(37 nodes) Lipid storage network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103474828	Apolipoprotein A-Ib. (263 aa)
	LOC103474846	Si:ch211-11n16.2. (655 aa)
	LOC103465217	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (159 aa)
	LOC103466557	Beta-hexosaminidase. (532 aa)
	nrip1	Nuclear receptor interacting protein 1b. (1200 aa)
	ENSPREP00000016817	RING-type domain-containing protein. (1774 aa)
	Fitm1	Fat storage inducing transmembrane protein 1. (284 aa)
	Smim22	Uncharacterized protein. (82 aa)
	pnpla2	Patatin-like phospholipase domain containing 2. (489 aa)
	LOC103470686	Interleukin-1. (247 aa)
	LOC103457933	Zinc finger, FYVE domain containing 1. (776 aa)
	ENSPREP00000021082	Ring finger protein 213b. (3184 aa)
	LOC103461074	Uncharacterized protein; Belongs to the CD36 family. (95 aa)
	Gm2a	GM2 ganglioside activator. (198 aa)
	rnf213	Ring finger protein 213a. (4763 aa)
	LOC103479292	Fat storage inducing transmembrane protein 1, like. (284 aa)
	bscl2	Uncharacterized protein. (442 aa)
	sqle	Squalene epoxidase a. (561 aa)
	b4galnt1	Beta-1,4 N-acetylgalactosaminyltransferase. (531 aa)
	LOC103469764	Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin. (462 aa)
	LOC103459750	Patatin-like phospholipase domain containing 3. (473 aa)
	ZFYVE1	Uncharacterized protein. (783 aa)
	LOC103467428	PNPLA domain-containing protein. (435 aa)
	Fitm2	Fat storage inducing transmembrane protein 2. (250 aa)
	LOC103466185	BSCL2 lipid droplet biogenesis associated, seipin. (416 aa)
	angptl3	Angiopoietin-like 3. (466 aa)
	hexb	Beta-hexosaminidase. (546 aa)
	LOC103459298	CD36 molecule (thrombospondin receptor); Belongs to the CD36 family. (409 aa)
	Cav1	Uncharacterized protein. (84 aa)
	LOC103469802	Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin. (457 aa)
	aup1	AUP1 lipid droplet regulating VLDL assembly factor. (415 aa)
	LOC103479015	Fibrinogen C-terminal domain-containing protein. (471 aa)
	ENSPREP00000007552	PNPLA domain-containing protein. (268 aa)
	ldah	Lipid droplet associated hydrolase. (324 aa)
	LOC103477767	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (345 aa)
	ENSPREP00000010266	Uncharacterized protein. (153 aa)
	pla2g4c	Zgc:101699. (580 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000010266	LOC103466185	ENSPREP00000010266	ENSPREP00000030664	Uncharacterized protein.	BSCL2 lipid droplet biogenesis associated, seipin.	0.439
ENSPREP00000010266	bscl2	ENSPREP00000010266	ENSPREP00000022757	Uncharacterized protein.	Uncharacterized protein.	0.439
Fitm2	sqle	ENSPREP00000030442	ENSPREP00000024231	Fat storage inducing transmembrane protein 2.	Squalene epoxidase a.	0.547
Gm2a	LOC103466557	ENSPREP00000022022	ENSPREP00000014928	GM2 ganglioside activator.	Beta-hexosaminidase.	0.727
Gm2a	hexb	ENSPREP00000022022	ENSPREP00000031004	GM2 ganglioside activator.	Beta-hexosaminidase.	0.727
LOC103457933	LOC103474846	ENSPREP00000019985	ENSPREP00000011748	Zinc finger, FYVE domain containing 1.	Si:ch211-11n16.2.	0.902
LOC103457933	ZFYVE1	ENSPREP00000019985	ENSPREP00000028864	Zinc finger, FYVE domain containing 1.	Uncharacterized protein.	0.901
LOC103459298	LOC103461074	ENSPREP00000032895	ENSPREP00000021312	CD36 molecule (thrombospondin receptor); Belongs to the CD36 family.	Uncharacterized protein; Belongs to the CD36 family.	0.920
LOC103459298	LOC103474828	ENSPREP00000032895	ENSPREP00000010904	CD36 molecule (thrombospondin receptor); Belongs to the CD36 family.	Apolipoprotein A-Ib.	0.558
LOC103459750	LOC103467428	ENSPREP00000026453	ENSPREP00000029147	Patatin-like phospholipase domain containing 3.	PNPLA domain-containing protein.	0.909
LOC103459750	pnpla2	ENSPREP00000026453	ENSPREP00000017479	Patatin-like phospholipase domain containing 3.	Patatin-like phospholipase domain containing 2.	0.903
LOC103461074	LOC103459298	ENSPREP00000021312	ENSPREP00000032895	Uncharacterized protein; Belongs to the CD36 family.	CD36 molecule (thrombospondin receptor); Belongs to the CD36 family.	0.920
LOC103461074	LOC103474828	ENSPREP00000021312	ENSPREP00000010904	Uncharacterized protein; Belongs to the CD36 family.	Apolipoprotein A-Ib.	0.558
LOC103466185	ENSPREP00000010266	ENSPREP00000030664	ENSPREP00000010266	BSCL2 lipid droplet biogenesis associated, seipin.	Uncharacterized protein.	0.439
LOC103466557	Gm2a	ENSPREP00000014928	ENSPREP00000022022	Beta-hexosaminidase.	GM2 ganglioside activator.	0.727
LOC103466557	b4galnt1	ENSPREP00000014928	ENSPREP00000025203	Beta-hexosaminidase.	Beta-1,4 N-acetylgalactosaminyltransferase.	0.920
LOC103467428	LOC103459750	ENSPREP00000029147	ENSPREP00000026453	PNPLA domain-containing protein.	Patatin-like phospholipase domain containing 3.	0.909
LOC103467428	pnpla2	ENSPREP00000029147	ENSPREP00000017479	PNPLA domain-containing protein.	Patatin-like phospholipase domain containing 2.	0.909
LOC103469764	LOC103469802	ENSPREP00000025945	ENSPREP00000004237	Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin.	Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin.	0.901
LOC103469764	aup1	ENSPREP00000025945	ENSPREP00000005809	Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin.	AUP1 lipid droplet regulating VLDL assembly factor.	0.402