(16 nodes) Cell proliferation in forebrain network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	fgf16	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (190 aa)
	Six3	SIX homeobox 3a. (341 aa)
	LOC103475931	SIX homeobox 7. (260 aa)
	pcm1	Pericentriolar material 1. (2112 aa)
	LOC103465913	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
	LOC103467575	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (364 aa)
	wnt7b	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
	numb	NUMB endocytic adaptor protein. (661 aa)
	ENSPREP00000012400	Uncharacterized protein. (550 aa)
	LOC103474847	NUMB like endocytic adaptor protein. (751 aa)
	ENSPREP00000011364	Kinesin family member 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1074 aa)
	LOC103481539	SIX homeobox 3b. (277 aa)
	six6	SIX homeobox 6a. (245 aa)
	ENSPREP00000027668	Centrosomal protein 120. (452 aa)
	Cep120	DUF3668 domain-containing protein. (223 aa)
	WNT7A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (396 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cep120	ENSPREP00000027668	ENSPREP00000027686	ENSPREP00000027668	DUF3668 domain-containing protein.	Centrosomal protein 120.	0.926
ENSPREP00000012400	pcm1	ENSPREP00000012400	ENSPREP00000000099	Uncharacterized protein.	Pericentriolar material 1.	0.488
ENSPREP00000027668	Cep120	ENSPREP00000027668	ENSPREP00000027686	Centrosomal protein 120.	DUF3668 domain-containing protein.	0.926
LOC103474847	numb	ENSPREP00000011797	ENSPREP00000012443	NUMB like endocytic adaptor protein.	NUMB endocytic adaptor protein.	0.903
numb	LOC103474847	ENSPREP00000012443	ENSPREP00000011797	NUMB endocytic adaptor protein.	NUMB like endocytic adaptor protein.	0.903
pcm1	ENSPREP00000012400	ENSPREP00000000099	ENSPREP00000012400	Pericentriolar material 1.	Uncharacterized protein.	0.488