing protein.	Non-POU domain containing, octamer-binding.	0.523
LOC103471901	hnrnpm	ENSPREP00000017518	ENSPREP00000023868	RRM domain-containing protein.	Heterogeneous nuclear ribonucleoprotein M.	0.624
LOC103472890	LOC103467726	ENSPREP00000002991	ENSPREP00000003268	RAD21 cohesin complex component b.	RAD21 cohesin complex component like 1.	0.904