(20 nodes) Retinal binding network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	crabp2	Cellular retinoic acid binding protein 2, b; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (142 aa)
	ENSPREP00000028482	Uncharacterized protein. (587 aa)
	LOC103469718	Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (195 aa)
	opn5	Opsin 5; Belongs to the G-protein coupled receptor 1 family. (352 aa)
	LOC103482020	Retinol binding protein 3. (617 aa)
	Rbp3	Interphotoreceptor retinoid-binding protein like. (910 aa)
	rbp4	Retinol binding protein 4, plasma; Belongs to the calycin superfamily. Lipocalin family. (199 aa)
	LOC103479798	Apolipoprotein Da, duplicate 2; Belongs to the calycin superfamily. Lipocalin family. (189 aa)
	LOC103479320	Retinol binding protein 1, cellular, tandem duplicate 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (171 aa)
	LOC103479803	Apolipoprotein Da, duplicate 2; Belongs to the calycin superfamily. Lipocalin family. (190 aa)
	crabp1	Cellular retinoic acid binding protein 1a; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (137 aa)
	rbp2	Retinol binding protein 2a, cellular; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (135 aa)
	stra6	Stimulated by retinoic acid 6. (666 aa)
	LOC103473653	Retinol binding protein 4, like; Belongs to the calycin superfamily. Lipocalin family. (196 aa)
	CRABP1	Cellular retinoic acid binding protein 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (138 aa)
	opn3	Opsin 3. (490 aa)
	RHO	Extra-ocular rhodopsin. (391 aa)
	rho	Rhodopsin; Photoreceptor required for image-forming vision at low light intensity. While most salt water fish species use retinal as chromophore, most freshwater fish use 3-dehydroretinal, or a mixture of retinal and 3-dehydroretinal (By similarity). Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins. Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by arrestin and terminates signaling (By similarity). (350 aa)
	LOC103457850	Opsin 8, group member b; Belongs to the G-protein coupled receptor 1 family. Opsin subfamily. (345 aa)
	LOC103478736	Cellular retinoic acid binding protein 2, a; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (142 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000028482	LOC103479320	ENSPREP00000028482	ENSPREP00000020911	Uncharacterized protein.	Retinol binding protein 1, cellular, tandem duplicate 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.	0.766
ENSPREP00000028482	LOC103479798	ENSPREP00000028482	ENSPREP00000020354	Uncharacterized protein.	Apolipoprotein Da, duplicate 2; Belongs to the calycin superfamily. Lipocalin family.	0.409
ENSPREP00000028482	LOC103479803	ENSPREP00000028482	ENSPREP00000020338	Uncharacterized protein.	Apolipoprotein Da, duplicate 2; Belongs to the calycin superfamily. Lipocalin family.	0.409
ENSPREP00000028482	rbp4	ENSPREP00000028482	ENSPREP00000033535	Uncharacterized protein.	Retinol binding protein 4, plasma; Belongs to the calycin superfamily. Lipocalin family.	0.804
LOC103457850	opn3	ENSPREP00000024988	ENSPREP00000004166	Opsin 8, group member b; Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.	Opsin 3.	0.470
LOC103479320	ENSPREP00000028482	ENSPREP00000020911	ENSPREP00000028482	Retinol binding protein 1, cellular, tandem duplicate 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.	Uncharacterized protein.	0.766
LOC103479320	rbp4	ENSPREP00000020911	ENSPREP00000033535	Retinol binding protein 1, cellular, tandem duplicate 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.	Retinol binding protein 4, plasma; Belongs to the calycin superfamily. Lipocalin family.	0.730
LOC103479320	stra6	ENSPREP00000020911	ENSPREP00000014443	Retinol binding protein 1, cellular, tandem duplicate 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.	Stimulated by retinoic acid 6.	0.766
LOC103479798	ENSPREP00000028482	ENSPREP00000020354	ENSPREP00000028482	Apolipoprotein Da, duplicate 2; Belongs to the calycin superfamily. Lipocalin family.	Uncharacterized protein.	0.409
LOC103479798	stra6	ENSPREP00000020354	ENSPREP00000014443	Apolipoprotein Da, duplicate 2; Belongs to the calycin superfamily. Lipocalin family.	Stimulated by retinoic acid 6.	0.409
LOC103479803	ENSPREP00000028482	ENSPREP00000020338	ENSPREP00000028482	Apolipoprotein Da, duplicate 2; Belongs to the calycin superfamily. Lipocalin family.	Uncharacterized protein.	0.409
LOC103479803	stra6	ENSPREP00000020338	ENSPREP00000014443	Apolipoprotein Da, duplicate 2; Belongs to the calycin superfamily. Lipocalin family.	Stimulated by retinoic acid 6.	0.409
LOC103482020	RHO	ENSPREP00000031549	ENSPREP00000022363	Retinol binding protein 3.	Extra-ocular rhodopsin.	0.485
LOC103482020	rho	ENSPREP00000031549	ENSPREP00000024057	Retinol binding protein 3.	Rhodopsin; Photoreceptor required for image-forming vision at low light intensity. While most salt water fish species use retinal as chromophore, most freshwater fish use 3-dehydroretinal, or a mixture of retinal and 3-dehydroretinal (By similarity). Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins. Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by arrestin and terminates signaling (By similarity).	0.485
RHO	LOC103482020	ENSPREP00000022363	ENSPREP00000031549	Extra-ocular rhodopsin.	Retinol binding protein 3.	0.485
RHO	Rbp3	ENSPREP00000022363	ENSPREP00000031561	Extra-ocular rhodopsin.	Interphotoreceptor retinoid-binding protein like.	0.485
Rbp3	RHO	ENSPREP00000031561	ENSPREP00000022363	Interphotoreceptor retinoid-binding protein like.	Extra-ocular rhodopsin.	0.485
Rbp3	rho	ENSPREP00000031561	ENSPREP00000024057	Interphotoreceptor retinoid-binding protein like.	Rhodopsin; Photoreceptor required for image-forming vision at low light intensity. While most salt water fish species use retinal as chromophore, most freshwater fish use 3-dehydroretinal, or a mixture of retinal and 3-dehydroretinal (By similarity). Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins. Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by arrestin and terminates signaling (By similarity).	0.485
opn3	LOC103457850	ENSPREP00000004166	ENSPREP00000024988	Opsin 3.	Opsin 8, group member b; Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.	0.470
opn3	opn5	ENSPREP00000004166	ENSPREP00000029640	Opsin 3.	Opsin 5; Belongs to the G-protein coupled receptor 1 family.	0.470