(15 nodes) Natural killer cell activation network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	hectd1	HECT domain containing 1. (2572 aa)
	LOC103464509	Tumor suppressor 2, mitochondrial calcium regulator. (109 aa)
	SP3	Sp3a transcription factor. (699 aa)
	LOC103458727	Sp3b transcription factor. (680 aa)
	ENSPREP00000014219	Ig-like domain-containing protein. (320 aa)
	ENSPREP00000016463	Uncharacterized protein. (111 aa)
	LOC103474923	Ig-like domain-containing protein. (317 aa)
	LOC108166835	Ig-like domain-containing protein. (314 aa)
	cd2	Ig-like domain-containing protein. (377 aa)
	ptprc	Protein tyrosine phosphatase receptor type C. (1230 aa)
	rabl3	RAB, member of RAS oncogene family-like 3. (233 aa)
	IL18	Uncharacterized protein. (218 aa)
	AXL	AXL receptor tyrosine kinase. (885 aa)
	LOC103468486	IL2RB_N1 domain-containing protein. (545 aa)
	mertk	C-mer proto-oncogene tyrosine kinase a. (943 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000014219	LOC103468486	ENSPREP00000014219	ENSPREP00000027487	Ig-like domain-containing protein.	IL2RB_N1 domain-containing protein.	0.438
ENSPREP00000014219	LOC108166835	ENSPREP00000014219	ENSPREP00000018050	Ig-like domain-containing protein.	Ig-like domain-containing protein.	0.900
ENSPREP00000014219	cd2	ENSPREP00000014219	ENSPREP00000018056	Ig-like domain-containing protein.	Ig-like domain-containing protein.	0.900
ENSPREP00000014219	ptprc	ENSPREP00000014219	ENSPREP00000018309	Ig-like domain-containing protein.	Protein tyrosine phosphatase receptor type C.	0.447
LOC103468486	ENSPREP00000014219	ENSPREP00000027487	ENSPREP00000014219	IL2RB_N1 domain-containing protein.	Ig-like domain-containing protein.	0.438
LOC103468486	LOC103474923	ENSPREP00000027487	ENSPREP00000018013	IL2RB_N1 domain-containing protein.	Ig-like domain-containing protein.	0.438
LOC103468486	LOC108166835	ENSPREP00000027487	ENSPREP00000018050	IL2RB_N1 domain-containing protein.	Ig-like domain-containing protein.	0.438
LOC103468486	cd2	ENSPREP00000027487	ENSPREP00000018056	IL2RB_N1 domain-containing protein.	Ig-like domain-containing protein.	0.553
LOC103468486	ptprc	ENSPREP00000027487	ENSPREP00000018309	IL2RB_N1 domain-containing protein.	Protein tyrosine phosphatase receptor type C.	0.498
LOC103474923	LOC103468486	ENSPREP00000018013	ENSPREP00000027487	Ig-like domain-containing protein.	IL2RB_N1 domain-containing protein.	0.438
LOC103474923	ptprc	ENSPREP00000018013	ENSPREP00000018309	Ig-like domain-containing protein.	Protein tyrosine phosphatase receptor type C.	0.447
LOC108166835	ENSPREP00000014219	ENSPREP00000018050	ENSPREP00000014219	Ig-like domain-containing protein.	Ig-like domain-containing protein.	0.900
LOC108166835	LOC103468486	ENSPREP00000018050	ENSPREP00000027487	Ig-like domain-containing protein.	IL2RB_N1 domain-containing protein.	0.438
LOC108166835	cd2	ENSPREP00000018050	ENSPREP00000018056	Ig-like domain-containing protein.	Ig-like domain-containing protein.	0.902
LOC108166835	ptprc	ENSPREP00000018050	ENSPREP00000018309	Ig-like domain-containing protein.	Protein tyrosine phosphatase receptor type C.	0.447
cd2	ENSPREP00000014219	ENSPREP00000018056	ENSPREP00000014219	Ig-like domain-containing protein.	Ig-like domain-containing protein.	0.900
cd2	LOC103468486	ENSPREP00000018056	ENSPREP00000027487	Ig-like domain-containing protein.	IL2RB_N1 domain-containing protein.	0.553
cd2	LOC108166835	ENSPREP00000018056	ENSPREP00000018050	Ig-like domain-containing protein.	Ig-like domain-containing protein.	0.902
cd2	ptprc	ENSPREP00000018056	ENSPREP00000018309	Ig-like domain-containing protein.	Protein tyrosine phosphatase receptor type C.	0.447
ptprc	ENSPREP00000014219	ENSPREP00000018309	ENSPREP00000014219	Protein tyrosine phosphatase receptor type C.	Ig-like domain-containing protein.	0.447