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clta clta LOC103467039 LOC103467039 LOC103472859 LOC103472859 ENSPREP00000000770 ENSPREP00000000770 gopc gopc snx9 snx9 vti1a vti1a LOC103457562 LOC103457562 LOC103481437 LOC103481437 scyl2 scyl2 ENSPREP00000002434 ENSPREP00000002434 atp6ap1 atp6ap1 ENSPREP00000002746 ENSPREP00000002746 spg21 spg21 dct dct inpp5f inpp5f LOC103462258 LOC103462258 LOC103464892 LOC103464892 ENSPREP00000004746 ENSPREP00000004746 LOC103474743 LOC103474743 LOC103468803 LOC103468803 LOC103478999 LOC103478999 LOC103471986 LOC103471986 necap2 necap2 LOC103460653 LOC103460653 LOC103471122 LOC103471122 LOC103468143 LOC103468143 vps41 vps41 atp6v1f atp6v1f LOC103475391 LOC103475391 aak1 aak1 atp6ap2 atp6ap2 ENSPREP00000011525 ENSPREP00000011525 LOC103475657 LOC103475657 vps33a vps33a atp6v1d atp6v1d fcho1 fcho1 cltc cltc epn1 epn1 LOC103478044 LOC103478044 synrg synrg LOC103480389 LOC103480389 sgip1 sgip1 LOC103465226 LOC103465226 clvs1 clvs1 LOC103468936 LOC103468936 LOC103481184 LOC103481184 LOC103481050 LOC103481050 vps16 vps16 LOC103458439 LOC103458439 LOC103469120 LOC103469120 cltcl1 cltcl1 LOC103473710 LOC103473710 picalm picalm LOC103457075 LOC103457075 dennd1a dennd1a LOC103457710 LOC103457710 AP3B2 AP3B2 vps11 vps11 ap2m1 ap2m1 LOC103463979 LOC103463979 pheta1 pheta1 ENSPREP00000021351 ENSPREP00000021351 LOC103466445 LOC103466445 LOC103469107 LOC103469107 snap91 snap91 rab35 rab35 LOC103482389 LOC103482389 epn2 epn2 atp6v1h atp6v1h atp6v0b atp6v0b LOC103476383 LOC103476383 rab13 rab13 LOC103473248 LOC103473248 ENSPREP00000026258 ENSPREP00000026258 igf2r igf2r tyrp1 tyrp1 clvs2 clvs2 hip1 hip1 LOC103481105 LOC103481105 atp6v1a atp6v1a ap3b1 ap3b1 clint1 clint1 hax1 hax1 ENSPREP00000030224 ENSPREP00000030224 LOC103475419 LOC103475419 adcy8 adcy8 fcho2 fcho2 LOC103467860 LOC103467860 astn1 astn1 LOC103470262 LOC103470262 MYO6 MYO6 ENSPREP00000031713 ENSPREP00000031713 LOC103457333 LOC103457333 LOC103475259 LOC103475259 ap1b1 ap1b1 LOC103478890 LOC103478890 NRGN NRGN lmbrd1 lmbrd1 ap2s1 ap2s1 ENSPREP00000034049 ENSPREP00000034049 ENSPREP00000034066 ENSPREP00000034066 ap1g1 ap1g1 adam10 adam10
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cltaClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (220 aa)
LOC103467039Epsin 3b. (615 aa)
LOC103472859NECAP endocytosis associated 1. (278 aa)
ENSPREP00000000770ENTH domain-containing protein. (104 aa)
gopcGolgi-associated PDZ and coiled-coil motif containing. (445 aa)
snx9Sorting nexin 9b. (630 aa)
vti1aVesicle transport through interaction with t-SNAREs 1A. (224 aa)
LOC103457562Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1185 aa)
LOC103481437Solute carrier family 18 member A3. (518 aa)
scyl2SCY1 like pseudokinase 2. (914 aa)
ENSPREP00000002434Uncharacterized protein. (135 aa)
atp6ap1ATPase H+ transporting accessory protein 1a. (489 aa)
ENSPREP00000002746Sortilin. (632 aa)
spg21SPG21 abhydrolase domain containing, maspardin. (311 aa)
dctDopachrome tautomerase. (528 aa)
inpp5fInositol polyphosphate-5-phosphatase F. (1159 aa)
LOC103462258AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (956 aa)
LOC103464892Sortilin. (808 aa)
ENSPREP00000004746V-SNARE coiled-coil homology domain-containing protein. (94 aa)
LOC103474743Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1685 aa)
LOC103468803Epsin 3a. (602 aa)
LOC103478999MHD domain-containing protein. (895 aa)
LOC103471986Aftiphilin a. (697 aa)
necap2NECAP endocytosis associated 2. (253 aa)
LOC103460653Si:dkey-16l2.16. (209 aa)
LOC103471122Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (200 aa)
LOC103468143AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (938 aa)
vps41Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family. (846 aa)
atp6v1fV-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (119 aa)
LOC103475391ENTH domain-containing protein. (593 aa)
aak1AP2 associated kinase 1a. (1055 aa)
atp6ap2ATPase H+ transporting accessory protein 2. (381 aa)
ENSPREP00000011525Uncharacterized protein. (185 aa)
LOC103475657ENTH domain-containing protein. (630 aa)
vps33aVPS33A core subunit of CORVET and HOPS complexes; Belongs to the STXBP/unc-18/SEC1 family. (600 aa)
atp6v1dATPase H+ transporting V1 subunit D. (248 aa)
fcho1FCH domain only 1. (1193 aa)
cltcClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1700 aa)
epn1Epsin 1. (622 aa)
LOC103478044DUF1681 domain-containing protein. (252 aa)
synrgSynergin, gamma. (1434 aa)
LOC103480389Si:ch211-200p22.4. (642 aa)
sgip1SH3-domain GRB2-like (endophilin) interacting protein 1a. (938 aa)
LOC103465226ER membrane protein complex subunit 3; Belongs to the EMC3 family. (261 aa)
clvs1CRAL-TRIO domain-containing protein. (327 aa)
LOC103468936Zgc:153733. (261 aa)
LOC103481184Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1181 aa)
LOC103481050Uncharacterized protein. (530 aa)
vps16Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family. (834 aa)
LOC103458439Receptor expression-enhancing protein. (184 aa)
LOC103469120Tyrosinase-related protein 1b. (549 aa)
cltcl1Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1696 aa)
LOC103473710AP2 associated kinase 1b. (1079 aa)
picalmPhosphatidylinositol binding clathrin assembly protein b. (588 aa)
LOC103457075Myosin VIa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (955 aa)
dennd1aDENN/MADD domain containing 1A. (996 aa)
LOC103457710Synaptosome associated protein 91b. (720 aa)
AP3B2AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (988 aa)
vps11Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family. (928 aa)
ap2m1AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (358 aa)
LOC103463979Si:ch73-389b16.2. (1535 aa)
pheta1Si:ch211-193c2.2. (269 aa)
ENSPREP00000021351Uncharacterized protein. (159 aa)
LOC103466445ADAM metallopeptidase domain 10b. (781 aa)
LOC103469107V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (154 aa)
snap91Synaptosome associated protein 91a. (969 aa)
rab35RAB35, member RAS oncogene family b. (184 aa)
LOC103482389SH3-domain binding protein 4. (962 aa)
epn2Epsin 2. (532 aa)
atp6v1hV-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (451 aa)
atp6v0bATPase H+ transporting V0 subunit b; Belongs to the V-ATPase proteolipid subunit family. (211 aa)
LOC103476383AP complex subunit beta. (953 aa)
rab13RAB13, member RAS oncogene family. (216 aa)
LOC103473248I/LWEQ domain-containing protein. (991 aa)
ENSPREP00000026258Solute carrier family 18 member 3a. (511 aa)
igf2rInsulin-like growth factor 2 receptor. (1923 aa)
tyrp1Tyrosinase related protein 1. (525 aa)
clvs2Clavesin 2. (333 aa)
hip1Huntingtin interacting protein 1. (1050 aa)
LOC103481105V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (153 aa)
atp6v1aATPase H+ transporting V1 subunit A. (617 aa)
ap3b1AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1103 aa)
clint1Clathrin interactor 1a. (617 aa)
hax1HCLS1 associated protein X-1. (288 aa)
ENSPREP00000030224PID domain-containing protein. (124 aa)
LOC103475419Uncharacterized protein. (617 aa)
adcy8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1239 aa)
fcho2FCH domain only 2. (763 aa)
LOC103467860ATPase H+ transporting accessory protein 1b. (446 aa)
astn1Astrotactin 1. (1066 aa)
LOC103470262Huntingtin interacting protein 1 related b. (1028 aa)
MYO6Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1214 aa)
ENSPREP00000031713Uncharacterized protein. (157 aa)
LOC103457333SH3-domain binding protein 4a. (960 aa)
LOC103475259Clarin 1. (200 aa)
ap1b1AP complex subunit beta. (1003 aa)
LOC103478890AP-1 complex subunit gamma. (794 aa)
NRGNNeurogranin. (90 aa)
lmbrd1LMBR1 domain containing 1. (538 aa)
ap2s1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (141 aa)
ENSPREP00000034049PH domain-containing protein. (266 aa)
ENSPREP00000034066Stonin-1; May be involved in the endocytic machinery. (659 aa)
ap1g1AP-1 complex subunit gamma. (785 aa)
adam10Uncharacterized protein. (645 aa)
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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