STRINGSTRING
phykpl phykpl gad1 gad1 LOC103460525 LOC103460525 fasn fasn mmachc mmachc sgpl1 sgpl1 LOC103478943 LOC103478943 MOCOS MOCOS hacl1 hacl1 LOC103482020 LOC103482020 Rbp3 Rbp3 LOC103470288 LOC103470288 SHMT2 SHMT2 p4htm p4htm ogfod1 ogfod1 LOC103461928 LOC103461928 LOC103456785 LOC103456785 LOC103456937 LOC103456937 LOC103481891 LOC103481891 phyh phyh p3h2 p3h2 tpk1 tpk1 ogdh ogdh LOC103482421 LOC103482421 ogfod2 ogfod2 scly scly RHO RHO ENSPREP00000022276 ENSPREP00000022276 ENSPREP00000022258 ENSPREP00000022258 got2 got2 mmut mmut LOC103482433 LOC103482433 LOC103463414 LOC103463414 ogfod3 ogfod3 pc pc opn5 opn5 csad csad LOC103480748 LOC103480748 LOC103461994 LOC103461994 GOT1 GOT1 gad2 gad2 TKT TKT tat tat aadat aadat LOC103463413 LOC103463413 LOC103473653 LOC103473653 plod2 plod2 stra6 stra6 LOC103479659 LOC103479659 p4ha1 p4ha1 LOC103481118 LOC103481118 p3h4 p3h4 rbp2 rbp2 LOC103465887 LOC103465887 LOC103465889 LOC103465889 ddc ddc cdcp2 cdcp2 ENSPREP00000017402 ENSPREP00000017402 p3h3 p3h3 slc19a1 slc19a1 crabp1 crabp1 pnpo pnpo LOC103474492 LOC103474492 pam pam LOC103479803 LOC103479803 LOC103479798 LOC103479798 LOC103479320 LOC103479320 LOC103460921 LOC103460921 kyat3 kyat3 LOC103480983 LOC103480983 nfs1 nfs1 slc46a1 slc46a1 kyat1 kyat1 kynu kynu P3H4 P3H4 mmab mmab lmbrd1 lmbrd1 ilvbl ilvbl cubn cubn plpbp plpbp LOC103460663 LOC103460663 crtap crtap cth cth uros uros ism1 ism1 sptlc3 sptlc3 oat oat thnsl2 thnsl2 alas1 alas1 abat abat LOC103465119 LOC103465119 mtarc1 mtarc1 pdxdc1 pdxdc1 gldc gldc egln1 egln1 shmt2 shmt2 p4ha3 p4ha3 plod1 plod1 rbp4 rbp4 mettl26 mettl26 psat1 psat1 pigs pigs HLCS HLCS rho rho LOC103475454 LOC103475454 ENSPREP00000028482 ENSPREP00000028482 LOC103467440 LOC103467440 folr2 folr2 etnppl etnppl p3h1 p3h1 got1 got1 ENSPREP00000029241 ENSPREP00000029241 LOC103469718 LOC103469718 LOC103468004 LOC103468004 LOC103474618 LOC103474618 LOC103462441 LOC103462441 THNSL1 THNSL1 opn3 opn3 egln3 egln3 mtr mtr crabp2 crabp2 LOC103466120 LOC103466120 hdc hdc LOC103467456 LOC103467456 LOC103457821 LOC103457821 ism2 ism2 shmt1 shmt1 ENSPREP00000026406 ENSPREP00000026406 agxt2 agxt2 LOC103478176 LOC103478176 pygl pygl LOC103478736 LOC103478736 LOC103479856 LOC103479856 LOC103457850 LOC103457850 LOC103476575 LOC103476575 CRABP1 CRABP1 sptlc1 sptlc1 p4ha2 p4ha2 ENSPREP00000006057 ENSPREP00000006057 LOC103480109 LOC103480109
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
phykpl5-phosphohydroxy-L-lysine phospho-lyase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (437 aa)
gad1Glutamate decarboxylase 1a. (558 aa)
LOC103460525Serine palmitoyltransferase, long chain base subunit 2a. (565 aa)
fasnCoiled-coil domain containing 57. (2516 aa)
mmachcMetabolism of cobalamin associated C. (274 aa)
sgpl1Sphingosine-1-phosphate lyase 1. (565 aa)
LOC103478943Glutamate decarboxylase 1b. (583 aa)
MOCOSMolybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. (834 aa)
hacl12-hydroxyacyl-CoA lyase 1; Belongs to the TPP enzyme family. (568 aa)
LOC103482020Retinol binding protein 3. (617 aa)
Rbp3Interphotoreceptor retinoid-binding protein like. (910 aa)
LOC103470288Transcobalamin II. (426 aa)
SHMT2Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (530 aa)
p4htmProlyl 4-hydroxylase, transmembrane (endoplasmic reticulum). (497 aa)
ogfod12-oxoglutarate and iron-dependent oxygenase domain containing 1. (459 aa)
LOC103461928Zgc:153901. (329 aa)
LOC103456785Si:dkey-61p9.11. (2009 aa)
LOC103456937Carrier domain-containing protein. (2076 aa)
LOC103481891Prolyl 4-hydroxylase, alpha polypeptide I a. (540 aa)
phyhPhytanoyl-CoA 2-hydroxylase. (333 aa)
p3h2Prolyl 3-hydroxylase 2. (659 aa)
tpk1Thiamine pyrophosphokinase; Belongs to the thiamine pyrophosphokinase family. (294 aa)
ogdhOxoglutarate (alpha-ketoglutarate) dehydrogenase b (lipoamide). (1019 aa)
LOC103482421Complement component 8, gamma polypeptide; Belongs to the calycin superfamily. Lipocalin family. (235 aa)
ogfod22-oxoglutarate and iron-dependent oxygenase domain containing 2. (350 aa)
sclySelenocysteine lyase. (433 aa)
RHOExtra-ocular rhodopsin. (391 aa)
ENSPREP00000022276Uncharacterized protein. (107 aa)
ENSPREP00000022258Glycine C-acetyltransferase. (345 aa)
got2Aspartate aminotransferase. (393 aa)
mmutMethylmalonyl CoA mutase. (464 aa)
LOC103482433Si:ch211-217a12.1. (991 aa)
LOC103463414Aminotran_1_2 domain-containing protein. (460 aa)
ogfod3Urotensin-2 receptor 2. (299 aa)
pcPyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1180 aa)
opn5Opsin 5; Belongs to the G-protein coupled receptor 1 family. (352 aa)
csadCysteine sulfinic acid decarboxylase. (494 aa)
LOC103480748Zgc:101765. (292 aa)
LOC103461994Cytochrome P450, family 27, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family. (538 aa)
GOT1Aspartate aminotransferase. (463 aa)
gad2Glutamate decarboxylase 2. (585 aa)
TKTTransketolase. (629 aa)
tatTyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. (449 aa)
aadatAminoadipate aminotransferase. (437 aa)
LOC103463413Aminotran_1_2 domain-containing protein. (483 aa)
LOC103473653Retinol binding protein 4, like; Belongs to the calycin superfamily. Lipocalin family. (196 aa)
plod2Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2. (756 aa)
stra6Stimulated by retinoic acid 6. (666 aa)
LOC103479659Aminotran_1_2 domain-containing protein. (538 aa)
p4ha1Prolyl 4-hydroxylase, alpha polypeptide I b. (548 aa)
LOC103481118Formimidoyltransferase cyclodeaminase. (539 aa)
p3h4Prolyl 3-hydroxylase family member 4 (non-enzymatic). (428 aa)
rbp2Retinol binding protein 2a, cellular; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (135 aa)
LOC103465887Uncharacterized protein. (487 aa)
LOC103465889Glutamate decarboxylase like 1. (510 aa)
ddcDopa decarboxylase. (474 aa)
cdcp2CUB domain containing protein 2. (390 aa)
ENSPREP00000017402CUB domain-containing protein. (150 aa)
p3h3Prolyl 3-hydroxylase 3. (728 aa)
slc19a1Solute carrier family 19 member 1. (502 aa)
crabp1Cellular retinoic acid binding protein 1a; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (137 aa)
pnpoPyridoxamine 5'-phosphate oxidase. (276 aa)
LOC103474492Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (582 aa)
pamPeptidylglycine alpha-amidating monooxygenase. (947 aa)
LOC103479803Apolipoprotein Da, duplicate 2; Belongs to the calycin superfamily. Lipocalin family. (190 aa)
LOC103479798Apolipoprotein Da, duplicate 2; Belongs to the calycin superfamily. Lipocalin family. (189 aa)
LOC103479320Retinol binding protein 1, cellular, tandem duplicate 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (171 aa)
LOC103460921Pyridoxal (pyridoxine, vitamin B6) kinase a. (314 aa)
kyat3Kynurenine aminotransferase 3. (459 aa)
LOC103480983Lecithin retinol acyltransferase b, tandem duplicate 1. (273 aa)
nfs1NFS1 cysteine desulfurase. (449 aa)
slc46a1Solute carrier family 46 member 1. (492 aa)
kyat1Kynurenine aminotransferase 1. (459 aa)
kynuKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (463 aa)
P3H4Prolyl 3-hydroxylase family member 4 (non-enzymatic). (423 aa)
mmabCorrinoid adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. (230 aa)
lmbrd1LMBR1 domain containing 1. (538 aa)
ilvblIlvB (bacterial acetolactate synthase)-like; Belongs to the TPP enzyme family. (625 aa)
cubnCubilin (intrinsic factor-cobalamin receptor). (3480 aa)
plpbpPyridoxal phosphate homeostasis protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'- phosphate (PLP), the active form of vitamin B6. (298 aa)
LOC103460663AMOP domain-containing protein. (469 aa)
crtapCartilage associated protein. (413 aa)
cthCystathionase (cystathionine gamma-lyase), like. (441 aa)
urosUroporphyrinogen III synthase. (264 aa)
ism1Isthmin 1. (505 aa)
sptlc3Serine palmitoyltransferase, long chain base subunit 3. (548 aa)
oatOrnithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (478 aa)
thnsl2Threonine synthase-like 2. (401 aa)
alas15-aminolevulinate synthase. (623 aa)
abat4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (500 aa)
LOC103465119Transketolase a. (652 aa)
mtarc1Zgc:110783. (329 aa)
pdxdc1Pyridoxal-dependent decarboxylase domain containing 1. (805 aa)
gldcGlycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (1043 aa)
egln1Egl-9 family hypoxia-inducible factor 1a. (360 aa)
shmt2Serine hydroxymethyltransferase 2 (mitochondrial). (515 aa)
p4ha3Prolyl 4-hydroxylase, alpha polypeptide III. (579 aa)
plod1Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1a. (738 aa)
rbp4Retinol binding protein 4, plasma; Belongs to the calycin superfamily. Lipocalin family. (199 aa)
mettl26Methyltransferase like 26. (237 aa)
psat1Phosphoserine aminotransferase. (369 aa)
pigsPhosphatidylinositol glycan anchor biosynthesis, class S. (564 aa)
HLCSHolocarboxylase synthetase. (912 aa)
rhoRhodopsin; Photoreceptor required for image-forming vision at low light intensity. While most salt water fish species use retinal as chromophore, most freshwater fish use 3-dehydroretinal, or a mixture of retinal and 3-dehydroretinal (By similarity). Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins. Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by arrestin and terminates signaling (By similarity). (350 aa)
LOC103475454Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (842 aa)
ENSPREP00000028482Uncharacterized protein. (587 aa)
LOC103467440Transketolase b. (626 aa)
folr2Folate receptor. (242 aa)
etnpplEthanolamine-phosphate phospho-lyase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (460 aa)
p3h1Prolyl 3-hydroxylase 1. (829 aa)
got1Aspartate aminotransferase. (398 aa)
ENSPREP00000029241Preseq_ALAS domain-containing protein. (191 aa)
LOC103469718Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (195 aa)
LOC1034680045-aminolevulinate synthase. (615 aa)
LOC103474618Egl-9 family hypoxia-inducible factor 2. (525 aa)
LOC103462441Cytochrome P450, family 2, subfamily R, polypeptide 1; Belongs to the cytochrome P450 family. (519 aa)
THNSL1Threonine synthase like 1. (723 aa)
opn3Opsin 3. (490 aa)
egln3Egl-9 family hypoxia-inducible factor 3. (266 aa)
mtrMethionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1275 aa)
crabp2Cellular retinoic acid binding protein 2, b; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (142 aa)
LOC1034661201-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional). (969 aa)
hdcHistidine decarboxylase. (670 aa)
LOC103467456Zgc:158254. (505 aa)
LOC103457821Serine palmitoyltransferase, long chain base subunit 2b. (564 aa)
ism2Isthmin 2b. (457 aa)
shmt1Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (442 aa)
ENSPREP00000026406Oxoglutarate dehydrogenase. (353 aa)
agxt2Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (517 aa)
LOC103478176Protein S100; Belongs to the S-100 family. (85 aa)
pyglAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (676 aa)
LOC103478736Cellular retinoic acid binding protein 2, a; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (142 aa)
LOC103479856Glutamic pyruvate transaminase (alanine aminotransferase) 2, like. (542 aa)
LOC103457850Opsin 8, group member b; Belongs to the G-protein coupled receptor 1 family. Opsin subfamily. (345 aa)
LOC103476575Pyridoxal (pyridoxine, vitamin B6) kinase b. (307 aa)
CRABP1Cellular retinoic acid binding protein 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (138 aa)
sptlc1Serine palmitoyltransferase, long chain base subunit 1. (479 aa)
p4ha2Procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide 2. (544 aa)
ENSPREP00000006057Zgc:103625. (197 aa)
LOC103480109Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (842 aa)
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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