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vps9d1 vps9d1 sh3kbp1 sh3kbp1 LOC103462425 LOC103462425 ap2s1 ap2s1 rab20 rab20 lmbrd1 lmbrd1 stxbp3 stxbp3 rab23 rab23 LOC103481258 LOC103481258 vamp7 vamp7 LOC103457268 LOC103457268 lamp1 lamp1 MYO6 MYO6 LOC103470250 LOC103470250 LOC103475233 LOC103475233 ambra1 ambra1 RAB38 RAB38 LOC103476509 LOC103476509 LOC103481860 LOC103481860 ENSPREP00000029685 ENSPREP00000029685 pip4p1 pip4p1 ENSPREP00000029452 ENSPREP00000029452 LOC103458514 LOC103458514 LOC103477637 LOC103477637 appl2 appl2 RAB11FIP3 RAB11FIP3 tyrp1 tyrp1 igf2r igf2r LOC103465062 LOC103465062 ENSPREP00000026258 ENSPREP00000026258 LOC103474429 LOC103474429 rab13 rab13 LOC103470772 LOC103470772 LOC103477555 LOC103477555 Mib1 Mib1 pikfyve pikfyve stx8 stx8 LOC103480619 LOC103480619 EHD2 EHD2 LOC103473229 LOC103473229 rab10 rab10 LOC103471421 LOC103471421 stxbp4 stxbp4 rab35 rab35 ENSPREP00000022805 ENSPREP00000022805 ENSPREP00000022754 ENSPREP00000022754 ENSPREP00000022524 ENSPREP00000022524 rabep1 rabep1 LOC103473793 LOC103473793 LOC103479314 LOC103479314 ap2m1 ap2m1 vps11 vps11 stx7 stx7 rab11fip4 rab11fip4 LOC103475527 LOC103475527 LOC103457740 LOC103457740 rab8a rab8a ENSPREP00000018481 ENSPREP00000018481 ENSPREP00000018072 ENSPREP00000018072 RAB7A RAB7A LOC103479775 LOC103479775 lamp2 lamp2 ocrl ocrl LOC103457075 LOC103457075 LOC103466506 LOC103466506 ecpas ecpas gapvd1 gapvd1 Mtor Mtor ENSPREP00000016383 ENSPREP00000016383 ENSPREP00000016378 ENSPREP00000016378 cltcl1 cltcl1 LOC103469120 LOC103469120 rab22a rab22a nod1 nod1 zyx zyx LOC103457353 LOC103457353 RAB31 RAB31 rab5c rab5c uvrag uvrag cdc42ep4 cdc42ep4 LOC103480138 LOC103480138 LOC103473662 LOC103473662 LOC103460107 LOC103460107 LOC103480388 LOC103480388 rab8b rab8b cltc cltc LOC103474865 LOC103474865 LOC103460086 LOC103460086 tlr2 tlr2 scarb2 scarb2 heatr5b heatr5b pip4p2 pip4p2 rapgef2 rapgef2 LOC103474828 LOC103474828 LOC103475390 LOC103475390 LOC103468194 LOC103468194 flot2 flot2 ENSPREP00000010233 ENSPREP00000010233 nod2 nod2 ENSPREP00000009603 ENSPREP00000009603 LOC103463719 LOC103463719 LOC103463721 LOC103463721 LOC103468143 LOC103468143 RABGEF1 RABGEF1 LOC103480941 LOC103480941 stx6 stx6 sh3d21 sh3d21 LOC103460673 LOC103460673 Lpar2 Lpar2 inpp5b inpp5b LOC103460653 LOC103460653 tirap tirap LOC103477863 LOC103477863 LOC103474743 LOC103474743 pik3c3 pik3c3 srgap2 srgap2 LOC103468815 LOC103468815 rapgef6 rapgef6 LOC103458107 LOC103458107 ENSPREP00000004746 ENSPREP00000004746 ENSPREP00000004733 ENSPREP00000004733 rin1 rin1 stam2 stam2 amn amn LOC103462258 LOC103462258 RIN2 RIN2 rab32 rab32 inpp5f inpp5f atg14 atg14 dct dct LOC103471313 LOC103471313 CD2AP CD2AP RAB9A RAB9A ENSPREP00000002434 ENSPREP00000002434 LOC103474679 LOC103474679 unc93b1 unc93b1 LOC103481437 LOC103481437 appl1 appl1 lpar1 lpar1 stx10 stx10 ENSPREP00000000256 ENSPREP00000000256
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
vps9d1VPS9 domain containing 1. (675 aa)
sh3kbp1SH3-domain kinase binding protein 1. (605 aa)
LOC103462425Synaptotagmin VIIb. (468 aa)
ap2s1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (141 aa)
rab20RAB20, member RAS oncogene family. (263 aa)
lmbrd1LMBR1 domain containing 1. (538 aa)
stxbp3Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (592 aa)
rab23RAB23, member RAS oncogene family. (204 aa)
LOC103481258Uncharacterized protein. (228 aa)
vamp7Synaptobrevin-like 1; Belongs to the synaptobrevin family. (220 aa)
LOC103457268Si:ch211-108d22.2. (2793 aa)
lamp1Lysosomal associated membrane protein 1a. (409 aa)
MYO6Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1214 aa)
LOC103470250Uncharacterized protein. (460 aa)
LOC103475233Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (428 aa)
ambra1Autophagy/beclin-1 regulator 1b. (1210 aa)
RAB38RAB38, member RAS oncogene family. (212 aa)
LOC103476509Ras and Rab interactor 2. (944 aa)
LOC103481860RAB5B, member RAS oncogene family. (216 aa)
ENSPREP00000029685Syntaxin 12. (256 aa)
pip4p1Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (260 aa)
ENSPREP00000029452Uncharacterized protein. (102 aa)
LOC103458514RAB15, member RAS oncogene family. (210 aa)
LOC103477637Toll-like receptor 18. (882 aa)
appl2Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2. (710 aa)
RAB11FIP3RAB11 family interacting protein 3. (414 aa)
tyrp1Tyrosinase related protein 1. (525 aa)
igf2rInsulin-like growth factor 2 receptor. (1923 aa)
LOC103465062RAB7a, member RAS oncogene family. (207 aa)
ENSPREP00000026258Solute carrier family 18 member 3a. (511 aa)
LOC103474429EH-domain containing 2a; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (545 aa)
rab13RAB13, member RAS oncogene family. (216 aa)
LOC103470772Uncharacterized protein. (216 aa)
LOC103477555RAB11a, member RAS oncogene family, like. (216 aa)
Mib1Mindbomb E3 ubiquitin protein ligase 1. (994 aa)
pikfyvePhosphoinositide kinase, FYVE finger containing. (2073 aa)
stx8Syntaxin 8. (332 aa)
LOC103480619Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (322 aa)
EHD2EH-domain containing 2b; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (540 aa)
LOC103473229Occludin a. (496 aa)
rab10RAB10, member RAS oncogene family. (225 aa)
LOC103471421EH-domain containing 1a; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (533 aa)
stxbp4Syntaxin binding protein 4. (705 aa)
rab35RAB35, member RAS oncogene family b. (184 aa)
ENSPREP00000022805V-SNARE coiled-coil homology domain-containing protein. (116 aa)
ENSPREP00000022754Vesicle-associated membrane protein 8 (endobrevin). (118 aa)
ENSPREP00000022524Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (174 aa)
rabep1Rabaptin, RAB GTPase binding effector protein 1. (890 aa)
LOC103473793RAB14, member RAS oncogene family. (197 aa)
LOC103479314Uncharacterized protein. (220 aa)
ap2m1AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (358 aa)
vps11Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family. (928 aa)
stx7Syntaxin 7-like; Belongs to the syntaxin family. (255 aa)
rab11fip4RAB11 family interacting protein 4 (class II) b. (514 aa)
LOC103475527RAB38b, member of RAS oncogene family. (218 aa)
LOC103457740EH-domain containing 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (535 aa)
rab8aRAB8A, member RAS oncogene family. (206 aa)
ENSPREP00000018481Uncharacterized protein. (201 aa)
ENSPREP00000018072Uncharacterized protein. (672 aa)
RAB7ARAB7A, member RAS oncogene family. (207 aa)
LOC103479775RAB8A, member RAS oncogene family. (234 aa)
lamp2Lysosomal-associated membrane protein 2. (411 aa)
ocrlOCRL inositol polyphosphate-5-phosphatase. (874 aa)
LOC103457075Myosin VIa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (955 aa)
LOC103466506Synaptotagmin VIIa. (606 aa)
ecpasEcm29 proteasome adaptor and scaffold. (1869 aa)
gapvd1GTPase activating protein and VPS9 domains 1. (1493 aa)
MtorSerine/threonine-protein kinase TOR. (1001 aa)
ENSPREP00000016383ADP-ribosylation factor 6b. (113 aa)
ENSPREP00000016378Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family. (702 aa)
cltcl1Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1696 aa)
LOC103469120Tyrosinase-related protein 1b. (549 aa)
rab22aRAB22A, member RAS oncogene family. (194 aa)
nod1Nucleotide-binding oligomerization domain containing 1. (884 aa)
zyxZyxin. (556 aa)
LOC103457353RAB15, member RAS oncogene family. (213 aa)
RAB31RAB31, member RAS oncogene family. (195 aa)
rab5cRAB5C, member RAS oncogene family. (220 aa)
uvragUV radiation resistance associated gene. (743 aa)
cdc42ep4CDC42 effector protein (Rho GTPase binding) 4b. (321 aa)
LOC103480138Lysosomal associated membrane protein 1. (253 aa)
LOC103473662Scavenger receptor class B, member 2c; Belongs to the CD36 family. (481 aa)
LOC103460107RAB11a, member RAS oncogene family. (215 aa)
LOC103480388Zgc:162171. (251 aa)
rab8bMultiple EGF-like-domains 8. (207 aa)
cltcClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1700 aa)
LOC103474865VPS9 domain-containing protein. (700 aa)
LOC103460086Uncharacterized protein. (206 aa)
tlr2TIR domain-containing protein; Belongs to the Toll-like receptor family. (768 aa)
scarb2Scavenger receptor class B, member 2a; Belongs to the CD36 family. (530 aa)
heatr5bHEAT repeat containing 5B. (2065 aa)
pip4p2Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (257 aa)
rapgef2Rap guanine nucleotide exchange factor (GEF) 2. (1615 aa)
LOC103474828Apolipoprotein A-Ib. (263 aa)
LOC103475390RAB38c, member of RAS oncogene family. (260 aa)
LOC103468194RAB11 family interacting protein 4 (class II) a. (603 aa)
flot2Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (434 aa)
ENSPREP00000010233RAB9B, member RAS oncogene family. (220 aa)
nod2Nucleotide-binding oligomerization domain containing 2. (996 aa)
ENSPREP00000009603RAB5A, member RAS oncogene family, a. (57 aa)
LOC103463719RAB11B, member RAS oncogene family, a. (280 aa)
LOC103463721RAB11B, member RAS oncogene family, b. (218 aa)
LOC103468143AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (938 aa)
RABGEF1RAB guanine nucleotide exchange factor 1. (291 aa)
LOC103480941TIR domain-containing protein. (809 aa)
stx6Syntaxin 6; Belongs to the syntaxin family. (255 aa)
sh3d21SH3 domain containing 21. (495 aa)
LOC103460673VPS9 domain-containing protein. (710 aa)
Lpar2Lysophosphatidic acid receptor 2a; Belongs to the G-protein coupled receptor 1 family. (363 aa)
inpp5bInositol polyphosphate-5-phosphatase B. (905 aa)
LOC103460653Si:dkey-16l2.16. (209 aa)
tirapToll-interleukin 1 receptor (TIR) domain containing adaptor protein. (231 aa)
LOC103477863RAB5A, member RAS oncogene family, b. (216 aa)
LOC103474743Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1685 aa)
pik3c3Phosphatidylinositol 3-kinase catalytic subunit type 3. (888 aa)
srgap2SLIT-ROBO Rho GTPase activating protein 2. (1124 aa)
LOC103468815CDC42 effector protein (Rho GTPase binding) 4a. (346 aa)
rapgef6Rap guanine nucleotide exchange factor (GEF) 6. (1611 aa)
LOC103458107EH-domain containing 4; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (546 aa)
ENSPREP00000004746V-SNARE coiled-coil homology domain-containing protein. (94 aa)
ENSPREP00000004733Uncharacterized protein. (288 aa)
rin1Si:ch211-168d1.3. (789 aa)
stam2Signal transducing adaptor molecule (SH3 domain and ITAM motif) 2. (516 aa)
amnAmnion associated transmembrane protein. (498 aa)
LOC103462258AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (956 aa)
RIN2Ras and Rab interactor 2. (993 aa)
rab32RAB32a, member RAS oncogene family. (223 aa)
inpp5fInositol polyphosphate-5-phosphatase F. (1159 aa)
atg14Autophagy related 14. (506 aa)
dctDopachrome tautomerase. (528 aa)
LOC103471313Toll-like receptor 1. (804 aa)
CD2APCD2 associated protein. (670 aa)
RAB9ARAB9A, member RAS oncogene family. (202 aa)
ENSPREP00000002434Uncharacterized protein. (135 aa)
LOC103474679RAB guanine nucleotide exchange factor (GEF) 1, like. (508 aa)
unc93b1Unc-93 homolog B1, TLR signaling regulator. (622 aa)
LOC103481437Solute carrier family 18 member A3. (518 aa)
appl1Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1. (708 aa)
lpar1Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (351 aa)
stx10Syntaxin 10. (284 aa)
ENSPREP00000000256G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (353 aa)
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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