STRINGSTRING
pigl pigl gls2 gls2 gda gda LOC103475383 LOC103475383 LOC103479554 LOC103479554 aspa aspa hdac5 hdac5 mblac2 mblac2 LOC103466257 LOC103466257 LOC103481546 LOC103481546 ccdc96 ccdc96 dpysl3 dpysl3 acer2 acer2 LOC103474747 LOC103474747 pm20d1 pm20d1 AMPD2 AMPD2 LOC103465759 LOC103465759 faah2 faah2 LOC103472253 LOC103472253 ENSPREP00000004578 ENSPREP00000004578 adat1 adat1 ENSPREP00000004470 ENSPREP00000004470 nit1 nit1 sirt1 sirt1 LOC103464914 LOC103464914 LOC103462569 LOC103462569 LOC103462567 LOC103462567 sirt4 sirt4 LOC103472916 LOC103472916 asah1 asah1 Sirt7 Sirt7 afmid afmid ntan1 ntan1 acy1 acy1 LOC103459339 LOC103459339 LOC103459328 LOC103459328 LOC103461842 LOC103461842 ENSPREP00000001718 ENSPREP00000001718 LOC103467053 LOC103467053 LOC103458631 LOC103458631 ENSPREP00000002543 ENSPREP00000002543 LOC103464932 LOC103464932 hdac9 hdac9 ampd3 ampd3 LOC103459168 LOC103459168 dclre1b dclre1b dhodh dhodh dclre1a dclre1a amdhd1 amdhd1 LOC103477017 LOC103477017 nadsyn1 nadsyn1 agmat agmat LOC103474003 LOC103474003 ENSPREP00000031524 ENSPREP00000031524 LOC103457187 LOC103457187 LOC103465514 LOC103465514 mthfd2 mthfd2 DDAH1 DDAH1 pdf pdf HDAC2 HDAC2 RIDA RIDA ada ada hdac11 hdac11 LOC103481179 LOC103481179 ADARB2 ADARB2 LOC103457580 LOC103457580 apobec2 apobec2 atic atic LOC103458523 LOC103458523 hdac10 hdac10 LOC103468491 LOC103468491 gch1 gch1 LOC103477529 LOC103477529 LOC103467691 LOC103467691 nit2 nit2 LOC103479463 LOC103479463 adar adar LOC103466083 LOC103466083 ENSPREP00000025121 ENSPREP00000025121 LOC103472045 LOC103472045 LOC103461731 LOC103461731 LOC103460190 LOC103460190 upb1 upb1 LOC103482088 LOC103482088 dpysl5 dpysl5 LOC103481893 LOC103481893 dpys dpys adal adal LOC103464825 LOC103464825 wdyhv1 wdyhv1 LOC103458374 LOC103458374 allc allc LOC103467180 LOC103467180 LOC103463959 LOC103463959 oplah oplah ACY3 ACY3 adat2 adat2 LOC103468351 LOC103468351 ngly1 ngly1 padi2 padi2 hint3 hint3 LOC103474968 LOC103474968 HDAC4 HDAC4 hdac6 hdac6 lacc1 lacc1 ampd1 ampd1 amdhd2 amdhd2 aspg aspg cdadc1 cdadc1 LOC103480533 LOC103480533 hdac8 hdac8 faah faah acer3 acer3 LOC103469355 LOC103469355 asrgl1 asrgl1 aga aga sirt5 sirt5 LOC103469985 LOC103469985 arg2 arg2 aicda aicda sirt2 sirt2 acer1 acer1 LOC103472437 LOC103472437 DPYSL2 DPYSL2 LOC103460744 LOC103460744 adad1 adad1 adarb2 adarb2
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
piglPhosphatidylinositol glycan anchor biosynthesis, class L. (283 aa)
gls2Glutaminase 2a (liver, mitochondrial). (600 aa)
gdaGuanine deaminase. (482 aa)
LOC103475383Adenosine deaminase domain containing 2. (624 aa)
LOC103479554NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. (315 aa)
aspaAspartoacylase. (317 aa)
hdac5Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1136 aa)
mblac2Metallo-beta-lactamase domain containing 2. (276 aa)
LOC103466257Aspartoacylase (aminocyclase) 3, tandem duplicate 2. (308 aa)
LOC103481546GTP cyclohydrolase 2. (236 aa)
ccdc96DUF4201 domain-containing protein. (451 aa)
dpysl3Dihydropyrimidinase like 3. (565 aa)
acer2Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (275 aa)
LOC103474747Peptidoglycan-recognition protein; Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Involved in innate immunity. (203 aa)
pm20d1Peptidase M20 domain containing 1, tandem duplicate 2. (520 aa)
AMPD2AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (943 aa)
LOC103465759AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (641 aa)
faah2Fatty acid amide hydrolase 2b. (623 aa)
LOC103472253Biotinidase. (368 aa)
ENSPREP00000004578CN hydrolase domain-containing protein. (404 aa)
adat1Adenosine deaminase tRNA specific 1. (610 aa)
ENSPREP00000004470Uncharacterized protein. (64 aa)
nit1Nitrilase 1. (318 aa)
sirt1Sirtuin 1. (677 aa)
LOC103464914Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (170 aa)
LOC1034625695-hydroxyisourate hydrolase; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. (121 aa)
LOC1034625675-hydroxyisourate hydrolase; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. (132 aa)
sirt4NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily. (311 aa)
LOC103472916Dimethylarginine dimethylaminohydrolase 2. (265 aa)
asah1N-acylsphingosine amidohydrolase (acid ceramidase) 1a; Belongs to the acid ceramidase family. (427 aa)
Sirt7Uncharacterized protein. (134 aa)
afmidKynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. (292 aa)
ntan1Uncharacterized protein. (307 aa)
acy1Aminoacylase 1. (419 aa)
LOC103459339Immunoglobulin superfamily, member 3. (1054 aa)
LOC103459328Uncharacterized protein. (991 aa)
LOC103461842EF-hand_14 domain-containing protein. (563 aa)
ENSPREP00000001718Uncharacterized protein. (156 aa)
LOC103467053Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (821 aa)
LOC103458631Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa)
ENSPREP00000002543Uncharacterized protein. (106 aa)
LOC103464932Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (923 aa)
hdac9Histone deacetylase 9b. (631 aa)
ampd3Adenosine monophosphate deaminase 3a. (617 aa)
LOC103459168Adenosine deaminase 2b. (485 aa)
dclre1bDNA cross-link repair 1B. (566 aa)
dhodhDihydroorotate dehydrogenase. (399 aa)
dclre1aDNA cross-link repair 1A (PSO2 homolog, S. cerevisiae). (895 aa)
amdhd1Amidohydrolase domain containing 1. (432 aa)
LOC103477017Si:dkey-103j14.5. (311 aa)
nadsyn1Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. (663 aa)
agmatAgmatine ureohydrolase (agmatinase); Belongs to the arginase family. (358 aa)
LOC103474003Dihydropyrimidinase like 2b. (575 aa)
ENSPREP00000031524Uncharacterized protein. (156 aa)
LOC103457187Glutaminase a. (617 aa)
LOC103465514Uncharacterized protein; Belongs to the acid ceramidase family. (357 aa)
mthfd2Uncharacterized protein. (338 aa)
DDAH1Dimethylarginine dimethylaminohydrolase 1. (138 aa)
pdfPeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins; Belongs to the polypeptide deformylase family. (270 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (458 aa)
RIDAReactive intermediate imine deaminase A homolog. (136 aa)
adaAdenosine deaminase. (399 aa)
hdac11Histone deacetylase 11. (367 aa)
LOC103481179Adenosine deaminase 2a. (516 aa)
ADARB2Uncharacterized protein. (680 aa)
LOC103457580HIT domain-containing protein. (160 aa)
apobec2Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2b. (306 aa)
atic5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. (591 aa)
LOC103458523Zgc:194887. (279 aa)
hdac10Histone deacetylase 10. (665 aa)
LOC103468491Si:ch211-256m1.8. (1577 aa)
gch1GTP cyclohydrolase 1. (255 aa)
LOC103477529Uncharacterized protein. (749 aa)
LOC103467691Peptidoglycan recognition protein 2. (489 aa)
nit2Nitrilase family, member 2. (269 aa)
LOC103479463Sirtuin 6. (339 aa)
adarAdenosine deaminase RNA specific. (1358 aa)
LOC103466083Si:dkey-103i16.6. (445 aa)
ENSPREP00000025121Sirtuin 3. (152 aa)
LOC103472045Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
LOC103461731Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1063 aa)
LOC103460190Adenosine deaminase RNA specific B1b. (727 aa)
upb1Ureidopropionase, beta. (383 aa)
LOC103482088Neutral ceramidase. (611 aa)
dpysl5Dihydropyrimidinase like 5b. (554 aa)
LOC103481893Arginase. (371 aa)
dpysDihydropyrimidinase. (492 aa)
adalAdenosine deaminase-like. (353 aa)
LOC103464825Glutaminase 2b (liver, mitochondrial). (514 aa)
wdyhv1WDYHV motif containing 1. (194 aa)
LOC103458374Dihydropyrimidinase like 5a. (564 aa)
allcAllantoicase. (382 aa)
LOC103467180AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (835 aa)
LOC103463959Zgc:103559. (450 aa)
oplah5-oxoprolinase, ATP-hydrolysing. (1312 aa)
ACY3Aminoacylase 3. (330 aa)
adat2CMP/dCMP-type deaminase domain-containing protein. (274 aa)
LOC103468351Peptidoglycan recognition protein 6. (477 aa)
ngly1N-glycanase 1. (635 aa)
padi2Peptidyl arginine deiminase, type II. (684 aa)
hint3Histidine triad nucleotide binding protein 3. (167 aa)
LOC103474968Histone deacetylase 12. (345 aa)
HDAC4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1105 aa)
hdac6Histone deacetylase 6. (899 aa)
lacc1Laccase (multicopper oxidoreductase) domain containing 1. (429 aa)
ampd1AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (726 aa)
amdhd2N-acetylglucosamine-6-phosphate deacetylase; Belongs to the metallo-dependent hydrolases superfamily. NagA family. (406 aa)
aspgAsparaginase homolog (S. cerevisiae). (632 aa)
cdadc1Cytidine and dCMP deaminase domain containing 1. (461 aa)
LOC103480533Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (133 aa)
hdac8Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (435 aa)
faahFatty acid amide hydrolase. (587 aa)
acer3Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (267 aa)
LOC103469355Collapsin response mediator protein 1. (676 aa)
asrgl1Asparaginase like 1. (346 aa)
agaAspartylglucosaminidase. (323 aa)
sirt5NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. (326 aa)
LOC103469985Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like. (398 aa)
arg2Arginase. (346 aa)
aicdaActivation-induced cytidine deaminase. (211 aa)
sirt2NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (385 aa)
acer1Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (275 aa)
LOC103472437Reactive intermediate imine deaminase A homolog. (137 aa)
DPYSL2Dihydropyrimidinase like 2. (580 aa)
LOC103460744Dihydropyrimidinase like 4. (648 aa)
adad1Adenosine deaminase domain containing 1 (testis-specific). (536 aa)
adarb2Adenosine deaminase RNA specific B2 (inactive). (766 aa)
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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