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sdhd sdhd ND2 ND2 COX3 COX3 ND4L ND4L ND4 ND4 ND5 ND5 CYTB CYTB UQCRFS1 UQCRFS1 LOC103479501 LOC103479501 ndufs2 ndufs2 LOC103477149 LOC103477149 ndufb8 ndufb8 LOC103468045 LOC103468045 LOC103462283 LOC103462283 taz taz coq9 coq9 pm20d1 pm20d1 LOC103470443 LOC103470443 SLC25A12 SLC25A12 ENSPREP00000006375 ENSPREP00000006375 ENSPREP00000007383 ENSPREP00000007383 LOC103465156 LOC103465156 LOC103471204 LOC103471204 ndufb6 ndufb6 NDUFS1 NDUFS1 LOC103460043 LOC103460043 ENSPREP00000009873 ENSPREP00000009873 ENSPREP00000010030 ENSPREP00000010030 LOC103478105 LOC103478105 LOC103472391 LOC103472391 etfdh etfdh etfa etfa COX5A COX5A ENSPREP00000012395 ENSPREP00000012395 ndufa7 ndufa7 ndufa8 ndufa8 SDHB SDHB ndufv2 ndufv2 LOC103463587 LOC103463587 ndufs7 ndufs7 LOC108165850 LOC108165850 LOC103475208 LOC103475208 slc25a22 slc25a22 LOC103464689 LOC103464689 LOC103470667 LOC103470667 ndufa5 ndufa5 LOC103462885 LOC103462885 LOC103472506 LOC103472506 aifm2 aifm2 COX5B COX5B LOC103473152 LOC103473152 LOC103473754 LOC103473754 LOC103457043 LOC103457043 sdha sdha LOC103479323 LOC103479323 LOC103475017 LOC103475017 LOC103459661 LOC103459661 ENSPREP00000022990 ENSPREP00000022990 ndufv3 ndufv3 ndufa10 ndufa10 LOC103460371 LOC103460371 LOC103466419 LOC103466419 sdhaf2 sdhaf2 ndufa12 ndufa12 pink1 pink1 NDUFS8 NDUFS8 ENSPREP00000032047 ENSPREP00000032047 ndufb9 ndufb9 slc25a18 slc25a18 LOC103466780 LOC103466780 ENSPREP00000029837 ENSPREP00000029837 ppargc1a ppargc1a polg2 polg2 ndufaf1 ndufaf1 LOC103479449 LOC103479449 LOC108166662 LOC108166662 ndufs6 ndufs6 clg21h1orf198 clg21h1orf198
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
sdhdSuccinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (166 aa)
ND2NADH-ubiquinone oxidoreductase chain 2; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (348 aa)
COX3Cytochrome c oxidase subunit 3; Subunits I, II and III form the functional core of the enzyme complex. (261 aa)
ND4LNADH-ubiquinone oxidoreductase chain 4L; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (98 aa)
ND4NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (460 aa)
ND5NADH-ubiquinone oxidoreductase chain 5; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (612 aa)
CYTBCytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis. (379 aa)
UQCRFS1Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (264 aa)
LOC103479501Succinate dehydrogenase complex, subunit C, integral membrane protein. (153 aa)
ndufs2NADH:ubiquinone oxidoreductase core subunit S2; Belongs to the complex I 49 kDa subunit family. (467 aa)
LOC103477149Cytochrome c oxidase subunit 5B2. (212 aa)
ndufb8NADH:ubiquinone oxidoreductase subunit B8. (202 aa)
LOC103468045Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (398 aa)
LOC103462283Ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1. (286 aa)
tazTafazzin family protein; Belongs to the taffazin family. (187 aa)
coq9Ubiquinone biosynthesis protein; Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. (339 aa)
pm20d1Peptidase M20 domain containing 1, tandem duplicate 2. (520 aa)
LOC103470443Cytochrome c oxidase subunit 7C. (63 aa)
SLC25A12Solute carrier family 25 member 12; Belongs to the mitochondrial carrier (TC 2.A.29) family. (673 aa)
ENSPREP00000006375Cytochrome c oxidase subunit 4I2. (178 aa)
ENSPREP00000007383Cytochrome c oxidase subunit 7A2 like. (157 aa)
LOC103465156Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (290 aa)
LOC103471204Ubiquinol-cytochrome c reductase, complex III subunit VII. (82 aa)
ndufb6NADH:ubiquinone oxidoreductase subunit B. (127 aa)
NDUFS1NADH:ubiquinone oxidoreductase core subunit S1. (677 aa)
LOC103460043Cytochrome c oxidase subunit 7A1. (81 aa)
ENSPREP00000009873Uncharacterized protein. (66 aa)
ENSPREP00000010030Electron transfer flavoprotein subunit beta. (243 aa)
LOC103478105NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (455 aa)
LOC103472391Cytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain; Belongs to the UQCRB/QCR7 family. (110 aa)
etfdhElectron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (622 aa)
etfaElectron transfer flavoprotein subunit alpha. (347 aa)
COX5ACytochrome c oxidase subunit 5Ab. (184 aa)
ENSPREP00000012395UCR_hinge domain-containing protein. (111 aa)
ndufa7NADH:ubiquinone oxidoreductase subunit A7. (113 aa)
ndufa8NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (172 aa)
SDHBSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (339 aa)
ndufv2NADH:ubiquinone oxidoreductase core subunit V2. (230 aa)
LOC103463587Ubiquinol-cytochrome c reductase hinge protein. (88 aa)
ndufs7NADH:ubiquinone oxidoreductase core subunit S7; Belongs to the complex I 20 kDa subunit family. (199 aa)
LOC108165850Uncharacterized protein. (70 aa)
LOC103475208NADH:ubiquinone oxidoreductase core subunit S1; Belongs to the complex I 75 kDa subunit family. (770 aa)
slc25a22Solute carrier family 25 member 22a; Belongs to the mitochondrial carrier (TC 2.A.29) family. (312 aa)
LOC103464689Solute carrier family 25 member 55a; Belongs to the mitochondrial carrier (TC 2.A.29) family. (326 aa)
LOC103470667Uncharacterized protein. (81 aa)
ndufa5NADH:ubiquinone oxidoreductase subunit A5. (101 aa)
LOC103462885Cytochrome c oxidase subunit 4I1. (169 aa)
LOC103472506NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (464 aa)
aifm2Apoptosis inducing factor mitochondria associated 2. (360 aa)
COX5BCytochrome c oxidase subunit 5B. (153 aa)
LOC103473152Uncharacterized protein. (126 aa)
LOC103473754Ubiquinol-cytochrome c reductase, complex III subunit X. (61 aa)
LOC103457043Cytochrome c oxidase subunit 7A2. (84 aa)
sdhaSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (663 aa)
LOC103479323Solute carrier family 25 member 12; Belongs to the mitochondrial carrier (TC 2.A.29) family. (683 aa)
LOC103475017NADH dehydrogenase [ubiquinone] 1 subunit C2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (110 aa)
LOC103459661Cytochrome c oxidase assembly factor 6. (81 aa)
ENSPREP00000022990LYR motif containing 5a; Belongs to the complex I LYR family. (78 aa)
ndufv3Uncharacterized protein. (487 aa)
ndufa10NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (355 aa)
LOC103460371Cytochrome c-1. (307 aa)
LOC103466419Uncharacterized protein. (141 aa)
sdhaf2Succinate dehydrogenase assembly factor 2, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer. (150 aa)
ndufa12NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (150 aa)
pink1PTEN induced kinase 1. (575 aa)
NDUFS8NADH:ubiquinone oxidoreductase core subunit S8. (221 aa)
ENSPREP00000032047dNK domain-containing protein. (187 aa)
ndufb9NADH:ubiquinone oxidoreductase subunit B9; Belongs to the complex I LYR family. (175 aa)
slc25a18Solute carrier family 25 member 18; Belongs to the mitochondrial carrier (TC 2.A.29) family. (313 aa)
LOC103466780LYR motif containing 5b; Belongs to the complex I LYR family. (89 aa)
ENSPREP00000029837Uncharacterized protein. (88 aa)
ppargc1aPeroxisome proliferator-activated receptor gamma, coactivator 1 alpha. (1284 aa)
polg2Polymerase (DNA directed), gamma 2, accessory subunit. (446 aa)
ndufaf1NADH:ubiquinone oxidoreductase complex assembly factor 1. (314 aa)
LOC103479449Uncharacterized protein. (56 aa)
LOC108166662Uncharacterized protein. (191 aa)
ndufs6NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (130 aa)
clg21h1orf198Si:ch73-111k22.2. (353 aa)
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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