(69 nodes) Oxidoreductase activity, acting on the CH-CH group of donors network (Poecilia reticulata)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSPREP00000029837	Uncharacterized protein. (88 aa)
	tecr	Trans-2,3-enoyl-CoA reductase b. (342 aa)
	LOC103479501	Succinate dehydrogenase complex, subunit C, integral membrane protein. (153 aa)
	LOC103465591	Zgc:113054. (551 aa)
	dus2	Dihydrouridine synthase 2. (482 aa)
	LOC103470362	Uncharacterized protein. (625 aa)
	LOC103456937	Carrier domain-containing protein. (2076 aa)
	LOC103456785	Si:dkey-61p9.11. (2009 aa)
	LOC103472917	Carnitine O-acetyltransferase b. (526 aa)
	LOC103472241	Zgc:85777. (434 aa)
	acox3	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (692 aa)
	dhcr7	7-dehydrocholesterol reductase. (491 aa)
	ptges2	Prostaglandin E synthase 2-like. (389 aa)
	fasn	Coiled-coil domain containing 57. (2516 aa)
	rsad1	Radical S-adenosyl methionine domain-containing protein; May be a heme chaperone, appears to bind heme. Homologous bacterial proteins do not have oxygen-independent coproporphyrinogen- III oxidase activity. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L- methionine; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (440 aa)
	LOC103475970	Prostaglandin reductase 1. (307 aa)
	LOC103475975	Prostaglandin reductase 1. (329 aa)
	acaa1	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (419 aa)
	LOC103471931	3-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (251 aa)
	LOC103465156	Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (290 aa)
	mecr	Mitochondrial trans-2-enoyl-CoA reductase. (367 aa)
	ENSPREP00000007883	Dihydrodiol dehydrogenase (dimeric), like. (272 aa)
	tm7sf2	Transmembrane 7 superfamily member 2. (424 aa)
	LOC103462676	Uncharacterized protein. (1003 aa)
	LOC103477241	3-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (252 aa)
	dus1l	Dihydrouridine synthase 1-like (S. cerevisiae). (491 aa)
	acadsb	Acyl-CoA dehydrogenase short/branched chain. (432 aa)
	ENSPREP00000011372	Carn_acyltransf domain-containing protein. (104 aa)
	ENSPREP00000011404	Carn_acyltransf domain-containing protein; Belongs to the carnitine/choline acetyltransferase family. (338 aa)
	ENSPREP00000013371	Uncharacterized protein. (638 aa)
	RETSAT	Retinol saturase. (610 aa)
	acad11	Acyl-CoA dehydrogenase family, member 11. (758 aa)
	bdh2	3-hydroxybutyrate dehydrogenase, type 2. (282 aa)
	LOC103482281	Trans-2,3-enoyl-CoA reductase-like 2a. (290 aa)
	SDHB	Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (339 aa)
	acad8	Acyl-CoA dehydrogenase family, member 8. (419 aa)
	LOC103470626	Zgc:154046; Belongs to the carnitine/choline acetyltransferase family. (628 aa)
	blvra	Biliverdin reductase A. (323 aa)
	acadvl	Acyl-CoA dehydrogenase very long chain. (658 aa)
	dus3l	tRNA-dihydrouridine(47) synthase [NAD(P)(+)]. (639 aa)
	ptgr2	Prostaglandin reductase 2. (347 aa)
	GCDH	Glutaryl-CoA dehydrogenase b. (447 aa)
	ENSPREP00000020110	Si:dkey-61n16.5. (121 aa)
	LOC103461005	S5A_REDUCTASE domain-containing protein. (158 aa)
	sdha	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (663 aa)
	acads	Acyl-CoA dehydrogenase short chain. (405 aa)
	ZADH2	Zinc binding alcohol dehydrogenase domain containing 2. (412 aa)
	dpyd	Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. (1025 aa)
	ENSPREP00000023041	Coproporphyrinogen oxidase. (367 aa)
	ENSPREP00000023115	Coproporphyrinogen oxidase. (311 aa)
	LOC103464182	Coproporphyrinogen oxidase. (278 aa)
	decr1	2,4-dienoyl CoA reductase 1, mitochondrial. (362 aa)
	ivd	Isovaleryl-CoA dehydrogenase. (417 aa)
	srd5a1	3-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (265 aa)
	ppox	Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (476 aa)
	acadm	Acyl-CoA dehydrogenase medium chain. (422 aa)
	decr2	2,4-dienoyl CoA reductase 2, peroxisomal. (299 aa)
	blvrb	Biliverdin reductase B. (205 aa)
	srd5a3	Steroid 5 alpha-reductase 3. (350 aa)
	acox1	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (661 aa)
	ENSPREP00000029984	Tudor domain-containing protein. (152 aa)
	Lbr	Uncharacterized protein. (110 aa)
	acad9	Acyl-CoA dehydrogenase family, member 9. (630 aa)
	dhcr24	24-dehydrocholesterol reductase. (517 aa)
	tbxas1	Thromboxane A synthase 1 (platelet); Belongs to the cytochrome P450 family. (524 aa)
	pecr	Peroxisomal trans-2-enoyl-CoA reductase. (298 aa)
	dus4l	tRNA-dihydrouridine synthase; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs; Belongs to the dus family. (316 aa)
	LOC103467789	Si:ch211-210c8.6. (273 aa)
	dhodh	Dihydroorotate dehydrogenase. (399 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000007883	blvrb	ENSPREP00000007883	ENSPREP00000028178	Dihydrodiol dehydrogenase (dimeric), like.	Biliverdin reductase B.	0.442
ENSPREP00000011372	LOC103470626	ENSPREP00000011372	ENSPREP00000017433	Carn_acyltransf domain-containing protein.	Zgc:154046; Belongs to the carnitine/choline acetyltransferase family.	0.902
ENSPREP00000011372	acaa1	ENSPREP00000011372	ENSPREP00000006361	Carn_acyltransf domain-containing protein.	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	0.496
ENSPREP00000011372	acadm	ENSPREP00000011372	ENSPREP00000027231	Carn_acyltransf domain-containing protein.	Acyl-CoA dehydrogenase medium chain.	0.407
ENSPREP00000011372	acox1	ENSPREP00000011372	ENSPREP00000029304	Carn_acyltransf domain-containing protein.	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	0.677
ENSPREP00000011372	acox3	ENSPREP00000011372	ENSPREP00000004131	Carn_acyltransf domain-containing protein.	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	0.409
ENSPREP00000011372	ivd	ENSPREP00000011372	ENSPREP00000024555	Carn_acyltransf domain-containing protein.	Isovaleryl-CoA dehydrogenase.	0.440
ENSPREP00000011404	acaa1	ENSPREP00000011404	ENSPREP00000006361	Carn_acyltransf domain-containing protein; Belongs to the carnitine/choline acetyltransferase family.	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	0.496
ENSPREP00000011404	acadm	ENSPREP00000011404	ENSPREP00000027231	Carn_acyltransf domain-containing protein; Belongs to the carnitine/choline acetyltransferase family.	Acyl-CoA dehydrogenase medium chain.	0.407
ENSPREP00000011404	acox1	ENSPREP00000011404	ENSPREP00000029304	Carn_acyltransf domain-containing protein; Belongs to the carnitine/choline acetyltransferase family.	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	0.677
ENSPREP00000011404	acox3	ENSPREP00000011404	ENSPREP00000004131	Carn_acyltransf domain-containing protein; Belongs to the carnitine/choline acetyltransferase family.	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	0.409
ENSPREP00000011404	ivd	ENSPREP00000011404	ENSPREP00000024555	Carn_acyltransf domain-containing protein; Belongs to the carnitine/choline acetyltransferase family.	Isovaleryl-CoA dehydrogenase.	0.440
ENSPREP00000020110	LOC103456785	ENSPREP00000020110	ENSPREP00000001717	Si:dkey-61n16.5.	Si:dkey-61p9.11.	0.410
ENSPREP00000020110	LOC103456937	ENSPREP00000020110	ENSPREP00000001701	Si:dkey-61n16.5.	Carrier domain-containing protein.	0.410
ENSPREP00000020110	acaa1	ENSPREP00000020110	ENSPREP00000006361	Si:dkey-61n16.5.	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	0.727
ENSPREP00000020110	acad11	ENSPREP00000020110	ENSPREP00000013666	Si:dkey-61n16.5.	Acyl-CoA dehydrogenase family, member 11.	0.567
ENSPREP00000020110	fasn	ENSPREP00000020110	ENSPREP00000005709	Si:dkey-61n16.5.	Coiled-coil domain containing 57.	0.410
ENSPREP00000023041	dhodh	ENSPREP00000023041	ENSPREP00000033422	Coproporphyrinogen oxidase.	Dihydroorotate dehydrogenase.	0.417
ENSPREP00000023041	dpyd	ENSPREP00000023041	ENSPREP00000021733	Coproporphyrinogen oxidase.	Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family.	0.407
ENSPREP00000023041	ppox	ENSPREP00000023041	ENSPREP00000026836	Coproporphyrinogen oxidase.	Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.	0.873